Special Issue "New Approaches in Modulating Transcription Factors for Cancer Therapy"
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 1911
Special Issue Editor
Interests: breast and ovarian cancer; drug discovery; transcription factors; metastasis; chemoresistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Aberrant expression or activation of transcription factors occurs in most cancers. Transcription factors are often the convergence point from many upstream signals that may be mutated or overexpressed in cancer, leading to inappropriate expression or constitutive activation. These transcription factors often promote the pathogenic features of cancer, and most cancers become addicted to the constitutive activity of the transcription factor. However, most transcription factors are often difficult to target, since many of them lack a ligand binding or active site. In this Special Issue, we will focus on new treatment modalities that target transcription factors in cancer. These strategies may include new small molecule inhibitors, CRISPR-based strategies, degrader technology, peptide mimetics, or others.
Dr. Sarah Walker
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- transcription factors
- cancer
- treatment
- degraders
- inhibitors
