New Trends in Asymmetric Catalysis: Green and Sustainable Catalysts

A special issue of Catalysts (ISSN 2073-4344). This special issue belongs to the section "Catalysis in Organic and Polymer Chemistry".

Deadline for manuscript submissions: closed (1 December 2023) | Viewed by 3308

Special Issue Editors


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Guest Editor
Dipartimento di Chimica e Biologia "Adolfo Zambelli" DCB, Università di Salerno, Salerno, Italy
Interests: stereoselective organocatalyzed and metal-catalyzed reactions; enantioselective synthesis; phase–transfer catalysis; macrocyclic catalysts; synthesis and applications of cyclic peptoids
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Dipartimento di Chimica e Biologia "Adolfo Zambelli" DCB, Università di Salerno, Salerno, Italy
Interests: synthesis of cyclic peptoids and their derivatives; phase-transfer catalysts; asymmetric synthesis; macrocyclic catalysts; biological applications; MRI contrast agents
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

After the first successful Special Issue focused on asymmetric catalysis available here, we are now pleased to propose the second edition titled “New Trends in Asymmetric Catalysis: Green and Sustainable Catalysts”.

The constant demand for enantiopure or enantioenriched chiral molecules in diverse industrial areas, such as the pharmaceutical, agrochemical, cosmetic, food chemistry and material science, lies at the base of the extraordinary development of asymmetric synthesis, and in particular of asymmetric catalysis, over the past few decades. However, metal-catalysis, organocatalysis, and biocatalysis, the three main strategies of asymmetric catalysis, are still continuously expanding today and tackling ever new challenges.

Taking into account the evolving requirements about environmental issues, green chemistry has been receiving increasing attention by academic and industrial research. In particular, organic synthesis laboratories and pharmaceutical industries are constantly engaged in developing enantioselective green processes involving reduced amount of hazardous reagents and solvents, fewer purification steps and low energetic consumption. In this context, many efforts are devoted to the employment of organocatalysts or non-toxic metal catalysts, reusable catalysts, multi-step reactions and continuous flow chemical processes. In addition, the need to exploit renewable sources of energy and materials stimulated the rational design of novel ligands and organocatalysts from biomass feedstocks and the increasing use of alternative forms of energy, leading to the development of novel strategies such as asymmetric photocatalysis and electrosynthesis.

This second edition of the Special Issue on New Trends in Asymmetric Catalysis aims to cover recent updates in this timeless topic, with a special focus on green and sustainability issues. Research articles, short communications, brief reports, and review papers on this topic are welcomed.

Dr. Giorgio Della Sala
Dr. Rosaria Schettini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chiral catalysts
  • enantioselectivity
  • renewable chiral catalysts
  • asymmetric metal catalysis
  • asymmetric phase
  • transfer catalysis
  • enantioselective enzyme-catalyzed reactions
  • kinetic resolution
  • biocatalysis
  • photocatalysis
  • supported chiral catalysts
  • sustainable catalysts
  • bifunctional catalysis

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Published Papers (2 papers)

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Review

33 pages, 6716 KiB  
Review
Asymmetric Dual Enamine Catalysis/Hydrogen Bonding Activation
by Efraím Reyes, Liher Prieto, Uxue Uria, Luisa Carrillo and Jose L. Vicario
Catalysts 2023, 13(7), 1091; https://doi.org/10.3390/catal13071091 - 11 Jul 2023
Viewed by 1216
Abstract
Asymmetric enamine base activation of carbonyl compounds is a well-known and widely used strategy for providing functionalization of organic compounds in an efficient way. The use of solely organic substances, which in most cases are commercially available primary or secondary amines that are [...] Read more.
Asymmetric enamine base activation of carbonyl compounds is a well-known and widely used strategy for providing functionalization of organic compounds in an efficient way. The use of solely organic substances, which in most cases are commercially available primary or secondary amines that are easy to obtain, avoids the use of hazardous substances or metal traces, making this type of catalysis a highly convenient methodology from a sustainable point of view. In many cases, the reactivity or the stereoselectivity obtained is far from being a practical and advantageous strategy; this can be improved by using a hydrogen bonding co-catalyst that can help during the activation of one species or by using a bifunctional catalyst that can direct the approximation of reagents during the reaction outcome. In this review, we describe the most efficient methodologies that make use of a dual activation of reagents for performing α-functionalization (enamine activation) or remote functionalization (such as dienamine or trienamine activation) of carbonyl compounds. Full article
(This article belongs to the Special Issue New Trends in Asymmetric Catalysis: Green and Sustainable Catalysts)
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20 pages, 9564 KiB  
Review
Recent Advances in Enantioselective Catalytic Electrochemical Organic Transformations
by Fabrizio Medici, Simonetta Resta, Stefano Andolina and Maurizio Benaglia
Catalysts 2023, 13(6), 944; https://doi.org/10.3390/catal13060944 - 28 May 2023
Cited by 3 | Viewed by 1683
Abstract
Different approaches can be undertaken to realise a stereoselective electrochemical synthesis. Significant contributions to enantioselective electrochemical organic synthesis have been reported and largely reviewed in recent years. However, the development of general strategies for the electrochemical enantiocontrol of a transformation still presents considerable [...] Read more.
Different approaches can be undertaken to realise a stereoselective electrochemical synthesis. Significant contributions to enantioselective electrochemical organic synthesis have been reported and largely reviewed in recent years. However, the development of general strategies for the electrochemical enantiocontrol of a transformation still presents considerable challenges; in particular, relatively few contributions of highly enantioselective catalytic electrochemical reactions have been reported to date. In this review article, the most recent examples of asymmetric electrochemical catalysis are discussed. The article is organised by the three types of enantioselective catalysis: metal-based catalysis, organocatalysis and biocatalysis; in each section, the most significant and recent advances are presented and discussed. Full article
(This article belongs to the Special Issue New Trends in Asymmetric Catalysis: Green and Sustainable Catalysts)
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