Special Issue "Malignant Pleural Mesothelioma (MPM)"
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 20392
Interests: cancer; metastases; mesothelioma; targeted therapies; genetics
Special Issues, Collections and Topics in MDPI journals
Malignant pleural mesothelioma (MPM) is a fatal asbestos-related malignancy originating in the mesothelial cells of the pleura. Whereas MPM incidence in USA has remained stable at 3000 deaths/year, rates in Europe and Japan are projected to peak in the coming years. Modern targeted therapies have so far failed in MPM. Growing evidence suggests that the unique tumor microenvironment is involved in disease onset and in inducing resistance to conventional therapies. Overall, this has led to MPM being listed as an orphan disease by the European Union (EU). The need for new therapies is therefore urgent. The aim of this Special Issue is thus to collect the state-of-the-art about the biomolecular asset of MPM, the novel omics approaches to understand, stage, and treat the disease as well as the more recent immunologically centered therapeutic regimens.
Dr. Giulia M Stella
Dr. Chandra Bortolotto
Manuscript Submission Information
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- targeted therapies