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17 March 2023
Cells | Issue Cover Articles in 2022

The articles below have been selected as 2022 Issue Cover Articles by the Editorial Office of Cells (ISSN: 2073-4409). These articles are from multiple fields within the scope of Cells, and we hope they can provide insights and references for scholars in related fields.

1. “Epithelial and Neural Cadherin in Mammalian Fertilization: Studies in the Mouse Model”
by Gustavo Luis Verón, María Florencia Veiga, Mónica Cameo, Clara Isabel Marín-Briggiler and Mónica Hebe Vazquez-Levin
Cells 2022, 11(1), 102; https://doi.org/10.3390/cells11010102
Available online: https://www.mdpi.com/2073-4409/11/1/102

2. “Transient Exposure of Endothelial Cells to Doxorubicin Leads to Long-Lasting Vascular Endothelial Growth Factor Receptor 2 Downregulation”
by Silvia Graziani, Luca Scorrano and Giovanna Pontarin
Cells 2022, 11(2), 210; https://doi.org/10.3390/cells11020210
Available online: https://www.mdpi.com/2073-4409/11/2/210

3. “LEAP-2 Counteracts Ghrelin-Induced Food Intake in a Nutrient, Growth Hormone and Age Independent Manner”
by Javier Lugilde, Sabela Casado, Daniel Beiroa, Juan Cuñarro, Montserrat Garcia-Lavandeira, Clara V. Álvarez, Rubén Nogueiras, Carlos Diéguez and Sulay Tovar
Cells 2022, 11(3), 324; https://doi.org/10.3390/cells11030324
Available online: https://www.mdpi.com/2073-4409/11/3/324

4. “Radon Improves Clinical Response in an Animal Model of Rheumatoid Arthritis Accompanied by Increased Numbers of Peripheral Blood B Cells and Interleukin-5 Concentration”
by Lisa Deloch, Stephanie Hehlgans, Michael Rückert, Andreas Maier, Annika Hinrichs, Ann-Sophie Flohr, Denise Eckert, Thomas Weissmann, Michaela Seeling and Falk Nimmerjahn et al.
Cells 2022, 11(4), 689; https://doi.org/10.3390/cells11040689
Available online: https://www.mdpi.com/2073-4409/11/4/689

5. “CRISPR/Cas9-Mediated Models of Retinitis Pigmentosa Reveal Differential Proliferative Response of Müller Cells between Xenopus laevis and Xenopus tropicalis
by Karine Parain, Sophie Lourdel, Alicia Donval, Albert Chesneau, Caroline Borday, Odile Bronchain, Morgane Locker and Muriel Perron
Cells 2022, 11(5), 807; https://doi.org/10.3390/cells11050807
Available online: https://www.mdpi.com/2073-4409/11/5/807

6. “Biallelic Variants in ENDOG Associated with Mitochondrial Myopathy and Multiple mtDNA Deletions”
by Alessia Nasca, Andrea Legati, Megi Meneri, Melisa Emel Ermert, Chiara Frascarelli, Nadia Zanetti, Manuela Garbellini, Giacomo Pietro Comi, Alessia Catania and Costanza Lamperti et al.
Cells 2022, 11(6), 974; https://doi.org/10.3390/cells11060974
Available online: https://www.mdpi.com/2073-4409/11/6/974

7. “Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells”
by Piper A. Robida, Clayton H. Rische, Netali Ben-Baruch Morgenstern, Rethavathi Janarthanam, Yun Cao, Rebecca A. Krier-Burris, Wouter Korver, Alan Xu, Thuy Luu and Julia Schanin et al.
Cells 2022, 11(7), 1138; https://doi.org/10.3390/cells11071138
Available online: https://www.mdpi.com/2073-4409/11/7/1138

8. “N-VEGF, the Autoregulatory Arm of VEGF-A”
by Marina Katsman, Aviva Azriel, Guy Horev, Yitzhak Reizel and Ben-Zion Levi
Cells 2022, 11(8), 1289; https://doi.org/10.3390/cells11081289
Available online: https://www.mdpi.com/2073-4409/11/8/1289

