Tooth-Related Stem Cells and Regenerative Medicine

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".

Deadline for manuscript submissions: 15 June 2024 | Viewed by 103

Special Issue Editors

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Guest Editor
Department of Oral Medicine and Stomatology, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan
Interests: stem cell biology (iPS cells, mesenchymal stem cells, dental-pulp-derived stem cells) and regenerative medicine including tissue engineering; wound healing; cell biology for melatonin; cell biology for leptin; tooth development; cell biology of grapefruit seed extract; cell biology of candida species; cell biology of oral cancer; photodynamic diagnosis and treatment; photoimmunotherapy
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Guest Editor
Department of Oral Anatomy, School of Dentistry, Aichi-Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya 464-8650, Aichi, Japan
Interests: periodontal ligament; stem cell; tooth germs; tooth regeneration; dental follicle cells; stem cell biology; histogenesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue entitled “Tooth-Related Stem Cells and Regenerative Medicine” is the second edition of Dental Pulp Stem Cells and Regenerative Medicine, which previously published 10 papers.

Dental pulp stem cells (DPSCs), a type of mesenchymal stem cells isolated from dental pulp, have higher cell proliferative ability than and mostly comparable differentiation capacity to other types of stem cells, such as bone-marrow-derived mesenchymal stem cells and adipose-tissue-derived mesenchymal stem cells. Moreover, DPSCs are easy to collect without severe impairment in their donor site because they are easily obtained from extracted teeth. Furthermore, it has been suggested in animal studies that DPSCs may be efficacious even for the treatment of spinal cord injury, Alzheimer’s disease, Parkinson’s disease, and so forth. Consequently, DPSCs are considered to be a good, realistic, and prospective candidate for cell sources for various cell-based therapies including regenerative medicine for damaged organs and tissues.

We invite you to contribute to this Special Issue of Cells in the form of original research articles and reviews on all aspects related to the theme of “Dental Pulp Stem Cells and Regenerative Medicine”. Expert articles describing cellular and/or molecular aspects of the proliferation and/or differentiation of DPSCs are highly welcome. Methodological articles describing the propagation and differentiation induction of DPSCs are also welcomed. Relevant topics include, but are not limited to:

  • Mesenchymal stem cells;
  • Neural crest cells;
  • Bone marrow;
  • Adipose tissue;
  • Cell proliferation;
  • Cell differentiation;
  • Signal transduction;
  • Extracellular matrix;
  • Growth factors;
  • Cell culture;
  • Scaffolds;
  • Cell sheets;
  • Preservation;
  • Transplantation;
  • Bone;
  • Dentin;
  • Cartilage;
  • Tooth;
  • Tissue engineering.

Prof. Dr. Kazuhito Satomura
Dr. Masaki Honda
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • mesenchymal stem cells
  • neural crest cells
  • bone marrow
  • adipose tissue
  • cell proliferation
  • cell differentiation
  • signal transduction
  • extracellular matrix
  • growth factors
  • cell culture
  • scaffolds
  • cell sheets
  • preservation
  • transplantation
  • bone
  • dentin
  • cartilage
  • tooth
  • tissue engineering

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Published Papers

This special issue is now open for submission.
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