Special Issue "Challenges and Advances in Pediatric and Neonatal Critical Care"

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neonatology".

Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 1144

Special Issue Editor

Unit of Pediatrics and Pediatric Emergency, AOU "Rodolico-San Marco", PO "San Marco", University of Catania, 95124 Catania, Italy
Interests: neurological disease; neurocutaneous diseases and neuromuscular disease in children and in newborns; epilepsy and encephalopathies; pediatric ultrasound; children pharmacology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue focuses on "Pediatric and Neonatal Intensive Care". Significant progress has been made in the field of pediatric and neonatal intensive care over the past decade. Pediatric critical care medicine emerged in the 1970s and has expanded dramatically since then. The field has made major advances in the areas of lung injury, sepsis, head injury, and postoperative care. The role of the pediatric intensivist is to provide supportive care during cardiorespiratory and/or multiorgan failure or recovery from surgery or trauma. In addition, care often continues even after discharge since we are often dealing with children with a high demand for care complexity. Intensivists coordinate complex treatment plans with multiple participants to assist in the care of critically ill children. The first approach to the critical child often takes place in the pediatric emergency room. Thus, the pediatrician must be able to filter out those children who need intensive care and provide basic necessities.

Submissions of original articles, systematic reviews, short communications, and other types of articles on related topics are welcome. All manuscripts will follow standard journal peer review practices, and those accepted for publication will appear in the Special Issue on "Challenges and Advances in Pediatric and Neonatal Critical Care". We look forward to receiving your contributions to the Special Issue.

Dr. Silvia Marino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • emergency
  • critical care
  • multidisciplinary care
  • intensive care
  • sub-intensive care
  • children
  • newborn
  • acute respiratory failure
  • highly complex care
  • status epilepticus
  • ventilation

Published Papers (1 paper)

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Research

9 pages, 415 KiB  
Article
Indirect Neonatal Hyperbilirubinemia and the Role of Fenofibrate as an Adjuvant to Phototherapy
Children 2023, 10(7), 1192; https://doi.org/10.3390/children10071192 - 10 Jul 2023
Cited by 1 | Viewed by 863
Abstract
Background: One of the most prevalent illnesses in neonates that needs care and treatment is neonatal jaundice. Several drugs are used as pharmacological modalities for treating hyperbilirubinemia, like intravenous immunoglobulin, D-penicillamine, metalloporphyrin, phenobarbital, zinc sulfate and clofibrate. Previous studies suggest the usefulness of [...] Read more.
Background: One of the most prevalent illnesses in neonates that needs care and treatment is neonatal jaundice. Several drugs are used as pharmacological modalities for treating hyperbilirubinemia, like intravenous immunoglobulin, D-penicillamine, metalloporphyrin, phenobarbital, zinc sulfate and clofibrate. Previous studies suggest the usefulness of fenofibrate in the treatment of hyperbilirubinemia. Objectives: The study aims at assessing the effectiveness of oral fenofibrate in the treatment of indirect neonatal hyperbilirubinemia in full-term neonates. Method: This is a quasi-experimental study that was conducted at Heevi Pediatrics Teaching Hospital in Duhok, which is located in the Kurdistan Region of Iraq. It involved term infants who had jaundice. The neonates who were eligible for the study were randomly assigned to one of two groups: the intervention group or the control group. Both groups were treated with conventional phototherapy. Fenofibrate was administered in a single oral dose of 10 mg/kg to the participants in the intervention group. Throughout the entirety of the treatment, levels of total serum bilirubin were compared and contrasted between the two groups. Results: After 12 h of treatment, a statistically significant difference (p-value = 0.001) was seen in the serum bilirubin levels between the two groups. The difference in serum bilirubin levels became significantly progressively pronounced after 24, 48, and 72 h. The average time of discharge was 63.6 h for the intervention group and 90.9 h for the control group, and this difference was statistically significant (p-value < 0.001). Conclusions: The time it takes to lower high bilirubin levels in neonates may be shortened by combining conventional phototherapy with a single oral dosage of 10 mg/kg fenofibrate. Consequently, these neonates will experience a shorter hospitalization and an accelerated discharge from the hospital. Full article
(This article belongs to the Special Issue Challenges and Advances in Pediatric and Neonatal Critical Care)
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