Special Issue "Neonatal Life Support: Where Do We Go from Here?"

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neonatology".

Deadline for manuscript submissions: 10 June 2024 | Viewed by 1156

Special Issue Editor

Dr. Praveen Chandrasekharan
E-Mail Website
Guest Editor
Division of Neonatology, Department of Pediatrics, University at Buffalo, Buffalo, NY 14260, USA
Interests: neonatal–perinatal medicine

Special Issue Information

Dear Colleagues,

Over the years, we have relied on our training, experience, and guidelines to improve our approach to newborn resuscitation. As our understanding of neonatal physiology (especially from translational research) and clinical research continues to evolve, so does the evidence that supports best practices for neonatal resuscitation. In this Special Issue, we will explore the evolving evidence for neonatal resuscitation and its implications for clinical practice. We will examine the latest research on topics that will help to manage and improve newborn resuscitation and outcomes. For the smallest and most vulnerable patients in our care, this Special Issue will focus on the latest evidence-based practices for neonatal resuscitation.

We invite you to contribute articles on neonatal resuscitation to this Special Issue. Both reviews and original research supporting all aspects of newborn resuscitation will be considered for publication.

Thank you.

Dr. Praveen Chandrasekharan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • periviable infants
  • umbilical cord management
  • respiratory support
  • chest compressions and circulation
  • temperature management
  • medications
  • fluid bolus
  • emergent transfusions
  • debriefing
  • quality improvement

Published Papers (1 paper)

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Research

13 pages, 5185 KiB  
Article
Femoral Occlusion during Neonatal Cardiopulmonary Resuscitation Improves Outcomes in an Ovine Model of Perinatal Cardiac Arrest
Children 2023, 10(11), 1804; https://doi.org/10.3390/children10111804 - 13 Nov 2023
Viewed by 1018
Abstract
Background: The goal of chest compressions during neonatal resuscitation is to increase cerebral and coronary blood flow leading to the return of spontaneous circulation (ROSC). During chest compressions, bilateral femoral occlusion may increase afterload and promote carotid and coronary flow, an effect similar [...] Read more.
Background: The goal of chest compressions during neonatal resuscitation is to increase cerebral and coronary blood flow leading to the return of spontaneous circulation (ROSC). During chest compressions, bilateral femoral occlusion may increase afterload and promote carotid and coronary flow, an effect similar to epinephrine. Our objectives were to determine the impact of bilateral femoral occlusion during chest compressions on the incidence and timing of ROSC and hemodynamics. Methodology: In this randomized study, 19 term fetal lambs in cardiac arrest were resuscitated based on the Neonatal Resuscitation Program guidelines and randomized into two groups: femoral occlusion or controls. Bilateral femoral arteries were occluded by applying pressure using two fingers during chest compressions. Results: Seventy percent (7/10) of the lambs in the femoral occlusion group achieved ROSC in 5 ± 2 min and three lambs (30%) did not receive epinephrine. ROSC was achieved in 44% (4/9) of the controls in 13 ± 6 min and all lambs received epinephrine. The femoral occlusion group had higher diastolic blood pressures, carotid and coronary blood flow. Conclusion: Femoral occlusion resulted in faster and higher incidence of ROSC, most likely due to attaining increased diastolic pressures, coronary and carotid flow. This is a low-tech intervention that can be easily adapted in resource limited settings, with the potential to improve survival and neurodevelopmental outcomes. Full article
(This article belongs to the Special Issue Neonatal Life Support: Where Do We Go from Here?)
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