Multiple Sclerosis and Related Disorders: From Diagnosis to Treatment

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 1005

Special Issue Editor

Centro de Esclerosis Múltiple de Buenos Aires, Buenos Aires, Argentina
Interests: MS

Special Issue Information

Dear Colleagues,

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS), with an onset between 20 and 40 years and a higher prevalence in women. Diagnosis of MS is based on the integration of clinical, imaging and laboratory findings, and the exclusion of alternative disorders remains crucial. As the armamentarium of disease-modifying treatments (DMT) has broadened, robust diagnosis in the early phase of the disease has become increasingly critical.

Studies published in this Special Issue of Brain Science will focus on the diagnosis and treatment of MS and neuromyelitis optica spectrum disorders (NMOSD). Authors are invited to submit cutting-edge research and reviews related to MS and NMOSD including the following topics: epidemiology, diagnosis, differential diagnosis, new advances in MRI, body fluid biomarkers, treatment algorithms, Patients Reported Outcomes (PRO) and quality of life.

Submissions should be based on Real-World Data (RWD) and Real-World Evidence (RWE) and its impact and relevance in daily clinical practice.

Dr. Liliana Patrucco
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • multiple sclerosis
  • NMOSD
  • diagnosis

Published Papers (1 paper)

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Review

12 pages, 278 KiB  
Review
Impact of Disease Modifying Therapy on MS-Related Fatigue: A Narrative Review
by Mahmoud Elkhooly, Fen Bao and Evanthia Bernitsas
Brain Sci. 2024, 14(1), 4; https://doi.org/10.3390/brainsci14010004 - 20 Dec 2023
Viewed by 788
Abstract
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system by causing inflammation, demyelination and neurodegeneration. Fatigue is the most prevalent and one of the most disabling symptoms among people with MS (pwMS). Due to its complexity and subjective [...] Read more.
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system by causing inflammation, demyelination and neurodegeneration. Fatigue is the most prevalent and one of the most disabling symptoms among people with MS (pwMS). Due to its complexity and subjective character, fatigue is still little understood despite its frequent occurrence and severe impact. The potential causes, effects, and treatments of fatigue associated with MS have been extensively studied in recent years. Though the benefits of such a variety of contributions are obvious, there have not been many attempts to evaluate the effect of disease modifying therapies (DMTs) on MS-related fatigue. In this review, we summarize clinical trials and research studies, and we discuss the effect of different DMTs on MS-related fatigue. Full article
(This article belongs to the Special Issue Multiple Sclerosis and Related Disorders: From Diagnosis to Treatment)
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