Effect of Altered Sensory and Cognitive Processing on Sensorimotor Integration

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Sensory and Motor Neuroscience".

Deadline for manuscript submissions: closed (10 August 2023) | Viewed by 19015

Special Issue Editor

Faculty of Health Sciences, Ontario Tech University, 2000 Simcoe Street North, Oshawa, ON L1H 7K4, Canada
Interests: sensorimotor integration; neural adaptation and learning; neurophysiology of musculoskeletal treatments; chronic pain processing; neural effects of exercise
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Sensorimotor integration (SMI) refers to the ability to process sensory information and formulate effective motor outputs. Disordered SMI may result from both acute and chronic changes in sensory input. This Special Issue explores the effect of both acute and chronic changes in sensory inputs and how this affects SMI. In addition, it will explore sensorimotor conflicts and how cognitive factors influence the interaction between pain and the motor system, as well as how both acute and chronic effects of altered neck and trunk inputs impact limb sensorimotor control.

Prof. Dr. Bernadette Murphy
Guest Editor

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Keywords

  • sensorimotor integration
  • motor
  • sensory
  • cognition

Published Papers (15 papers)

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Research

14 pages, 2436 KiB  
Article
Investigating Cerebellar Modulation of Premovement Beta-Band Activity during Motor Adaptation
by Lynea B. Kaethler, Katlyn E. Brown, Sean K. Meehan and W. Richard Staines
Brain Sci. 2023, 13(11), 1523; https://doi.org/10.3390/brainsci13111523 - 28 Oct 2023
Viewed by 872
Abstract
Enhancing cerebellar activity influences motor cortical activity and contributes to motor adaptation, though it is unclear which neurophysiological mechanisms contributing to adaptation are influenced by the cerebellum. Pre-movement beta event-related desynchronization (β-ERD), which reflects a release of inhibitory control in the premotor cortex [...] Read more.
Enhancing cerebellar activity influences motor cortical activity and contributes to motor adaptation, though it is unclear which neurophysiological mechanisms contributing to adaptation are influenced by the cerebellum. Pre-movement beta event-related desynchronization (β-ERD), which reflects a release of inhibitory control in the premotor cortex during movement planning, is one mechanism that may be modulated by the cerebellum through cerebellar-premotor connections. We hypothesized that enhancing cerebellar activity with intermittent theta burst stimulation (iTBS) would improve adaptation rates and increase β-ERD during motor adaptation. Thirty-four participants were randomly assigned to an active (A-iTBS) or sham cerebellar iTBS (S-iTBS) group. Participants performed a visuomotor task, using a joystick to move a cursor to targets, prior to receiving A-iTBS or S-iTBS, following which they completed training with a 45° rotation to the cursor movement. Behavioural adaptation was assessed using the angular error of the cursor path relative to the ideal trajectory. The results showed a greater adaptation rate following A-iTBS and an increase in β-ERD, specific to the high β range (20–30 Hz) during motor planning, compared to S-iTBS, indicative of cerebellar modulation of the motor cortical inhibitory control network. The enhanced release of inhibitory activity persisted throughout training, which suggests that the cerebellar influence over the premotor cortex extends beyond adaptation to other stages of motor learning. The results from this study further understanding of cerebellum-motor connections as they relate to acquiring motor skills and may inform future skill training and rehabilitation protocols. Full article
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18 pages, 2759 KiB  
Article
Neck Muscle Vibration Alters Cerebellar Processing Associated with Motor Skill Acquisition of a Proprioceptive-Based Task
by Hailey Tabbert, Ushani Ambalavanar and Bernadette Murphy
Brain Sci. 2023, 13(10), 1412; https://doi.org/10.3390/brainsci13101412 - 04 Oct 2023
Cited by 1 | Viewed by 951
Abstract
Experimentally induced neck fatigue and neck pain have been shown to impact cortico-cerebellar processing and sensorimotor integration, assessed using a motor learning paradigm. Vibration specifically impacts muscle spindle feedback, yet it is unknown whether transient alterations in neck sensory input from vibration impact [...] Read more.
Experimentally induced neck fatigue and neck pain have been shown to impact cortico-cerebellar processing and sensorimotor integration, assessed using a motor learning paradigm. Vibration specifically impacts muscle spindle feedback, yet it is unknown whether transient alterations in neck sensory input from vibration impact these neural processing changes following the acquisition of a proprioceptive-based task. Twenty-five right-handed participants had electrical stimulation over the right median nerve to elicit short- and middle-latency somatosensory evoked potentials (SEPs) pre- and post-acquisition of a force matching tracking task. Following the pre-acquisition phase, controls (CONT, n = 13, 6 F) received 10 min of rest and the vibration group (VIB, n = 12, 6 F) received 10 min of 60 Hz vibration on the right sternocleidomastoid and left cervical extensors. Task performance was measured 24 h later to assess retention. Significant time by group interactions occurred for the N18 SEP peak, 21.77% decrease in VIB compared to 58.74% increase in CONT (F(1,23) = 6.475, p = 0.018, np2 = 0.220), and the N24 SEP peak, 16.31% increase in VIB compared to 14.05% decrease in CONT (F(1,23) = 5.787, p = 0.025, np2 = 0.201). Both groups demonstrated improvements in motor performance post-acquisition (F(1,23) = 52.812, p < 0.001, np2 = 0.697) and at retention (F(1,23) = 35.546, p < 0.001, np2 = 0.607). Group-dependent changes in the SEP peaks associated with cerebellar input (N18) and cerebellar processing (N24) suggests that an altered proprioceptive input from neck vibration impacts cerebellar pathways. Full article
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17 pages, 1693 KiB  
Article
Using Neck Muscle Afferentation to Control an Ongoing Limb Movement? Individual Differences in the Influence of Brief Neck Vibration
by Maria Alekhina, Goran Perkic, Gerome Aleandro Manson, Jean Blouin and Luc Tremblay
Brain Sci. 2023, 13(10), 1407; https://doi.org/10.3390/brainsci13101407 - 01 Oct 2023
Viewed by 737
Abstract
When preparing and executing goal-directed actions, neck proprioceptive information is critical to determining the relative positions of the body and target in space. While the contribution of neck proprioception for upper-limb movements has been previously investigated, we could not find evidence discerning its [...] Read more.
When preparing and executing goal-directed actions, neck proprioceptive information is critical to determining the relative positions of the body and target in space. While the contribution of neck proprioception for upper-limb movements has been previously investigated, we could not find evidence discerning its impact on the planning vs. online control of upper-limb trajectories. To investigate these distinct sensorimotor processes, participants performed discrete reaches towards a virtual target. On some trials, neck vibration was randomly applied before and/or during the movement, or not at all. The main dependent variable was the medio-lateral/directional bias of the reaching finger. The neck vibration conditions induced early leftward trajectory biases in some participants and late rightward trajectory biases in others. These different patterns of trajectory biases were explained by individual differences in the use of body-centered and head-centered frames of reference. Importantly, the current study provides direct evidence that sensory cues from the neck muscles contribute to the online control of goal-directed arm movements, likely accompanied by significant individual differences. Full article
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17 pages, 2311 KiB  
Article
Adapting to Altered Sensory Input: Effects of Induced Paresthesia on Goal-Directed Movement Planning and Execution
by Niyousha Mortaza, Steven R. Passmore and Cheryl M. Glazebrook
Brain Sci. 2023, 13(9), 1341; https://doi.org/10.3390/brainsci13091341 - 19 Sep 2023
Viewed by 766
Abstract
The current study investigated how temporarily induced paresthesia in the moving limb affects the performance of a goal-directed target aiming task. Three-dimensional displacement data of 14 neurotypical participants were recorded while they pointed to a target on a computer monitor in four conditions: [...] Read more.
The current study investigated how temporarily induced paresthesia in the moving limb affects the performance of a goal-directed target aiming task. Three-dimensional displacement data of 14 neurotypical participants were recorded while they pointed to a target on a computer monitor in four conditions: (i) paresthesia-full-vision; (ii) paresthesia-without-target vision; (iii) no-paresthesia-full-vision; (iv) no paresthesia-without-target vision. The four conditions were blocked and counterbalanced such that participants performed the paresthesia and no-paresthesia conditions on two separate days. To assess how aiming performance changed in the presence of paresthesia, we compared early versus late performance (first and last 20% of trials). We found that endpoint accuracy and movement speed were reduced in the presence of paresthesia, but only without target vision. With repetition, participants adjusted their movement performance strategy, such that with induced paresthesia, they used a movement strategy that included more pre-planned movements that depended less on online control. Full article
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24 pages, 2259 KiB  
Article
Optimizing Movement Performance with Altered Sensation: An Examination of Multisensory Inputs
by Niyousha Mortaza, Steven R. Passmore and Cheryl M. Glazebrook
Brain Sci. 2023, 13(9), 1302; https://doi.org/10.3390/brainsci13091302 - 09 Sep 2023
Viewed by 651
Abstract
Two experiments were conducted to assess the impact of induced paresthesia on movement parameters of goal-directed aiming movements to determine how visual and auditory feedback may enhance performance when somatosensory feedback is disrupted. In both experiments, neurotypical adults performed the goal-directed aiming task [...] Read more.
Two experiments were conducted to assess the impact of induced paresthesia on movement parameters of goal-directed aiming movements to determine how visual and auditory feedback may enhance performance when somatosensory feedback is disrupted. In both experiments, neurotypical adults performed the goal-directed aiming task in four conditions: (i) paresthesia—full vision; (ii) paresthesia—no vision; (iii) no paresthesia—full vision; (iv) no paresthesia—no vision. Targets appeared on a computer screen, vision was obscured using visual occlusion spectacles, and paresthesia was induced with a constant current stimulator. The first and last 20% of trials (early and late performance) were compared to assess adaptability to altered somatosensory input. Experiment 2 added an auditory tone that confirmed successful target acquisitions. When compared to early performance in the no-paresthesia and no-vision conditions, induced paresthesia and no vision led to significantly larger endpoint error toward the body midline in both early and late performance. This finding reveals the importance of proprioceptive input for movement accuracy in the absence of visual feedback. The kinematic results indicated that vision could not fully compensate for the disrupted proprioceptive input when participants experienced induced paresthesia. However, when auditory feedback confirmed successful aiming movements in Experiment 2, participants were able to improve their endpoint variability when experiencing induced paresthesia through changes in movement preparation. Full article
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15 pages, 2613 KiB  
Article
The Impact of Limited Previous Motor Experience on Action Possibility Judgments in People with Spinal Muscle Atrophy
by Sarvenaz Heirani Moghaddam, Dilara Sen, Megan Carson, Robert Mackowiak, Rachel Markley and Gerome Aleandro Manson
Brain Sci. 2023, 13(9), 1256; https://doi.org/10.3390/brainsci13091256 - 29 Aug 2023
Viewed by 782
Abstract
Previous studies have shown that people with limited motor capabilities may rely on previous motor experience when making action possibility judgments for others. In the present study, we examined if having limited previous motor experience, as a consequence of spinal muscle atrophy (SMA), [...] Read more.
Previous studies have shown that people with limited motor capabilities may rely on previous motor experience when making action possibility judgments for others. In the present study, we examined if having limited previous motor experience, as a consequence of spinal muscle atrophy (SMA), alters action possibility judgments. Participants with SMA and neurologically healthy (NH) sex- and age-matched controls performed a perceptual-motor judgment task using the Fitts’s law paradigm. Participants observed apparent motion videos of reciprocal aiming movements with varying levels of difficulty. For each movement, participants predicted the shortest movement time (MT) at which a neurologically healthy young adult could accurately perform the task. Participants with SMA predicted significantly longer MTs compared to controls; however, the predicted MTs of both SMA and NH participants exhibited a Fitts’s law relationship (i.e., the predicted MTs significantly increased as movement difficulty increased). Overall, these results provide evidence that participants with SMA who have limited, or no motor experience may make more conservative action possibility judgments for others. Critically, our finding that the pattern of action possibility judgments was not different between SMA and NH groups suggests that limited previous motor experience may not completely impair action possibility judgments. Full article
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11 pages, 488 KiB  
Article
Explanatory Capacity of Postural Control and Physical Fitness in Cognitive Impairment and Support Needs among Individuals with Intellectual Disabilities—A Cross-Sectional Pilot Study
by María Mercedes Reguera-García, Eva Fernández-Baró, Ignacio Diez-Vega, Irene Varona-Echave and Jesús Seco-Calvo
Brain Sci. 2023, 13(8), 1213; https://doi.org/10.3390/brainsci13081213 - 17 Aug 2023
Viewed by 918
Abstract
Postural control is a skill associated with most motor activities and is essential for the performance of activities of daily living. People with intellectual disabilities (ID) present postural control deficits that can be attributed to several causes. The aim of this study was [...] Read more.
Postural control is a skill associated with most motor activities and is essential for the performance of activities of daily living. People with intellectual disabilities (ID) present postural control deficits that can be attributed to several causes. The aim of this study was to determine whether postural control and physical fitness could explain the cognitive impairment and support needs in this population. A cross-sectional pilot study was conducted with 18 people with ID. Data collection was based on assessments for postural control (Mini BESTest and Berg Balance Scale) and physical fitness (Senior Fitness Test). The data were analyzed using linear regression models. Anticipatory postural adjustments were associated with support needs, explaining up to 45% of these. Consecutive postural adjustments and upper limb strength were less significantly associated with support needs. However, none of the variables used explained cognitive impairment in ID. Knowledge of the relationships and behavior of the different measurement tools is essential for the development of appropriate interventions in this population. Full article
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13 pages, 923 KiB  
Article
Relationship between Motor Corticospinal System, Endogenous Pain Modulation Mechanisms and Clinical Symptoms in Patients with Knee Osteoarthritis: New Perspectives on an Old Disease
by Marylie Martel, Nathaly Gaudreault, René Pelletier, Francis Houde, Marie-Philippe Harvey, Caroline Giguère, Frédéric Balg and Guillaume Leonard
Brain Sci. 2023, 13(8), 1154; https://doi.org/10.3390/brainsci13081154 - 01 Aug 2023
Viewed by 846
Abstract
Knee osteoarthritis (OA) is a painful condition characterized by joint and bone changes. A growing number of studies suggest that these changes only partially explain the pain experienced by individuals with OA. The purpose of the current study was to evaluate if corticospinal [...] Read more.
Knee osteoarthritis (OA) is a painful condition characterized by joint and bone changes. A growing number of studies suggest that these changes only partially explain the pain experienced by individuals with OA. The purpose of the current study was to evaluate if corticospinal and bulbospinal projection measurements were interrelated in patients with knee OA, and to explore the relationship between these neurophysiological measures and temporal summation (excitatory mechanisms of pain) on one hand, and clinical symptoms on the other. Twenty-eight (28) patients with knee OA were recruited. Corticospinal projections were measured using transcranial magnetic stimulation, while bulbospinal projections were evaluated with a conditioned pain modulation (CPM) protocol using a counter-irritation paradigm. Validated questionnaires were used to document clinical and psychological manifestations. All participants suffered from moderate to severe pain. There was a positive association between corticospinal excitability and the effectiveness of the CPM (rs = 0.67, p = 0.01, n = 13). There was also a positive relationship between pain intensity and corticospinal excitability (rs = 0.45, p = 0.03, n = 23), and between pain intensity and temporal summation (rs = 0.58, p = 0.01, n = 18). The results of this study highlight some of the central nervous system changes that could be involved in knee OA and underline the importance of interindividual variability to better understand and explain the semiology and pathophysiology of knee OA. Full article
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9 pages, 610 KiB  
Article
Could Vulnerability to Motion Sickness and Chronic Pain Coexist within a Sensorimotor Phenotype? Insights from over 500 Pre-Pain Motion Sickness Reports
by Daniel Simon Harvie
Brain Sci. 2023, 13(7), 1063; https://doi.org/10.3390/brainsci13071063 - 12 Jul 2023
Cited by 1 | Viewed by 1040
Abstract
Background: The sensorimotor incongruence theory proposes that certain instances of pain result from conflicts in the brain’s sensorimotor networks. Indeed, injuries may cause abnormalities in afferent and cortical signaling resulting in such conflicts. Motion sickness also occurs in instances of incongruent sensorimotor data. [...] Read more.
Background: The sensorimotor incongruence theory proposes that certain instances of pain result from conflicts in the brain’s sensorimotor networks. Indeed, injuries may cause abnormalities in afferent and cortical signaling resulting in such conflicts. Motion sickness also occurs in instances of incongruent sensorimotor data. It is possible that a sensory processing phenotype exists that predisposes people to both conditions. Aim: The aim of this study was to investigate whether participants with chronic pain recall greater susceptibility to motion sickness before chronic pain onset. Method: Data were collected via an online LimeSurvey. A self-report tendency toward motion sickness was measured using the Motion Sickness Susceptibility Questionnaire. Group differences were analysed using analysis of covariance methods. Results: 530 patients (low back pain, n = 198; neck pain, n = 59; whiplash-associated disorder, n = 72; fibromyalgia syndrome, n = 114; Migraine, n = 41) and 165 pain-free controls were surveyed. ANCOVA analysis, using sex and anxiety as covariates, suggested that childhood motion sickness susceptibility scores differed by group (F = 2.55 (6, 615), p = 0.019, (ηp2) = 0.024). Planned comparisons, with corrected p-values, suggested that childhood motion sickness was not statistically greater for low back pain, rheumatoid arthritis, migraine, neck pain or whiplash-associated disorder (ps > 0.05), although scores were on average 27%, 42%, 47%, 48% and 58% higher, respectively. Childhood susceptibility was statistically higher in people with FMS (p = 0.018), with scores on average 83% higher than controls. ANCOVA analysis, using sex and anxiety as covariates, suggested that adult motion sickness susceptibility scores did not differ by group (F = 1.86 (6, 613), p = 0.086), although average scores were, on average, at least 33% higher in persistent pain groups. Conclusions: According to retrospective reporting, greater susceptibility to motion sickness appears to pre-date persistent pain in some conditions. This supports the possibility that motion sickness and chronic pain may, in some cases, have overlapping mechanisms related to the handling of incongruent sensorimotor data. Full article
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31 pages, 727 KiB  
Article
Non-Specific Low Back Pain: An Inductive Exploratory Analysis through Factor Analysis and Deep Learning for Better Clustering
by Lucien Robinault, Imran Khan Niazi, Nitika Kumari, Imran Amjad, Vincent Menard and Heidi Haavik
Brain Sci. 2023, 13(6), 946; https://doi.org/10.3390/brainsci13060946 - 13 Jun 2023
Viewed by 2074
Abstract
Non-specific low back pain (NSLBP) is a significant and pervasive public health issue in contemporary society. Despite the widespread prevalence of NSLBP, our understanding of its underlying causes, as well as our capacity to provide effective treatments, remains limited due to the high [...] Read more.
Non-specific low back pain (NSLBP) is a significant and pervasive public health issue in contemporary society. Despite the widespread prevalence of NSLBP, our understanding of its underlying causes, as well as our capacity to provide effective treatments, remains limited due to the high diversity in the population that does not respond to generic treatments. Clustering the NSLBP population based on shared characteristics offers a potential solution for developing personalized interventions. However, the complexity of NSLBP and the reliance on subjective categorical data in previous attempts present challenges in achieving reliable and clinically meaningful clusters. This study aims to explore the influence and importance of objective, continuous variables related to NSLBP and how to use these variables effectively to facilitate the clustering of NSLBP patients into meaningful subgroups. Data were acquired from 46 subjects who performed six simple movement tasks (back extension, back flexion, lateral trunk flexion right, lateral trunk flexion left, trunk rotation right, and trunk rotation left) at two different speeds (maximum and preferred). High-density electromyography (HD EMG) data from the lower back region were acquired, jointly with motion capture data, using passive reflective markers on the subject’s body and clusters of markers on the subject’s spine. An exploratory analysis was conducted using a deep neural network and factor analysis. Based on selected variables, various models were trained to classify individuals as healthy or having NSLBP in order to assess the importance of different variables. The models were trained using different subsets of data, including all variables, only anthropometric data (e.g., age, BMI, height, weight, and sex), only biomechanical data (e.g., shoulder and lower back movement), only neuromuscular data (e.g., HD EMG activity), or only balance-related data. The models achieved high accuracy in categorizing individuals as healthy or having NSLBP (full model: 93.30%, anthropometric model: 94.40%, biomechanical model: 84.47%, neuromuscular model: 88.07%, and balance model: 74.73%). Factor analysis revealed that individuals with NSLBP exhibited different movement patterns to healthy individuals, characterized by slower and more rigid movements. Anthropometric variables (age, sex, and BMI) were significantly correlated with NSLBP components. In conclusion, different data types, such as body measurements, movement patterns, and neuromuscular activity, can provide valuable information for identifying individuals with NSLBP. To gain a comprehensive understanding of NSLBP, it is crucial to investigate the main domains influencing its prognosis as a cohesive unit rather than studying them in isolation. Simplifying the conditions for acquiring dynamic data is recommended to reduce data complexity, and using back flexion and trunk rotation as effective options should be further explored. Full article
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22 pages, 2235 KiB  
Article
Behavioral and Electrocortical Response to a Sensorimotor Conflict in Individuals with Fibromyalgia
by Tania Augière, Martin Simoneau, Clémentine Brun, Anne Marie Pinard, Jean Blouin, Laurence Mouchnino and Catherine Mercier
Brain Sci. 2023, 13(6), 931; https://doi.org/10.3390/brainsci13060931 - 08 Jun 2023
Viewed by 978
Abstract
People with fibromyalgia have been shown to experience more somatosensory disturbances than pain-free controls during sensorimotor conflicts (i.e., incongruence between visual and somatosensory feedback). Sensorimotor conflicts are known to disturb the integration of sensory information. This study aimed to assess the cerebral response [...] Read more.
People with fibromyalgia have been shown to experience more somatosensory disturbances than pain-free controls during sensorimotor conflicts (i.e., incongruence between visual and somatosensory feedback). Sensorimotor conflicts are known to disturb the integration of sensory information. This study aimed to assess the cerebral response and motor performance during a sensorimotor conflict in people with fibromyalgia. Twenty participants with fibromyalgia and twenty-three pain-free controls performed a drawing task including visual feedback that was either congruent with actual movement (and thus with somatosensory information) or incongruent with actual movement (i.e., conflict). Motor performance was measured according to tracing error, and electrocortical activity was recorded using electroencephalography. Motor performance was degraded during conflict for all participants but did not differ between groups. Time–frequency analysis showed that the conflict was associated with an increase in theta power (4–8 Hz) at conflict onset over the left posterior parietal cortex in participants with fibromyalgia but not in controls. This increase in theta suggests a stronger detection of conflict in participants with fibromyalgia, which was not accompanied by differences in motor performance in comparison to controls. This points to dissociation in individuals with fibromyalgia between an altered perception of action and a seemingly unaltered control of action. Full article
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15 pages, 1429 KiB  
Article
Reversed Mirror Therapy (REMIT) after Stroke—A Proof-of-Concept Study
by Luigi Tesio, Antonio Caronni, Cristina Russo, Giorgio Felisari, Elisabetta Banco, Anna Simone, Stefano Scarano and Nadia Bolognini
Brain Sci. 2023, 13(6), 847; https://doi.org/10.3390/brainsci13060847 - 24 May 2023
Viewed by 1569
Abstract
In mirror training (MIT), stroke patients strive to move their hands while looking at the reflected image of the unaffected one. The recruitment of the mirror neurons and visual-proprioceptive conflict are expected to facilitate the paretic voluntary movement. Here, a reversed MIT (REMIT) [...] Read more.
