Special Issue "Regulation and Function of Cardiac Ion Channels"
Deadline for manuscript submissions: closed (15 July 2021) | Viewed by 12122
Interests: ion channels; long QT; cell signaling; cardiac arrhythmias
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Precise ion channel function and regulation are necessary for normal cardiac function. Cardiac channel expression, localization, and regulation are fine tuned to modify cardiomyocyte electrical properties to the required needs. Channel dysregulation in response to disease, inherited mutations, drugs, and hormonal imbalances can cause electrocardiogram (ECG) changes leading to cardiac arrhythmias and sudden death.
This Special Issue will focus on novel molecular mechanisms of cardiac ion channel regulation, and will specifically deal with pathological cardiac channel dysregulation and its consequences for cardiac rhythm and arrhythmia susceptibility. Manuscripts dealing with dysregulation due to common and rare genetic variants of ion channels, novel regulatory subunits, and novel mechanims that disrupt channel trafficking, expression, or transcription will be of interest. We will also focus on non-traditional animal, cell, and computational models and new methods for investigating cardiac ion channel dysregulation.
We intend to include in this Special Issue articles that shed light on new avenues to investigate arrhythmogenesis at a molecular and genetic level and highlight new methods that support these investigations.
Dr. Coeli M. Lopes
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- heart failure
- QT-prolonging drugs