Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
3.9
4.2
Journals
Chemosensors
Special Issues
Novel Biosensors for Medical Diagnostics
share announcement

Novel Biosensors for Medical Diagnostics

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "(Bio)chemical Sensing".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 2698

Special Issue Editors

Prof. Dr. Laís Canniatti Brazaca

E-Mail Website
Guest Editor
Instituto de Química de São Carlos, Universidade Federal de São Carlos, Sao Carlos, Brazil
Interests: biosensor; adiponectin; synthetic biology; biosensor and diabetes
Prof. Dr. Juliana Cancino

E-Mail Website
Guest Editor
Instituto de Física de São Carlos, Universidade de São Paulo (USP), São Carlos, Brazil
Interests: nanomedicine
Dr. Paulo Augusto Raymundo-Pereira

E-Mail Website
Guest Editor
São Carlos Institute of Physics, University of São Paulo, Sao Paulo 13566-690, Brazil
Interests: sensors and biosensors; nanotechnology; wearable devices; microneedle; biomarkers; diagnostics; clinical, environmental, food and water analysis; internet of things; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biosensors present promising features for improving clinical diagnostics. Besides being able to promote simpler, more rapid, and lower-cost assessments of biomarkers concentrations, the devices are commonly portable and can function with low sample volumes, allowing point-of-care measurements to be performed even in remote settings. Current advances such as the use of new and improved bioreceptors, materials, or innovative detection techniques can enhance the analytical performance of the devices, making them more sensitive and robust. Other recent trends include the use of wearable devices for the continuous monitoring of healthcare status, and the use of artificial intelligence to precisely monitor and analyze the generated data.

This special issue is dedicated to advances in biosensing for medical purposes, accepting papers related to the development and application of new devices for the detection of biomarkers and critical or comprehensive reviews on the theme.

Prof. Dr. Laís Canniatti Brazaca
Prof. Dr. Juliana Cancino
Dr. Paulo Augusto Raymundo-Pereira
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensors
  • clinical diagnostics
  • biomarkers
  • point-of-care
  • microfluidics
  • wearables
  • artificial intelligence

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

14 pages, 2835 KiB  
Article
Highly Crystalline Oxidase-like MnOOH Nanowire-Incorporated Paper Dipstick for One-Step Colorimetric Detection of Dopamine
by Phan Ba Khanh Chau, Thinh Viet Dang and Moon Il Kim
Chemosensors 2023, 11(7), 382; https://doi.org/10.3390/chemosensors11070382 - 07 Jul 2023
Cited by 1 | Viewed by 1006
Abstract
Developing a convenient detection method for dopamine holds a significant incentive due to its high clinical significance. Herein, we synthesize crystalline MnOOH nanowires (MNWs) via a simple solvothermal treatment of KMnO4 and demonstrate that they possess excellent oxidase-like activity owing to the [...] Read more.
Developing a convenient detection method for dopamine holds a significant incentive due to its high clinical significance. Herein, we synthesize crystalline MnOOH nanowires (MNWs) via a simple solvothermal treatment of KMnO4 and demonstrate that they possess excellent oxidase-like activity owing to the presence of pure Mn3+ sites on the MNWs. Particularly, MNWs catalyze the rapid oxidation of dopamine into aminochromes, which show a vivid brown color. The dopamine oxidase-like activity of MNWs follows the typical Michaelis–Mentenkinetics with excellent storage stability. Based on the affirmative catalytic features, a paper dipstick incorporating MNWs in the detection zone is constructed for the one-step colorimetric detection of target dopamine. By immersing the dipstick into the sample solution for 30 min, the sample spontaneously moves to the detection zone due to capillary force, yielding a brown color proportional to the amount of dopamine, which is quantified from an image acquired using a smartphone. With the MNW-containing solution-based assay and MNW-incorporated paper dipstick, dopamine is successfully determined with high selectivity, sensitivity, and detection precision when using spiked human serum and pharmaceutical dopamine injection samples, respectively. Successful analytical values such as the dynamic linear ranges of 3–60 μM and 0.05–7 mM are achieved with the solution-based assay and paper dipstick, respectively, along with excellent detection accuracy (95–99%) and precision (1.0–3.1%). Hence, we developed a simple and efficient nanozyme-based paper dipstick biosensor for dopamine that can be used in point-of-care testing environments. Full article
(This article belongs to the Special Issue Novel Biosensors for Medical Diagnostics)
►▼ Show Figures

Figure 1

14 pages, 3065 KiB  
Article
Additive Manufacturing Sensor for Stress Biomarker Detection
by Vinicius A. O. P. da Silva, Jéssica S. Stefano, Cristiane Kalinke, Juliano A. Bonacin and Bruno C. Janegitz
Chemosensors 2023, 11(5), 306; https://doi.org/10.3390/chemosensors11050306 - 20 May 2023
Cited by 2 | Viewed by 1233
Abstract
This work presents a new additive manufacturing electrochemical device with conductive graphene and polylactic acid (PLA) filament and its application for epinephrine sensing. A three-electrode configuration based on a screen-printed electrode architecture and an easy-to-connect connector was designed. The sensor surface was chemically [...] Read more.
This work presents a new additive manufacturing electrochemical device with conductive graphene and polylactic acid (PLA) filament and its application for epinephrine sensing. A three-electrode configuration based on a screen-printed electrode architecture and an easy-to-connect connector was designed. The sensor surface was chemically treated with dimethylformamide (DMF) to remove the insulating thermoplastic and expose the graphene binding groups. The scanning electron microscopy (SEM) results showed that the surface PLA was removed and the graphene nanofibers exposed, which corroborated the X-ray diffraction spectra (XRD). As a proof of concept, the G-PLA electrode was applied for the determination of epinephrine in human blood samples by square wave voltammetry with a linear range from 4.0 to 100 µmol L−1 and a limit of detection of 0.2 µmol L−1. Based on the results obtained and sensor application, 3D-printed G-PLA proved an excellent choice for epinephrine sensing purposes. Full article
(This article belongs to the Special Issue Novel Biosensors for Medical Diagnostics)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop