Special Issue "Targeting the Tumor Microenvironment Volume II"

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".

Deadline for manuscript submissions: 31 December 2023 | Viewed by 253

Special Issue Editors

School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK
Interests: signaling; cancer; breast cancer; glioblastoma; microenvironment; exosomes; kinases
Special Issues, Collections and Topics in MDPI journals
Department of Medicine, University of Udine, 33100 Udine, Italy
Interests: protein kinase c; tumor; tgf-beta; pituitary adenoma cells; adrenocortical tumors; medullary thyroid carcinoma cells; tumor microenvironment; medullary thyroid carcinoma; fibroblast
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This collection is the second edition of the Special Issue “Targeting the Tumor Microenvironment” (https://www.mdpi.com/journal/cancers/special_issues/TME).

The tumor microenvironment (TME) plays a pivotal role in different types of cancer. The interactions that occur within the TME are fundamental in tumor-induced suppression of the immune system and metastatic dissemination of cancer cells, and these mechanisms may ultimately affect tumor progression and treatment outcomes. Recently introduced cancer therapies target the interaction between tumors and the TME. However, stromal components of the tumor niche may extensively affect drug response in tumor cells. Furthermore, stroma-targeted strategies have emerged as a new treatment option for many types of cancer. Despite the recent advances in cancer treatment, a proportion of patients remain resistant. Thus, it is necessary to develop innovative therapeutic approaches by investigating the fundamental role of TME. We invite authors to contribute cutting-edge studies to this Special Issue, entitled “Targeting the Tumor Microenvironment”, to further highlight the involvement of TME in cancer progression and treatment.

Prof. Dr. Georgios Giamas
Prof. Dr. Teresa Gagliano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • microenvironment
  • cancer treatment
  • resistance to treatment
  • metastasis
  • immune response
  • immune cells
  • fibroblasts
  • angiogenesis
  • EVs
  • signalling

Published Papers

This special issue is now open for submission.
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