Recent Advances in Particle Therapy for Cancers
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 4482
Special Issue Editors
Interests: particle therapy; computational medical physics
Special Issue Information
Dear Colleagues,
Particle therapy was first used at the Lawrence Berkeley National Laboratory more than 50 years ago. After that program closed, particle therapy moved to Japan in 1994 and later Germany in 2002. Currently, there are 13 operational facilities, with a few more under construction.
In this Special Issue, we will focus on three key aspects of particle therapy:
- Physics and technology: recent advancements in technology, including but not limited to accelerators, imaging, detectors, and computational capabilities, and the advancements they have led to in particle therapy;
- Radiation biology: the radiobiological advantage of particle therapy, which comes from its high LET and leads to direct and clustered DNA damage and a large relative biological effectiveness (RBE). In addition, specific biological mechanisms that make particle therapy especially suitable for tumors that are radiation-resistant and/or hypoxic and which mean that it has great potential for inducing therapeutic immune responses;
- Clinical outcomes: knowledge stemming from the approximately 50,000 patients who have been treated with CIRT in the past three decades, as well as the Phase I/II trials that have been carried out in Japan and Europe over the years and which show negligible toxicity while simultaneously showing great tumor control for a wide variety of treatment sites, including but not limited to bone and soft tissue sarcomas, adenocarcinoma, and malignant melanoma.
Dr. Chris J. Beltran
Dr. Keith Furutani
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- radiation biology
- radiation oncology
- computational biology
- high LET
- microdosimetry
- Monte Carlo
- biological modeling
- in silico commissioning beam performance
- medical physics
- quality assurance/control
- realtime imaging
- cone beam
- computed tomography
- novel beam delivery
