Special Issue "Molecular Profiling, Detection, and Therapy of Squamous Cell Carcinomas"
Deadline for manuscript submissions: closed (30 October 2023) | Viewed by 4972
Interests: squamous cell carcinoma of the skin; tumor biology; tumor microenvironment; cancer (immune) therapy; contribution of microbiome to cancer formation
Interests: squamous cell carcinoma of the skin; tumor biology; cancer therapy; contribution of microbiome to cancer formation
Interests: squamous cell carcinoma of the skin; tumor biology; tumor microenvironment; tumor detection and early diagnosis; tumor biomarkers
Squamous cell carcinoma (SCCs) constitutes one of the most prevalent solid cancers and is a major cause of deaths worldwide. SCCs comprise a wide range of tumors that originate in different organs and are classified according to their site of development, i.e., skin, head and neck, mouth, oesophagus, lung, cervix, prostate, bladder, etc. Genetic mutations, epigenetic modifications, altered gene expression and a supportive tumor microenvironment, featuring changes in epithelial, stromal, immune and endothelial components, drive the development and progression of the disease. Addressing various aspects of tumor heterogeneity is critical to the development of new molecular markers, as well as effective therapeutic approaches. Recent advances in various “omics” technologies now enable deeper insight into the complex cellular heterogeneity and signaling cascades underlying these tumors. For this Special Issue, we welcome original research articles and reviews that focus on (but not exclusively): profiling of SCCs that help unravel the complex molecular mechanisms underlying tumor development and progression; biomarkers that will improve detection, diagnosis and prediction of therapeutic success; and immune, cell or gene therapeutic approaches to combat SCCs. We also encourage the submission of scientific work that employs innovative technologies to investigate these aspects.
We look forward to your valued contributions to this special issue.
Dr. Josefina Pinon Hofbauer
Dr. Christina Guttmann-Gruber
Dr. Verena Wally
Manuscript Submission Information
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- squamous cell carcinoma
- tumor profiling
- gene expression