Special Issue "Pathophysiology of Schizophrenia in Adolescents"
Deadline for manuscript submissions: 31 January 2024 | Viewed by 97
Schizophrenia is a neurodevelopmental disorder in which behavioral and neurobiological abnormalities gradually emerge in the developing brain, eventually resulting in the full onset of schizophrenia often around late adolescence/early adulthood. The adolescent period is of importance, as several pathophysiological alterations occur specifically during this time point. Alterations range from major modifications in several neurotransmitter systems to changes in grey matter volumes and activity patterns of distinct neuronal circuits. These combined pathophysiological findings are suggested to mark the end point of a long-standing abnormal trajectory and may constitute the turning point in transitioning into the full spectrum of the disorder. Further expanding our knowledge of the pathophysiological processes in the adolescent brain is needed for the future prevention and sufficient treatment of this devastating disorder.
This Special Issue will discuss the vast pathophysiological changes related to schizophrenia found in the adolescent brain. The topics can be varied and cover any relevant content, ranging from molecular to neuronal circuit changes; however, as a given pathophysiological finding rarely tends to stand alone, special emphasis will be given to elements in which the complex interplay between different pathophysiological processes is discussed.
Dr. Henriette Edemann Callesen
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- neuronal circuits