Vascular Contributions to Cognitive Impairments
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: closed (1 November 2023) | Viewed by 221
Special Issue Editor
Interests: surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease and related dementias remain the leading cause of death and disability worldwide. However, the current beta-amyloid (Aβ) and tau-targeting therapies for Alzheimer’s disease failed in the clinical trials, and whether Aβ accumulation is the cause or consequence of Alzheimer’s disease is unclear.
Vascular contributions to cognitive impairments have been fascinating, and the immunological mechanisms underlying cognitive impairments remain to be determined. The interaction of cerebrovascular cells and immune cells in Alzheimer’s disease is largely unknown. The role of risk factors including aging, cardiovascular diseases, and chronic inflammation are also attracting attention by researchers to investigate the novel mechanisms underlying the pathogenesis of Alzheimer’s disease and related dementias. The present Special Issue aims to include research in all the areas related to studies in Alzheimer’s disease and related dementias, cerebrovascular dysfunction, and cerebrovascular-immune cell interaction. We invite manuscripts in the form of original research, reviews, mini-reviews, and short communications investigating/commenting on the novel mechanisms of the pathogenesis of Alzheimer’s disease and related dementias.
Potential topics include, but are not limited to:
- Beta-amyloid (Aβ) and tau pathology
- Interaction of cerebrovascular cells with the immune system
- Risk factors: Lifestyle, cardiovascular diseases, and chronic inflammation et al. in the contribution to Alzheimer's dementia and related dementias
- Cerebrovascular dysfunction, blood-brain barrier leakage, cerebral blood flow dysregulation, neurovascular coupling, cerebrovascular remodeling et al. in Alzheimer's and related dementias
- Novel therapies for the treatment of Alzheimer's disease and related dementias.
Dr. Shaoxun Wang
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immune cells
- cerebrovascular dysfunction
- Alzheimer’s diseases
- risk factors
