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Special Issue "Developmental Origins of Kidney Disease and Targeted Therapeutics"
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: closed (15 May 2023) | Viewed by 6902
Special Issue Editors
Interests: development; pattern formation; organogenesis; regeneration; stem cell biology; nephrogenesis; hematopoiesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
During vertebrate embryogenesis, kidneys contain progenitor populations which fuel the formation of nephrons and the collecting duct network. Alterations in these events can lead to various renal malformations. The formation of mature nephrons is particularly critical, as these structures are the core functional units of the kidney that cleanse the blood and maintain fluid homeostasis. The absence or perturbation of nephrogenesis can cause congenital birth defects. Postnatally, nephron damage can initiate devastating acute and/or chronic conditions. Nephron composition is complex where over a dozen differentiated cell types are organized in distinct regions, each performing specialized physiological roles. Single-cell sequencing technologies have aided in characterizing and tracking these nephron cell types during kidney ontogeny and disease progression. Furthermore, the ability to grow kidney organoids has provided a new opportunity to study nephrogenesis, model human diseases, and screen compounds in a personalized manner. Advancing our understanding of nephron development and disease dynamics will facilitate the identification of key biomarkers and breakthroughs in renal therapeutics. This Special Issue will provide an open access opportunity to publish research and review articles related to the in vivo and in vitro development of nephrons.
Dr. Rebecca A. Wingert
Dr. Brooke Chambers
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- renal stem cell
- acute kidney injury
- chronic kidney disease