Special Issue "Profibrotic Mediators in Hypertrophic Scarring"
Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 1132
The process and mechanism of physiological skin wound healing have been extensively studied and are well understood. However, the complications caused by abnormal wound healing, such as chronic wounds，unhealing wounds, and scar or keloid formation have not been effectively prevented and treated, which are still the medical problems that endanger people's body and psychological health, and pose a significant medical expense every year. As a common complication of burns, hypertrophic scars result from fibrotic wound healing after burn injuries. Both cellular and molecular aspects participate in fibrotic wound healing. Given the extracellular matrix-rich structure of the skin, comprehensive study on structural protein molecules, growth factors, chemokines, as well as other cytokines may be an important breakthrough to find the profibrotic mediators, which construct a fibrotic microenvironment, together with cells, contributing to hypertrophic scarring. Exploring an effective therapeutic strategy on hypertrophic scars is necessary to improve people’s health and life quality. We welcome your submissions of original research and review articles with this specific topic.
Therefore, welcome to contribute this Special Issue.
Dr. Jie Ding
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- fibrotic wound healing
- hypertrophic scars
- profibrotic mediators