9. “SARS-CoV-2 Infection of Human Ovarian Cells: A Potential Negative Impact on Female Fertility”
by Francesca P. Luongo, Filippo Dragoni, Adele Boccuto, Eugenio Paccagnini, Mariangela Gentile, Tamara Canosi, Giuseppe Morgante, Alice Luddi, Maurizio Zazzi, Ilaria Vicenti et al.
Cells 2022, 11(9), 1431; https://doi.org/10.3390/cells11091431
Available online: https://www.mdpi.com/2073-4409/11/9/1431

10. “SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta”
by Marco Kirchenwitz, Stephanie Stahnke, Silvia Prettin, Malgorzata Borowiak, Laura Menke, Christian Sieben, Carmen Birchmeier, Klemens Rottner, Theresia E. B. Stradal and Anika Steffen
Cells 2022, 11(10), 1648; https://doi.org/10.3390/cells11101648
Available online: https://www.mdpi.com/2073-4409/11/10/1648

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11. “Cigarette Smoke Extract Disturbs Mitochondria-Regulated Airway Epithelial Cell Responses to Pneumococci”
by Mahyar Aghapour, Christy B. M. Tulen, Mohsen Abdi Sarabi, Sönke Weinert, Mathias Müsken, Borna Relja, Frederik-Jan van Schooten, Andreas Jeron, Rüdiger Braun-Dullaeus and Alexander H. Remels et al.
Cells 2022, 11(11), 1771; https://doi.org/10.3390/cells11111771
Available online: https://www.mdpi.com/2073-4409/11/11/1771

12. “Nuclear Transporter IPO13 Is Central to Efficient Neuronal Differentiation”
by Katarzyna A. Gajewska, John M. Haynes and David A. Jans
Cells 2022, 11(12), 1904; https://doi.org/10.3390/cells11121904
Available online: https://www.mdpi.com/2073-4409/11/12/1904

13. “PKC-Mediated Orai1 Channel Phosphorylation Modulates Ca2+ Signaling in HeLa Cells”
by Ericka Martínez-Martínez, Víctor Hugo Sánchez-Vázquez, Daniel León-Aparicio, Jose Sanchez-Collado, Martín-Leonardo Gallegos-Gómez, Juan A. Rosado, Juan M. Arias and Agustin Guerrero-Hernández
Cells 2022, 11(13), 2037; https://doi.org/10.3390/cells11132037
Available online: https://www.mdpi.com/2073-4409/11/13/2037

14. “CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints”
by Martin Böttcher, Romy Böttcher-Loschinski, Sascha Kahlfuss, Michael Aigner, Andreas Gießl, Andreas Mackensen, Ursula Schlötzer-Schrehardt, Thomas Tüting, Heiko Bruns and Dimitrios Mougiakakos
Cells 2022, 11(14), 2176; https://doi.org/10.3390/cells11142176
Available online: https://www.mdpi.com/2073-4409/11/14/2176

15. “Hyperoxaluria Induces Endothelial Dysfunction in Preglomerular Arteries: Involvement of Oxidative Stress”
by Javier Saenz-Medina, Mercedes Muñoz, Claudia Rodriguez, Cristina Contreras, Ana Sánchez, María José Coronado, Elvira Ramil, Martin Santos, Joaquín Carballido and Dolores Prieto
Cells 2022, 11(15), 2306; https://doi.org/10.3390/cells11152306
Available online: https://www.mdpi.com/2073-4409/11/15/2306

16. “USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation”
by Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire and Veronique A. J. Smits
Cells 2022, 11(16), 2492; https://doi.org/10.3390/cells11162492
Available online: https://www.mdpi.com/2073-4409/11/16/2492

