Special Issue "Cellular and Molecular Mechanism of Neuroimmunological Diseases"
Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 1331
The impact of the immune system on the development of neurological diseases such as Multiple Sclerosis and Myasthenia Gravis has long been known. What has more recently become clear is the critical role of the immune system in disease progression in a wide range of neurological diseases that are not identified as classical neuroimmunological diseases. For example, conditions such as Alzheimer’s disease, Parkinson’s disease, ALS, stroke and neuropathic pain all have a significant engagement of the immune system. In most conditions the impact of the immune system is considered to be detrimental to recovery, however in certain circumstances such as where cellular debris inhibits recovery, removal of debris by cells of the immune system may actually enhance recovery. Understanding such interplay between the systemic and innate immune systems with cells of the nervous system is critical for harnessing the positive and mitigating the negative effects of such interactions.
The aim of this special issue is to highlight the similarities and differences in how neuroimmune interactions contribute to the pathogenesis of a range of neurological conditions with the hope that such knowledge will trigger new therapeutic directions.
Prof. Dr. Robert H. Miller
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- neurodegenerative diseases
- neuro-immune interactions
- CNS injury
- neural repair