Special Issue "Liver Injury and Regeneration: From Basic to Translational Research"
Deadline for manuscript submissions: 30 November 2023 | Viewed by 14138
The liver is the largest internal organ of our body, and plays a central role in all metabolic processes. However, it is constantly exposed to a plethora of insults, including hepatitis virus, alcohol, high-fat diet and drugs/chemicals, which can act either individually or in combination to cause liver injury. Interestingly, the liver has a unique and remarkable ability to regenerate, a phenomenon that was recognized more than two millennia ago in the myth of Prometheus from the ancient Greeks. In acute and transient injury caused by insults like partial hepatectomy or accidental acetaminophen overdose, the liver mass and function can be restored within a week by proliferation and remodeling of the remaining cells. However, in many chronic conditions, such as prolonged alcohol abuse, non-alcoholic fatty liver disease (NAFLD), viral hepatitis infection, as well as autoimmune and genetic disorders, the injury can persist and the regenerative capacity of the liver eventually becomes impaired, resulting in progressive deterioration of liver functions and eventually hepatic scarring and cirrhosis. Therefore, the outcome of liver injury is also dictated by the effectiveness of liver regeneration and repair. In this Special Issue, we invite you to improve the current knowledge of any aspect of cellular and molecular mechanisms of liver injury and regeneration with original research articles, and to summarize the current state of this intriguing field with compelling reviews. Manuscripts providing translational value will be particularly welcome.
Dr. Kuo Du
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- liver injury
- liver regeneration
- liver repair
- liver diseases