Special Issue "Neuroinflammation in Developmental Brain Diseases"

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".

Deadline for manuscript submissions: 7 July 2025 | Viewed by 267

Special Issue Editors

Department of Pediatrics PRI, University of Louisville Health Sciences Center, Louisville, KY, USA
Interests: inflammation; oxidative injury; neuroinflammation; neurodevelopment; hypoxia ischemia; endothelial injury
Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY, USA
Interests: oligodendrocytes development; myelination; neuron-glia communication; developmental diseases
1. Department of Pediatrics, Pediatric Research Institute, University of Louisville School of Medicine, Donald Baxter Building, Suite 321B, 570 S. Preston Street, Louisville, KY 40202, USA
2. Department of Neurology, University of Louisville School of Medicine, Louisville, KY 40202, USA
3. Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202, USA
Interests: autism; neurodevelopmental disorders; epilepsy; cannabinoids; axon guidance; genetics

Special Issue Information

Dear Colleagues,

Several neurodevelopmental disorders such as autism spectrum disorders, epilepsy, intellectual disability, attention deficit/hyperactivity disorders, communication disorders, cerebral palsy or schizophrenia have been linked to early life neuroinflammation and oxidative stress. Neuroinflammation is also a critical component of the CNS immunity. Persistent of this process becomes damaging, and ultimately perturbing cytokine-mediated normal immunity. Brain oxidative stress and uncontrolled microglial activation may result in immune dysfunction, vascular inflammation, disrupting the blood brain barrier, recruiting inflammatory cells and further escalating the inflammatory process and impacting CNS development. These processes have been shown to contribute to cognitive impairment, autism, attention deficit hyperactivity disorders, anxiety and depression. We invite original research articles, reviews, or shorter perspective articles on all aspects related to the theme of this special issue entitled: “Neuroinflammation in Developmental Brain Diseases”. Expert articles describing mechanistic, functional, cellular, biochemical, or general aspects of neuroinflammation and its consequences on CNS development and diseases are highly welcome.

Dr. Evelyne Gozal
Dr. Jun Cai
Prof. Dr. Gregory Neal Barnes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • neuroinflammation
  • endothelial injury
  • blood brain barrier
  • microglia
  • immune dysfunction
  • oxidative stress
  • autism spectrum disorders
  • epilepsy
  • cerebral palsy
  • schizophrenia
  • neurodevelopment
  • neurovascular brain signaling
  • inflammatory cytokines
  • immune cells

Published Papers

This special issue is now open for submission.
Back to TopTop