Biomimetic Approaches in Coatings Synthesis

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 8012

Special Issue Editors


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Guest Editor
“Laser-Surface-Plasma Interactions” Laboratory, Lasers Department, National Institute for Lasers, Plasma and Radiation Physics (INFLPR), 409A Atomistilor Street, 077125 Magurele, Romania
Interests: heat transfer at the micro/nano-scale from computation to experiment, including thermophysical properties measurement of nanostructured materials for different applications ranging from thermoelectric to medical
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
National Institute for Lasers, Plasma and Radiation Physics (INFLPR), “Laser-Surface-Plasma Interactions” Laboratory, Lasers Department, 409A Atomistilor street, 077125 Magurele, Ilfov, Romania
Interests: laser processing of materials; synthesis of thin films by different pulsed laser techniques; biomaterials; biomimetic-modified metallic implants; polymeric coatings; drug delivery applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite you to submit to a Special Issue on the “Biomimetic approach in coatings synthesis”. In order to respond to the increasing demands of medical-targeted applications, the development of new products is required and implies the attainment of new functionalized materials and permanent optimization of coating systems. Recently, research on surfaces functionalization through less invasive, biomimetic approaches has been at the forefront of optimizing biointegration, bioactivation, and biomechanics. Both physical and chemical deposition techniques could be employed for coatings and thin films synthesis for targeted medical applications. Furthermore, different wet-chemistry steps and pyrolysis/combustion methods could also be applied in composite coatings synthesis .

Significant efforts are being made to continually develop new and improved biomimetic approaches for coatings synthesis to be used in biomedical applications.

In this context, this Special Issue aims to cover the recent experimental and theoretical developments in the field of biomimetic coatings and films, with focus on their preparation, characterization, applications, and industrialization. Researchers are invited to contribute manuscripts in the form of original full-length articles and critical reviews.

Potential topics include, but are not limited to:

  1. Medical thin film morphology, structure, and other properties induced by the applied deposition method.
  2. Deposition/growth and characterization of nanocomposite or multicomponent thin films for medical coatings.
  3. Nanoengineering on films to form nanotextured/nanofunctionalized surfaces, with the aim of bringing novel properties or functionalities over their bulk counterparts.
  4. Biodegradable coatings and interfaces
  5. Interactions of bio(macro)molecules with surfaces and skin medical remediation
  6. Improved implant surfaces for enhanced bioactivity, and advantageous cell–surface interactions to assist in regenerating tissue.

Dr. Anita Visan
Dr. Gianina Popescu-Pelin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • deposition techniques
  • thin-films
  • medical devices
  • bioactivity
  • biomimicry

Published Papers (5 papers)

