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Clinics and Practice
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Clinical Treatment of End-Stage Renal Diseases: Hemodialysis, Peritoneal Dialysis, and...
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Clinical Treatment of End-Stage Renal Diseases: Hemodialysis, Peritoneal Dialysis, and Kidney Transplantation

A special issue of Clinics and Practice (ISSN 2039-7283).

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 7075

Special Issue Editors

Dr. Wisit Cheungpasitporn

E-Mail Website
Guest Editor
Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA
Interests: artificial Intelligence; machine learning; meta-analysis; acute kidney injury; clinical nephrology; kidney transplantation
Special Issues, Collections and Topics in MDPI journals
Dr. Wisit Kaewput

E-Mail Website
Guest Editor
Department of Medicine, Phramongkutklao College of Medicine, Bangkok, Thailand
Interests: machine learning; kidney transplantation; observational studies; statistical analysis; epidemiology
Special Issues, Collections and Topics in MDPI journals
Dr. Charat Thongprayoon

E-Mail Website
Guest Editor
Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA
Interests: artificial intelligence; machine Learning; nephrology; acute kidney injury; clinical nephrology; kidney transplantation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

More than a million deaths per year are caused by kidney disease, and the mortality rate associated with kidney disease is still increasing. Additionally, the rapid increase in the number of patients with end-stage kidney disease (ESKD) requiring dialysis treatment or kidney transplantation is a global problem imposing a high burden on the world health economy. It is, therefore, crucial that ESKD is identified, monitored, and treated and that preventative and therapeutic measures addressing ESKD are systematically implemented worldwide. Nowadays, some kidney-related problems have been thoroughly studied and investigated. However, much is still unknown and/or unclear regarding kidney disease, in terms of pathogenesis, outcomes, and novel treatment strategies.

In this Special Issue, we are honored to invite all researchers and clinicians interested in kidney diseases, dialysis treatment, and kidney transplantation, with regard to these above aspects, to submit contributions that aim to advance knowledge in these essential fields. Original investigations, review articles, and short communications are especially welcome.

Potential topics include, but are not limited to, the following:

  • Aging of the peritoneal dialysis membrane;
  • Pathophysiology and classification of kidney disease;
  • Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients;
  • Association between fear of falling and a history of falls in patients with end-stage renal disease on hemodialysis;
  • Epithelial–mesenchymal transition correlated with renal function;
  • The reversibility of renal fibrosis;
  • Chronic kidney disease and clinical outcomes;
  • Current recommendations regarding the evaluation of cognitive function in organ transplant candidates;
  • Consensus definitions of clinical trial outcomes for kidney failure;
  • Determinants of outcomes of acute kidney injury: clinical predictors;
  • The effect of guided meditation on quality of life in patients with end-stage renal disease (ESRD) receiving maintenance hemodialysis;
  • Current treatment approaches for amyloidosis-associated kidney disease;
  • Treatment of steroid-sensitive nephrotic syndrome: new guidelines.

Best regards,

Dr. Wisit Cheungpasitporn
Dr. Wisit Kaewput
Dr. Charat Thongprayoon
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Clinics and Practice is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • end-stage kidney disease
  • kidney disease
  • dialysis
  • hemodialysis
  • peritoneal dialysis
  • kidney transplantation
  • renal transplantation
  • transplantation

Published Papers (3 papers)

