Special Issue "Autophagy and Apoptosis in Skeletal Muscle"
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 2513
Interests: apoptosis; muscular dystrophy; immune system; sphingolipids
Interests: mitochondria; skeletal muscle; autophagy; muscular dystrophy; metabolism
Interests: mitochondria; autophagy; extracellular matrix; electron microscopy
Special Issues, Collections and Topics in MDPI journals
Autophagy and apoptosis are two key processes for maintaining cellular homeostasis in tissues and are regulated through various and highly coordinated signal transduction mechanisms.
Also in skeletal muscle, a plastic tissue that reacts and adjusts to several physiological and pathological conditions, autophagy and apoptosis are finely tuned and may have both beneficial and harmful effects, depending on the condition of the tissue and their level of activation. For instance, both processes may impinge the fate of skeletal muscle after damage and contribute to the pathogenesis of diseases such as myopathies and muscular dystrophies.
In this Special Issue, we will collect studies focused on the role of autophagy and/or apoptosis in skeletal muscle homeostasis, injury, and repair and in skeletal muscle diseases such as myopathies, muscular dystrophies, atrophy, and sarcopenia, also focusing on the interaction with immune system cells. Furthermore, we encourage research on mitophagy and mitochondrial apoptotic signaling in skeletal muscle pathophysiology, due to mitochondria’s critical role in determining cell life and death. Finally, we aim to gather studies exploring the possibility of targeting autophagy/apoptosis as novel therapeutic strategies for the treatment of muscle diseases. Original research papers, review articles, communications, perspectives, and commentaries are welcome.
Dr. Cristiana Perrotta
Dr. Clara De Palma
Dr. Claudia Moscheni
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- skeletal muscle
- cell signaling
- immune system
- therapeutic strategies