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Research

19 pages, 8183 KiB  
Article
Incorporation of Ca, P, Mg, and Zn Elements in Ti-30Nb-5Mo Alloy by Micro-Arc Oxidation for Biomedical Implant Applications: Surface Characterization, Cellular Growth, and Microorganisms’ Activity
by Giovana Collombaro Cardoso, Katia Barbaro, Pedro Akira Bazaglia Kuroda, Luca Imperatori, Angela De Bonis, Roberto Teghil, Mariangela Curcio, Elisa Innocenzi, Victoria Yu. Grigorieva, Gianluca Vadalà, Carlos Roberto Grandini and Julietta V. Rau
Coatings 2023, 13(9), 1577; https://doi.org/10.3390/coatings13091577 - 10 Sep 2023
Cited by 5 | Viewed by 1217
Abstract
Micro-arc oxidation (MAO) is a surface modification technique used to improve the surface properties of titanium alloys, such as corrosion, wear resistance, and osseointegration. In addition to promoting the growth of a porous oxide coating on the sample’s surface, it is also possible [...] Read more.
Micro-arc oxidation (MAO) is a surface modification technique used to improve the surface properties of titanium alloys, such as corrosion, wear resistance, and osseointegration. In addition to promoting the growth of a porous oxide coating on the sample’s surface, it is also possible to incorporate bioactive elements into this coating, such as calcium, phosphorus, and magnesium, as well as elements with antimicrobial action, such as zinc. Thus, this study aimed at the surface modification of the β Ti-30Nb-5Mo alloy by the MAO method, incorporating calcium, phosphorus, magnesium, and zinc to improve osseointegration and promote bactericidal character in the produced coating. The results showed that the porosity, roughness, and crystallinity of the coating tend to increase with increasing Zn concentration in the electrolyte, while the contact angle decreases. The antimicrobial activity was promoted against the E. faecalis and P. aeruginosa bacteria strains and the C. albicans fungus. Incorporating Zn on the surface also did not negatively affect adiposetissue-derived mesenchymal stem cell differentiation, and promoted more significant growth of these cells on the samples’ surface. Full article
(This article belongs to the Special Issue Biomimetic Approaches in Coatings Synthesis)
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15 pages, 5085 KiB  
Article
Microstructure and Properties of Monolayer Ta and Multilayer Ta/Ti/Zr/Ta Coatings Deposited on Biomedical Ti-6Al-4V Alloy by Magnetron Sputtering
by Suli Zhao, Shuguang Liu, Yongjie Xue, Ning Li, Kuixue Xu, Weiwei Qiu, Xuexian Li, Jinbo Wang, Qian Wu and Chunbao Shi
Coatings 2023, 13(7), 1234; https://doi.org/10.3390/coatings13071234 - 11 Jul 2023
Cited by 2 | Viewed by 1128
Abstract
Two types of coatings, i.e., monolayer Ta and multilayer Ta/Ti/Zr/Ta coatings, were deposited on biomedical Ti6Al4V (TC4) alloy by magnetron sputtering to improve its performance. To evaluate the effect of the two coatings on the alloy properties, the microstructure, composition, mechanical and tribological [...] Read more.
Two types of coatings, i.e., monolayer Ta and multilayer Ta/Ti/Zr/Ta coatings, were deposited on biomedical Ti6Al4V (TC4) alloy by magnetron sputtering to improve its performance. To evaluate the effect of the two coatings on the alloy properties, the microstructure, composition, mechanical and tribological properties, in vitro biocompatibility, and corrosion resistance were investigated. The results showed that α-Ta exists in the monolayer Ta coating, while α-Ta and β-Ta phases coexist in the multilayer Ta/Ti/Zr/Ta coating. The multilayer Ta/Ti/Zr/Ta coating possessed the highest hardness and the monolayer Ta coating had the lowest friction coefficient compared to the Ti6Al4V alloy. The friction and wear tests revealed that the anti-wear performance of the Ta coating is the best, followed by that of the Ta/Ti/Zr/Ta coating, while the anti-wear performance of TC4 alloy is relatively poor in comparison with the Ta and Ta/Ti/Zr/Ta coatings. The wear resistance of the multilayer Ta/Ti/Zr/Ta coating under low normal load is better than that under high load normal load. Finally, the in vitro and electrochemical corrosion tests showed that the Ta coating modification provides better biocompatibility and corrosion resistance than those of the uncoated Ti6Al4V alloy. Full article
(This article belongs to the Special Issue Biomimetic Approaches in Coatings Synthesis)
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18 pages, 3309 KiB  
Article
Titanium Implant Alloy Modified by Electrochemically Deposited Functional Bioactive Calcium Phosphate Coatings
by Jozefina Katić, Sara Krivačić, Željka Petrović, Dajana Mikić and Marijan Marciuš
Coatings 2023, 13(3), 640; https://doi.org/10.3390/coatings13030640 - 17 Mar 2023
Cited by 7 | Viewed by 1805
Abstract
Calcium phosphate-based (CaP) bioceramic materials are widely used in the field of bone regeneration, both in orthopaedics and in dentistry, due to their good biocompatibility, osseointegration and osteoconduction. The formation of CaP coatings on high-strength implant materials such as titanium alloys combines the [...] Read more.