In mirror training (MIT), stroke patients strive to move their hands while looking at the reflected image of the unaffected one. The recruitment of the mirror neurons and visual-proprioceptive conflict are expected to facilitate the paretic voluntary movement. Here, a reversed MIT (REMIT) is presented, which requires moving hands while looking at the reflected image of the paretic one, giving the illusion of being unable to move the unimpaired hand. This study compares MIT and REMIT on post-stroke upper-limb recovery to gain clues on the mechanism of action of mirror therapies. Eight chronic stroke patients underwent two weeks of MIT and REMIT (five sessions each) in a crossover design. Upper-limb Fugl-Meyer, Box and Block and handgrip strength tests were administered at baseline and treatments end. The strength of the mirror illusion was evaluated after each session. MIT induced a larger illusory effect. The Fugl-Meyer score improved to the same extent after both treatments. No changes occurred in the Box and Block and the handgrip tests. REMIT and MIT were equally effective on upper-limb dexterity, challenging the exclusive role of mirror neurons. Contrasting learned nonuse through an intersensory conflict might provide the rationale for both forms of mirror-based rehabilitation after stroke. Full article
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29 pages, 3803 KiB  
Article
Improved Spatial Knowledge Acquisition through Sensory Augmentation
by Vincent Schmidt, Sabine U. König, Rabia Dilawar, Tracy Sánchez Pacheco and Peter König
Brain Sci. 2023, 13(5), 720; https://doi.org/10.3390/brainsci13050720 - 25 Apr 2023
Cited by 1 | Viewed by 2853
Abstract
Sensory augmentation provides novel opportunities to broaden our knowledge of human perception through external sensors that record and transmit information beyond natural perception. To assess whether such augmented senses affect the acquisition of spatial knowledge during navigation, we trained a group of 27 [...] Read more.
Sensory augmentation provides novel opportunities to broaden our knowledge of human perception through external sensors that record and transmit information beyond natural perception. To assess whether such augmented senses affect the acquisition of spatial knowledge during navigation, we trained a group of 27 participants for six weeks with an augmented sense for cardinal directions called the feelSpace belt. Then, we recruited a control group that did not receive the augmented sense and the corresponding training. All 53 participants first explored the Westbrook virtual reality environment for two and a half hours spread over five sessions before assessing their spatial knowledge in four immersive virtual reality tasks measuring cardinal, route, and survey knowledge. We found that the belt group acquired significantly more accurate cardinal and survey knowledge, which was measured in pointing accuracy, distance, and rotation estimates. Interestingly, the augmented sense also positively affected route knowledge, although to a lesser degree. Finally, the belt group reported a significant increase in the use of spatial strategies after training, while the groups’ ratings were comparable at baseline. The results suggest that six weeks of training with the feelSpace belt led to improved survey and route knowledge acquisition. Moreover, the findings of our study could inform the development of assistive technologies for individuals with visual or navigational impairments, which may lead to enhanced navigation skills and quality of life. Full article
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19 pages, 7018 KiB  
Article
Source Localization of Somatosensory Neural Generators in Adults with Attention-Deficit/Hyperactivity Disorder
by Heather S. McCracken, Bernadette A. Murphy, Ushani Ambalavanar, Cheryl M. Glazebrook and Paul C. Yielder
Brain Sci. 2023, 13(2), 370; https://doi.org/10.3390/brainsci13020370 - 20 Feb 2023
Cited by 1 | Viewed by 1644
Abstract
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, where differences are often present relating to the performance of motor skills. Our previous work elucidated unique event-related potential patterns of neural activity in those with ADHD when performing visuomotor and force-matching motor paradigms. The purpose [...] Read more.
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, where differences are often present relating to the performance of motor skills. Our previous work elucidated unique event-related potential patterns of neural activity in those with ADHD when performing visuomotor and force-matching motor paradigms. The purpose of the current study was to identify whether there were unique neural sources related to somatosensory function and motor performance in those with ADHD. Source localization (sLORETA) software identified areas where neural activity differed between those with ADHD and neurotypical controls when performing a visuomotor tracing task and force-matching task. Median nerve somatosensory evoked potentials (SEPs) were elicited, while whole-head electroencephalography (EEG) was performed. sLORETA localized greater neural activity post-FMT in those with ADHD, when compared with their baseline activity (p < 0.05). Specifically, greater activity was exhibited in BA 31, precuneus, parietal lobe (MNI coordinates: X = −5, Y = −75, and Z = 20) at 156 ms post stimulation. No significant differences were found for any other comparisons. Increased activity within BA 31 in those with ADHD at post-FMT measures may reflect increased activation within the default mode network (DMN) or attentional changes, suggesting a unique neural response to the sensory processing of force and proprioceptive afferent input in those with ADHD when performing motor skills. This may have important functional implications for motor tasks dependent on similar proprioceptive afferent input. Full article
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14 pages, 1666 KiB  
Article
Neck Muscle Vibration Alters Upper Limb Proprioception as Demonstrated by Changes in Accuracy and Precision during an Elbow Repositioning Task
by Hailey Tabbert, Ushani Ambalavanar and Bernadette Murphy
Brain Sci. 2022, 12(11), 1532; https://doi.org/10.3390/brainsci12111532 - 12 Nov 2022
Cited by 3 | Viewed by 1208
Abstract
Upper limb control depends on accurate internal models of limb position relative to the head and neck, accurate sensory inputs, and accurate cortical processing. Transient alterations in neck afferent feedback induced by muscle vibration may impact upper limb proprioception. This research aimed to [...] Read more.
Upper limb control depends on accurate internal models of limb position relative to the head and neck, accurate sensory inputs, and accurate cortical processing. Transient alterations in neck afferent feedback induced by muscle vibration may impact upper limb proprioception. This research aimed to determine the effects of neck muscle vibration on upper limb proprioception using a novel elbow repositioning task (ERT). 26 right-handed participants aged 22.21 ± 2.64 performed the ERT consisting of three target angles between 80–90° (T1), 90–100° (T2) and 100–110° (T3). Controls (CONT) (n = 13, 6F) received 10 min of rest and the vibration group (VIB) (n = 13, 6F) received 10 min of 60 Hz vibration over the right sternocleidomastoid and left cervical extensor muscles. Task performance was reassessed following experimental manipulation. Significant time by group interactions occurred for T1: (F1,24 = 25.330, p < 0.001, ηp2 = 0.513) where CONT improved by 26.08% and VIB worsened by 134.27%, T2: (F1,24 = 16.157, p < 0.001, ηp2 = 0.402) where CONT improved by 20.39% and VIB worsened by 109.54%, and T3: (F1,24 = 21.923, p < 0.001, ηp2 = 0.447) where CONT improved by 37.11% and VIB worsened by 54.39%. Improvements in repositioning accuracy indicates improved proprioceptive ability with practice in controls. Decreased accuracy following vibration suggests that vibration altered proprioceptive inputs used to construct body schema, leading to inaccurate joint position sense and the observed changes in elbow repositioning accuracy. Full article
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