Special Issue "Autophagy in Kidney Homeostasis and Disease"
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 8348
Over the past two and a half decades, the exploration of key genes that are essential for autophagy, originally identified in yeast, has revealed that autophagy maintains vital functions through the elimination of functionless cellular constituents by lysosomes. In the kidneys, this housecleaning pathway preserves the homeostasis from the glomerular tuft along the entire nephron, thereby sustaining many fundamental processes from glomerular filtration barrier selectivity to tubular transport. The dysregulation of this fundamental pathway disrupts cellular and physiological homeostasis, and may ultimately lead to chronic kidney diseases of varied aetiologias, including diabetic kidney disease, focal segmental glomerulosclerosis, and polycystic kidney disease. However, questions remain about the signaling circuitries controlling autophagy in different types of kidney cells and across the spectrum of kidney disease.
This Special Issue aims to highlight the recent advances in our understanding of the complex regulation of autophagy and its biological functions in the context of kidney homeostasis, disease, and pharmacological intervention. We encourage you to submit research articles as well as review articles that investigate the physiological role of autophagy in kidney cells and how its perturbation leads to kidney disease, including new therapeutics and methods for measuring different autophagic forms.
Dr. Alessandro Luciani
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- chaperone-mediated autophagy
- organelle quality control
- oxidative stress
- kidney cells
- kidney disease