17. “The CaMKII/MLC1 Axis Confers Ca2+-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes”
by Maria Stefania Brignone, Angela Lanciotti, Antonio Michelucci, Cinzia Mallozzi, Serena Camerini, Luigi Catacuzzeno, Luigi Sforna, Martino Caramia, Maria Cristina D’Adamo and Marina Ceccarini et al.
Cells 2022, 11(17), 2656; https://doi.org/10.3390/cells11172656
Available online: https://www.mdpi.com/2073-4409/11/17/2656

18. “The ABA-LANCL1/2 Hormone-Receptors System Protects H9c2 Cardiomyocytes from Hypoxia-Induced Mitochondrial Injury via an AMPK- and NO-Mediated Mechanism”
by Sonia Spinelli, Lucrezia Guida, Tiziana Vigliarolo, Mario Passalacqua, Giulia Begani, Mirko Magnone, Laura Sturla, Andrea Benzi, Pietro Ameri, Edoardo Lazzarini et al.
Cells 2022, 11(18), 2888; https://doi.org/10.3390/cells11182888
Available online: https://www.mdpi.com/2073-4409/11/18/2888

19. “Brain Endothelial Cells in Contrary to the Aortic Do Not Transport but Degrade Low-Density Lipoproteins via Both LDLR and ALK1”
by Sofia Kakava, Eveline Schlumpf, Grigorios Panteloglou, Flavia Tellenbach, Arnold von Eckardstein and Jerome Robert
Cells 2022, 11(19), 3044; https://doi.org/10.3390/cells11193044
Available online: https://www.mdpi.com/2073-4409/11/19/3044

20. “Decreased Oligodendrocyte Number in Hippocampal Subfield CA4 in Schizophrenia: A Replication Study”
by Andrea Schmitt, Laura Tatsch, Alisa Vollhardt, Thomas Schneider-Axmann, Florian J. Raabe, Lukas Roell, Helmut Heinsen, Patrick R. Hof, Peter Falkai and Christoph Schmitz
Cells 2022, 11(20), 3242; https://doi.org/10.3390/cells11203242
Availble online: https://www.mdpi.com/2073-4409/11/20/3242

21. “Chromatin Accessibility and Transcriptional Differences in Human Stem Cell-Derived Early-Stage Retinal Organoids
by Melissa K. Jones, Devansh Agarwal, Kevin W. Mazo, Manan Chopra, Shawna L. Jurlina, Nicholas Dash, Qianlan Xu, Anna R. Ogata, Melissa Chow and Alex D. Hill et al.
Cells 2022, 11(21), 3412; https://doi.org/10.3390/cells11213412
Available online: https://www.mdpi.com/2073-4409/11/21/3412

22. “Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model
by Maeve Boyce, Ying Xin, Olivia Chowdhury, Peng Shang, Haitao Liu, Victoria Koontz, Anastasia Strizhakova, Mihir Nemani, Stacey Hose, J and Samuel Zigler, Jr., et al.
Cells 2022, 11(22), 3535; https://doi.org/10.3390/cells11223535
Available online: https://www.mdpi.com/2073-4409/11/22/3535

23. “Extracellular Vesicles from Human Umbilical Cord-Derived MSCs Affect Vessel Formation In Vitro and Promote VEGFR2-Mediated Cell Survival
by Ana Muñiz-García, Bettina Wilm, Patricia Murray and Michael J. Cross
Cells 2022, 11(23), 3750; https://doi.org/10.3390/cells11233750
Available online: https://www.mdpi.com/2073-4409/11/23/3750

24. “Polymerized Laminin-521: A Feasible Substrate for Expanding Induced Pluripotent Stem Cells at a Low Protein Concentration
by Fernanda C. P. Mesquita, Eliel S. Leite, Jacquelynn Morrissey, Catarina Freitas, Tatiana Coelho-Sampaio and Camila Hochman-Mendez
Cells 2022, 11(24), 3955; https://doi.org/10.3390/cells11243955
Available online: https://www.mdpi.com/2073-4409/11/24/3955

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