Special Issue "The Role of Cellular Organelles in Neurodevelopmental and Neurological Disorders"

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".

Deadline for manuscript submissions: 1 December 2023 | Viewed by 161

Special Issue Editor

CASE School of Medicine, Cleveland, OH, USA
Interests: mitochondrial fragmentation; mitochondria-ER contacts; neurological disorders; RNA m6A modification; neuron-glia crosstalk

Special Issue Information

Dear Colleagues,

The role of the cellular organelles in neurodevelopmental and neurological disorders has received increasing attention over the past few years. These disorders are common disabilities primarily associated with the functioning of the brain and likely result from a combination of genetic and environmental risk factors. Dysfunctions of the cellular organelles such as mitochondria, endoplasmic reticulum (ER), lysosomes, endosomes, Golgi apparatus, ribosomes, and autophagosome play important roles in multiple brain disorders. However, the way that these organelle dysfunctions contribute to disease progressions in different brain cell types remains to be elucidated. Additionally, crucial physiological functions of cells are regulated by complex organelle crosstalk including mitochondrial–ER contacts (MERCs), mitochondria–endolysosomal systems, autophagy–lysosomal pathways, and exosome–autophagy pathways, etc. It’s still largely unknown how the dysfunction of organelle crosstalk regulates the progression of these various brain disorders.

This Special Issue provides a platform for original research manuscripts and prospective reviews on the underlying pathogenic mechanisms of the organelle dysfunctions and the potential therapeutic strategies in the neurodevelopmental and neurological disorders. 

Dr. Fanpeng Zhao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • neurodevelopmental disorders
  • neurological disorders
  • neurodegeneration
  • organelle crosstalk
  • mitochondrial–ER contacts
  • endolysosomal system
  • autophagy

Published Papers

This special issue is now open for submission.
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