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Research

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12 pages, 256 KiB  
Article
Quality of Life among Peritoneal and Hemodialysis Patients: A Cross-Sectional Study
by Fadel AlRowaie, Abdullah Alaryni, Abdullah AlGhamdi, Renad Alajlan, Razan Alabdullah, Raed Alnutaifi, Raneem Alnutaifi, Amani Aldakheelallah, Alanoud Alshabanat, Abdullah Bin Shulhub, Othillah Moazin, Rayan Qutob, Enad Alsolami and Osamah Hakami
Clin. Pract. 2023, 13(5), 1215-1226; https://doi.org/10.3390/clinpract13050109 - 30 Sep 2023
Cited by 3 | Viewed by 1309
Abstract
Background: The quality of life (QoL) of patients with end-stage kidney disease (ESKD) who undergo dialysis is a reliable predictor of their long-term survival. Hemodialysis is the most common form of kidney replacement therapy for ESKD, followed by peritoneal dialysis. This study aimed [...] Read more.
Background: The quality of life (QoL) of patients with end-stage kidney disease (ESKD) who undergo dialysis is a reliable predictor of their long-term survival. Hemodialysis is the most common form of kidney replacement therapy for ESKD, followed by peritoneal dialysis. This study aimed to identify the factors affecting QoL in ESKD patients treated with peritoneal dialysis (PD) or hemodialysis (HD) in Riyadh, Saudi Arabia. Methods: A cross-sectional study was conducted between June and July 2021 to assess the QoL of patients with ESKD who underwent peritoneal dialysis and hemodialysis. Patients who had been on dialysis for at least one year were included. The Arabic version of the Quality of Life Index–Dialysis (QLI-D) version III was used to measure the QoL. Results: A total of 210 patients completed the questionnaire. The overall QLI score was 21.73 ± 4.2, with subscales for health and functioning (20.35 ± 5.2), social and economic (20.20 ± 4.8), psychological/spiritual (23.94 ± 4.9), and family (24.95 ± 4.5). The QLI scores for PD and HD patients were 21.80 ± 4.4 and 21.72 ± 4.1, respectively. SOCSUB (p = 0.031) was significantly associated with group and income, whereas QLI (p = 0.003), HFSUB (p = 0.013), SOCSUB (p = 0.002), and PSPSUB (p = 0.003) were significantly correlated with group and years of dialysis. Conclusion: The study found that patients were most satisfied with their family, health and functioning, and social/economic subscales. Income and years of dialysis were found to be predictive factors of QoL. Overall, peritoneal patients in this study demonstrated a better QoL than HD patients. Full article
(This article belongs to the Special Issue Clinical Treatment of End-Stage Renal Diseases: Hemodialysis, Peritoneal Dialysis, and Kidney Transplantation)
11 pages, 2833 KiB  
Article
Effects of Mediterranean Diet, DASH Diet, and Plant-Based Diet on Outcomes among End Stage Kidney Disease Patients: A Systematic Review and Meta-Analysis
by Mariam Charkviani, Charat Thongprayoon, Supawit Tangpanithandee, Pajaree Krisanapan, Jing Miao, Michael A. Mao and Wisit Cheungpasitporn
Clin. Pract. 2023, 13(1), 41-51; https://doi.org/10.3390/clinpract13010004 - 28 Dec 2022
Cited by 1 | Viewed by 3180
Abstract
Background: The Mediterranean, Dietary Approach to Stop Hypertension (DASH), and plant-based diets may provide cardiovascular benefit to the general population. However, data on their effect on end stage kidney disease (ESKD) patients are limited. This systematic review aims to assess the impact of [...] Read more.
Background: The Mediterranean, Dietary Approach to Stop Hypertension (DASH), and plant-based diets may provide cardiovascular benefit to the general population. However, data on their effect on end stage kidney disease (ESKD) patients are limited. This systematic review aims to assess the impact of Mediterranean, DASH, and plant-based diets on outcomes among ESKD patients. Methods: A literature review was conducted in EMBASE, MEDLINE, and Cochrane databases from inception through September 2022 to identify studies that assess the clinical outcomes of Mediterranean, DASH, or plant-based diets on ESKD patients on hemodialysis (HD) or peritoneal dialysis (PD). Effect estimates from the individual studies