Special Issue "Current Advance in Transistor-Based Biosensors for Diagnostics"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (1 April 2023) | Viewed by 1486

Special Issue Editors

Laboratory of Organic Electronics (LEO), Department of Life Science, University of Modena and Reggio Emilia, via Campi 213/a, 41125 Modena, Italy
Interests: biosensors; egofet; oect; electrochemistry; impedance; organic electronics; rGO
Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy
Interests: biophysical chemistry; organic bioelectronics; electron transfer
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Special Issue Information

Dear Colleagues,

Transistor-based biosensors have exhibited outstanding performances in the last decade in terms of selectivity, limit of detection, and portability. Thanks to the properties of active materials, transistor-based biosensors can be realized on flexible substrates with cost-effective printing techniques, characteristics that make these devices suitable to realize diagnostic platforms at the point of care.

This Special Issue aims to collect papers on the latest advances in the field of biosensing for diagnostics, underlining proof-of-concept innovations in terms of technology, targets, and portability. Applications to achieve biosensing with samples from patients and technological solutions for point-of-care applications are welcome.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: field-effect transistor (FET) biosensors for diagnostics based on organic semiconductors, carbon nanotubes, graphene, and inorganic semiconductors; microfluidics platforms for FETs; and new device architectures for point-of-care applications.

We look forward to receiving your contributions.

Dr. Matteo Sensi
Dr. Carlo Augusto Bortolotti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • transistors
  • biosensors
  • diagnostics
  • FET
  • GFET
  • OECT
  • EGOFET
  • point-of-care

Published Papers (1 paper)

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Research

Communication
A Fast and Label-Free Potentiometric Method for Direct Detection of Glutamine with Silicon Nanowire Biosensors
Biosensors 2022, 12(6), 368; https://doi.org/10.3390/bios12060368 - 27 May 2022
Cited by 1 | Viewed by 1176
Abstract
In this paper, a potentiometric method is used for monitoring the concentration of glutamine in the bioprocess by employing silicon nanowire biosensors. Just one hydrolyzation reaction was used, which is much more convenient compared with the two-stage reactions in the published papers. For [...] Read more.
In this paper, a potentiometric method is used for monitoring the concentration of glutamine in the bioprocess by employing silicon nanowire biosensors. Just one hydrolyzation reaction was used, which is much more convenient compared with the two-stage reactions in the published papers. For the silicon nanowire biosensor, the Al2O3 sensing layer provides a highly sensitive to solution-pH, which has near-Nernstian sensitivity. The sensitive region to detect glutamine is from ≤40 μM to 20 mM. The Sigmoidal function was used to model the pH-signal variation versus the glutamine concentration. Compared with the amperometric methods, a consistent result from different devices could be directly obtained. It is a fast and direct method achieved with our real-time setup. Also, it is a label-free method because just the pH variation of the solution is monitored. The obtained results show the feasibility of the potentiometric method for monitoring the glutamine concentrations in fermentation processes. Our approach in this paper can be applied to various analytes. Full article
(This article belongs to the Special Issue Current Advance in Transistor-Based Biosensors for Diagnostics)
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