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Children
Special Issues
Gynaecological Care in Childhood and Adolescence
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Special Issue "Gynaecological Care in Childhood and Adolescence"

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Global and Public Health".

Deadline for manuscript submissions: closed (25 October 2023) | Viewed by 2743

Special Issue Editors

Dr. Lina Michala

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Athens, Greece
Interests: pediatric and adolescent gynecology; adolescent medicine; young adults; ovary; women's health; obstetrics; reproduction biology; reproductive medicine; child development
Dr. Anastasia Vatopoulou
E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, University of Ioannina, Ioannina, Greece
Interests: pediatric and adolescent gynecology; adolescent medicine; young adults; ovary; women's health; obstetrics; reproduction biology; reproductive medicine; child development

Special Issue Information

Dear Colleagues,

Pediatric and adolescent gynecology is a fast-advancing field with links to a multitude of other disciplines. The scope of topics covered in this Special Issue includes, but is not limited to, ovarian pathology, congenital anomalies, differences in sex development, amenorrhea, sexual health, and child and adolescent sexual abuse. We seek original research articles, case reports, and narrative and systematic reviews that focus on evidence-based practice and practical guidance aimed at improving the reproductive health outcomes of adolescent patients.

Overall, we hope that authors will contribute to the development and advancement of the field with their research. We are committed to providing a platform that presents healthcare providers with information on evidence-based practice and practical guidance in order to further aid in improving the care of adolescent patients. We encourage authors with diverse perspectives and from a range of disciplines, including medicine, public health, and psychology, to submit their manuscripts for consideration.

Dr. Lina Michala
Dr. Anastasia Vatopoulou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric gynecology
  • reproductive health
  • adolescent health
  • adolescent sexual health
  • child sexual abuse
  • differences of sexual development
  • intersex
  • teenage pregnancy
  • congenital uterine anomalies

Published Papers (2 papers)

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Review

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24 pages, 13183 KiB  
Review
Ovarian Masses in Children and Adolescents: A Review of the Literature with Emphasis on the Diagnostic Approach
by
Effrosyni Birbas
,
Theofilos Kanavos
,
Fani Gkrozou
,
Chara Skentou
,
Angelos Daniilidis
and
Anastasia Vatopoulou
Children 2023, 10(7), 1114; https://doi.org/10.3390/children10071114 - 27 Jun 2023
Viewed by 1845
Abstract
Most abdominal masses in the pediatric population derive from the ovaries. Ovarian masses can occur in all ages, although their incidence, clinical presentation and histological distribution vary among different age groups. Children and adolescents may develop non-neoplastic ovarian lesions, such as functional cysts, [...] Read more.
Most abdominal masses in the pediatric population derive from the ovaries. Ovarian masses can occur in all ages, although their incidence, clinical presentation and histological distribution vary among different age groups. Children and adolescents may develop non-neoplastic ovarian lesions, such as functional cysts, endometrioma, torsion, abscess and lymphangioma as well as neoplasms, which are divided into germ cell, epithelial, sex-cord stromal and miscellaneous tumors. Germ cell tumors account for the majority of ovarian neoplasms in the pediatric population, while adults most frequently present with epithelial tumors. Mature teratoma is the most common ovarian neoplasm in children and adolescents, whereas dysgerminoma constitutes the most frequent ovarian malignancy. Clinical manifestations generally include abdominal pain, palpable mass, nausea/vomiting and endocrine alterations, such as menstrual abnormalities, precocious puberty and virilization. During the investigation of pediatric ovarian masses, the most important objective is to evaluate the likelihood of malignancy since the management of benign and malignant lesions is fundamentally different. The presence of solid components, large size and heterogenous appearance on transabdominal ultrasonography, magnetic resonance imaging and computed tomography indicate an increased risk of malignancy. Useful tumor markers that raise concern for ovarian cancer in children and adolescents include alpha-fetoprotein, lactate dehydrogenase, beta subunit of human chorionic gonadotropin, cancer antigen 125 and inhibin. However, their serum levels can neither confirm nor exclude malignancy. Management of pediatric ovarian masses needs to be curative and, when feasible, function-preserving and minimally invasive. Children and adolescents with an ovarian mass should be treated in specialized centers to avoid unnecessary oophorectomies and ensure the best possible outcome. Full article
(This article belongs to the Special Issue Gynaecological Care in Childhood and Adolescence)
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Other

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9 pages, 622 KiB  
Systematic Review
Genital GVHD in Female Children and Adolescents: A Systematic Review of Case Reports and Case Series
by
Maria Tsimeki
,
Antonios Tsimpidakis
,
Stella Roidi
,
Themos Gregoriadis
,
Alexandra Soldatou
,
Vasiliki Kitra
and
Lina Michala
Children 2023, 10(9), 1463; https://doi.org/10.3390/children10091463 - 28 Aug 2023
Viewed by 622
Abstract
Genital graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT) is an underdiagnosed manifestation of chronic GVHD. Few articles have been published in pediatric populations, and there are no established guidelines for the management of this condition in children. This study aims to [...] Read more.
Genital graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT) is an underdiagnosed manifestation of chronic GVHD. Few articles have been published in pediatric populations, and there are no established guidelines for the management of this condition in children. This study aims to provide a systematic literature review of the published studies and cases of genital (vulvovaginal) GVHD in girls and adolescents post HSCT, with a focus on the time of diagnosis and clinical manifestations. The authors searched for English-language articles published after 1990, which included full patient details. Thirty-two cases of female patients under 20 years of age were identified. The median time of diagnosis was 381 days (IQR: 226–730 days), and 83% of patients developed Grade 3 vulvovaginal GVHD. Based on these observations, an early pediatric gynecologic examination of these patients, soon within the first year after HSCT, could be suggested for early diagnosis, treatment initiation and prevention of long-term complications. Full article
(This article belongs to the Special Issue Gynaecological Care in Childhood and Adolescence)
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