Clinical and Basic Research on Chronic Rhinosinusitis in Children

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Allergy and Immunology".

Deadline for manuscript submissions: closed (15 November 2023) | Viewed by 1292

Special Issue Editors


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Guest Editor
Otorhinolaryngology Unit, Department of Pediatric Surgery, Vittore Buzzi Children's Hospital, Milan, Italy
Interests: rhinosinusitis; pediatric; quality of life; nasal microbiome; allergy; biologics; endoscopic sinus surgery; inflammation; asthma

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Guest Editor
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, MI, Italy
Interests: severe asthma; nasal polyps; airway inflammation; biomarkers; anaphylaxis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Rhinosinusitis is a common diagnosis that all of us have encountered. Chronic sinusitis is a significant problem for the pediatric population, despite being less common than acute sinusitis and receiving less attention than its adult counterpart. In recent years, there has been a growing interest in this clinical condition, and the goal of this Special Issue is to gather various clinical and research experiences on this subject. Therefore, submissions of articles focusing on the pathophysiology of chronic sinusitis and the role of the microbiome will be welcomed. Clinical works from pediatrics, otolaryngology, immunology of pneumology, etc. will also be appreciated, with a focus on both medical and surgical treatments, combined and multidisciplinary approaches, as well as the new frontier of biological therapy.

Dr. Antonio Mario Bulfamante
Dr. Enrico Heffler
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • rhinosinusitis
  • pediatric
  • quality of life
  • nasal microbiome
  • allergy
  • biologics
  • endoscopic sinus surgery
  • inflammation
  • asthma

Published Papers (1 paper)

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Research

11 pages, 566 KiB  
Article
Allergic Rhinitis as an Independent Risk Factor for Postoperative Recurrence of Children Chronic Sinusitis
by Caixia Zhang, Hua Zhang, Qingping Tang, Junyi Zhang, Shuo Wang, Zhihai Xie and Weihong Jiang
Children 2023, 10(7), 1207; https://doi.org/10.3390/children10071207 - 12 Jul 2023
Viewed by 939
Abstract
(1) Background: The recurrence rate of childhood recurrent sinusitis varies widely between 12% and 50%, with the postoperative recurrence risk factors remaining largely unidentified. We sought to enhance the understanding of chronic rhinosinusitis (CRS) via a retrospective observational childhood cohort. (2) Methods: The [...] Read more.
(1) Background: The recurrence rate of childhood recurrent sinusitis varies widely between 12% and 50%, with the postoperative recurrence risk factors remaining largely unidentified. We sought to enhance the understanding of chronic rhinosinusitis (CRS) via a retrospective observational childhood cohort. (2) Methods: The study recruited 125 cases. Demographic data and univariate and multivariate logistic regression analyses were conducted to investigate potential risk factors of childhood recurrent sinusitis following functional endoscopic sinus surgery (FESS). (3) Results: A postoperative recurrence rate of 21.6% was determined. Among the participants, 21 cases presented a history of allergic rhinitis (AR), with the remaining 104 cases being AR-free. A significantly heightened recurrence rate was noted in those bearing a history of AR compared to their counterparts devoid of such history (p < 0.000). The fully adjusted logistic regression model indicated a 21.04-fold increased risk of postoperative recurrence in childhood CRS bearing a history of AR compared to those without an AR history (p = 0.000), highlighting the history of AR as an independent risk factor for postoperative childhood recurrent sinusitis (p = 0.001); (4) Conclusions: The data implicate AR as an independent risk factor for postoperative childhood recurrent sinusitis. Full article
(This article belongs to the Special Issue Clinical and Basic Research on Chronic Rhinosinusitis in Children)
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