were derived utilizing the random-effect, generic inverse variance approach of DerSimonian and Laird. Results: Seven studies with 9400 ESKD patients (8395 HD and 1005 PD) met the eligibility criteria and were included in the data analysis. Pooled odds ratios (ORs) of mortality for ESKD patients who adhered to the Mediterranean versus plant-based diet were 0.49 (95% CI: 0.07–3.54; two studies, I2 = 67%) and 0.87 (95% CI: 0.75–1.01; two studies, I2 = 0%), respectively. Data on mortality for ESKD patients on a DASH diet were limited to one study with an OR of 1.00 (95% CI: 0.89–1.12). The pooled OR of cardiovascular mortality among ESKD patients who adhered to a plant-based diet was 0.86 (95% CI: 0.68–1.08; two studies, I2 = 0%), compared to those who did not. Data on cardiovascular mortality among those with Mediterranean and DASH diet were limited to one study with ORs of 1.14 (95% CI: 0.90–1.43) and 1.19 (95% CI: 0.99–1.43), respectively. Mediterranean diet adherence was found to be associated with reduced risk of left ventricular hypertrophy (LVH) with an OR of 0.82 (95% CI: 0.68–0.99) in a study including 127 ESKD patients. The risk of hyperkalemia was not significant among those with a plant-based diet with an OR of 1.00 (95% CI: 0.94–1.07) in a study including 150 ESKD patients. Conclusions: While our systematic review demonstrated no significant associations of Mediterranean, DASH, and plant-based diets with reduced all-cause mortality or cardiovascular mortality, there was also no evidence that suggested harmful effects of these diets to ESKD patients. Full article
(This article belongs to the Special Issue Clinical Treatment of End-Stage Renal Diseases: Hemodialysis, Peritoneal Dialysis, and Kidney Transplantation)
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15 pages, 2800 KiB  
Review
Past, Current, and Future Perspectives on Transplanting Acute Kidney Injury Kidneys
by Rachana Punukollu, Margaret Ryan, Suman Misra, Pooja Budhiraja, Stephanie Ohara, Kayla Kumm, Giselle Guerra, Kunam S. Reddy, Raymond Heilman and Caroline C. Jadlowiec
Clin. Pract. 2023, 13(4), 944-958; https://doi.org/10.3390/clinpract13040086 - 14 Aug 2023
Cited by 1 | Viewed by 1596
Abstract
(1) Background: Acute kidney injury (AKI) kidneys have high non-utilization rates due to concerns regarding unfavorable outcomes. In this paper, we aimed to review the past, present, and future opinions on AKI kidneys. (2) Methods: A PubMed search was conducted for topics relevant [...] Read more.
(1) Background: Acute kidney injury (AKI) kidneys have high non-utilization rates due to concerns regarding unfavorable outcomes. In this paper, we aimed to review the past, present, and future opinions on AKI kidneys. (2) Methods: A PubMed search was conducted for topics relevant to AKI kidney transplantation. (3) Results: Current short- and long-term data on AKI kidneys have demonstrated good outcomes including favorable graft function and survival. The role of procurement biopsies is controversial, but they have been shown to be beneficial in AKI kidneys by allowing clinicians to differentiate between reversible tubular injury and irreversible cortical necrosis. Machine perfusion has also been applied to AKI kidneys and has been shown to reduce delayed graft function (DGF). The incidence of DGF increases with AKI severity and its management can be challenging. Strategies employed to counteract this have included early initiation of dialysis after kidney transplantation, early targeting of adequate immunosuppression levels to minimize rejection risk, and establishment of outpatient dialysis. (4) Conclusions: Despite good outcomes, there continue to be barriers that impact AKI kidney utilization. Successful strategies have included use of procurement biopsies or machine perfusion and expectant management of DGF. With increasing experience, better use of AKI kidneys can result in additional opportunities to expand the donor pool. Full article
(This article belongs to the Special Issue Clinical Treatment of End-Stage Renal Diseases: Hemodialysis, Peritoneal Dialysis, and Kidney Transplantation)
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