Allergy, Asthma and Clinical Immunology

A topical collection in Cells (ISSN 2073-4409). This collection belongs to the section "Cellular Immunology".

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Institute of Clinical Immunotherapy and Advanced Biological Treatments, Pescara, Italy
Interests: cellular and clinical immunology; allergy
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Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, 98125 Messina, Italy
Interests: mediators of inflammation, cytokines, and biomarkers of oxidative stress; immunosenescence; immunogenetics; epigenetics; application of machine learning and deep learning in various fields of medicine
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Allergy and Clinical Immunology, Medicine and Surgery Department, University of Parma, Parma, Italy
Interests: eosinophil gastrointestinal diseases (EoE); food allergy; immunotherapy; asthma; allergic respiratory diseases

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1. Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Italy
2. Personalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy
Interests: chronic rhinosinusitis; nasal polyps; monoclonal antibodies; type 2 inflammation; asthma; allergen immunotherapy; rhinitis
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Unit of Internal Medicine “Guido Baccelli”, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, 70124 Bari, Italy
Interests: multiple myeloma; microenvironment; oncology; angiogenesis; hematology
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Topical Collection Information

Dear Colleagues,

Immunology has seen tremendous scientific advancements in recent decades. The definition of the cellular and molecular mechanisms of innate and adaptive immunity has led to better comprehension of health status and illness. There is a synergy between the adaptive immune system and its innate counterpart, and their defects can provoke inappropriate inflammation, autoimmunity, immunodeficiency, and hypersensitivity reactions. The identification of the cellular and molecular mechanisms at the base of their immune mechanism allowed a precise endotyping of many diseases, with the development of specific immunotherapy.

This Topical Collection is a cooperation between the Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC) and Cells, dedicated to research that can enhance our understanding of the molecular and cellular aspects of allergic and immune diseases. It encompasses all of the cellular and molecular aspects of the genetics, pathogenesis, clinical, pathology, diagnosis, and treatment of allergic as well as immunologic disease.

It is especially dedicated to the following areas and other related topics: T cell and B cell functions, regulatory T cells, natural killer cells, antigen-presenting cells, mast cells and eosinophils, and complement abnormalities. Particular emphasis will be devoted to asthma, rhinoconjunctivitis and rhinosinusitis, atopic dermatitis, urticaria and angioedema, venom hypersensitivity, anaphylaxis and food allergy, immune deficiency, autoimmunity, and immunosenescence. Contributions on the mechanisms of the basis of the effectiveness of immunotherapy, immune modulators, and biologics will be particularly appreciated.

Prof. Dr. Mario Di Gioacchino
Prof. Dr. Sebastiano Gangemi
Prof. Dr. Erminia Ridolo
Dr. Giovanni Paoletti
Dr. Antonio G. Solimando
Collection Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • T cells and B cells
  • regulatory T cells
  • NK cells
  • antigen-presenting cells
  • mast cells
  • eosinophils
  • complement
  • inflammation
  • cytokines
  • immunosenescence
  • immuno-oncology


  • anaphylaxis
    hypereosinophilic syndrome
  • asthma
  • rhinoconjunctivitis
  • rhinosinusitis
  • atopic dermatitis
  • urticaria
  • angioedema
  • food allergy
  • innate and acquired immunedeficiency
  • systemic and organ-specific autoimmune diseases
  • immunotherapy
  • biologics

Published Papers

This collection is now open for submission.
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