Calcium phosphate-based (CaP) bioceramic materials are widely used in the field of bone regeneration, both in orthopaedics and in dentistry, due to their good biocompatibility, osseointegration and osteoconduction. The formation of CaP coatings on high-strength implant materials such as titanium alloys combines the superior mechanical properties of metals with the osteoconductive properties of CaP materials. In this work, the electrochemically assisted deposition of CaP coatings on the titanium alloy, TiAlNb, which is commonly used commercially as an implant material in orthopaedic devices, was examined. The barrier properties (electronic properties) of unmodified and CaP-modified titanium alloy were tested in situ in a simulated physiological solution, Hanks’ solution, under in vitro conditions of real implant applications using electrochemical impedance spectroscopy (EIS). The morphology and microstructure of the obtained CaP deposit were characterised by scanning electron microscopy (SEM) and chemical composition was assessed by energy dispersive X-ray spectroscopy (EDS) and attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). The aim was to investigate the effect of calcium phosphate CaP coating on the corrosion resistance of the titanium TiAlNb alloy and to understand better the deposition process in the production of bioactive functional coatings on metallic implant materials. Full article
(This article belongs to the Special Issue Biomimetic Approaches in Coatings Synthesis)
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13 pages, 2496 KiB  
Article
Development of a Surface Treatment to Achieve Long-Lasting Antimicrobial Properties and Non-Cytotoxicity through Simultaneous Incorporation of Ag and Zn via Two-Step Micro-Arc Oxidation
by Yusuke Tsutsumi, Harumi Tsutsumi, Tomoyo Manaka, Peng Chen, Maki Ashida, Hideki Katayama and Takao Hanawa
Coatings 2023, 13(3), 627; https://doi.org/10.3390/coatings13030627 - 16 Mar 2023
Cited by 1 | Viewed by 1550
Abstract
A customized micro-arc oxidation (MAO) treatment technique was developed to obtain antibacterial properties with no toxicity on Ti surfaces. A two-step MAO treatment was used to fabricate a specimen containing both Ag and Zn in its surface oxide layer, and the optimal incorporation [...] Read more.
A customized micro-arc oxidation (MAO) treatment technique was developed to obtain antibacterial properties with no toxicity on Ti surfaces. A two-step MAO treatment was used to fabricate a specimen containing both Ag and Zn in its surface oxide layer, and the optimal incorporation conditions were determined. Surface characterization by EDS was performed followed by the antibacterial properties against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) and osteogenic cell compatibility evaluations. In addition, metal ion release tests were performed to evaluate the contents of Ag and Zn and the ion release behavior in order to simulate practical usage. MAO-treated specimens prepared using proper concentrations of Ag and Zn (0.5Ag-5Zn: 0.5 mM AgNO3 and 5.0 mM ZnCl, respectively) exhibited excellent antibacterial properties against E. coli and S. aureus and no toxicity to MC3T3-E1 in antibacterial and cytotoxic evaluations, respectively. The antibacterial property of 0.5Ag-5Zn against S. aureus was sustained even after two months of immersion in physiological saline, simulating the in vivo environment. Full article
(This article belongs to the Special Issue Biomimetic Approaches in Coatings Synthesis)
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11 pages, 2835 KiB  
Article
Physico-Mechanical Properties of a Newly Developed Base Material Containing Mineral Trioxide Aggregate
by Keigo Nakamura, Noriko Horasawa, Toshiyuki Okuse, Ryutaro Uchikawa, Katsumitsu Shimada, Akihiro Kuroiwa, Satoshi Murakami, Hiromasa Hasegawa and Atsushi Kameyama
Coatings 2023, 13(3), 597; https://doi.org/10.3390/coatings13030597 - 11 Mar 2023
Viewed by 1608
Abstract
The aim of this study was to evaluate the physico-mechanical properties of a new cavity base material containing mineral trioxide aggregate, LA-T1, prototyped by Neo Dental Chemical Products for indirect restoration. Three base materials, LA-T1, Cavios (CAV, Neo Dental Chemical Products), and Bulk [...] Read more.
The aim of this study was to evaluate the physico-mechanical properties of a new cavity base material containing mineral trioxide aggregate, LA-T1, prototyped by Neo Dental Chemical Products for indirect restoration. Three base materials, LA-T1, Cavios (CAV, Neo Dental Chemical Products), and Bulk Base Hard (BBH, Sun Medical), were examined. The depth of cure, microshear bond strength with a resin-based luting cement, and the compressive strength of these materials were investigated. The depth of cure of LA-T1 was similar to that of CAV, while the depth of cure of BBH was above the measurement limit. The distance from the base material to the light source, 0 mm and 4 mm, did not significantly affect the depth of cure of all materials. The microshear bond strength of LA-T1 bonded to a resin-based luting cement was slightly higher than that of CAV and similar to that of BBH, both of which were bonded to the same luting cement under the same conditions. The compressive strength of LA-T1 was similar to that of CAV but less than that of BBH. The results of this study indicate that LA-T1 has properties that are similar to those of CAV and thus can be clinically applied. Full article
(This article belongs to the Special Issue Biomimetic Approaches in Coatings Synthesis)
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