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Biosensors
Special Issues
Nanoparticle-Based Biosensors and Their Applications
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Special Issue "Nanoparticle-Based Biosensors and Their Applications"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: 30 April 2024 | Viewed by 5004

Special Issue Editors

Dr. Yang Zhang

E-Mail Website
Guest Editor
Institute of Photonics Technology, Jinan University, Guangzhou 511443, China
Interests: biosensors; photodetectors; sensors; nanofabrication; nanoelectronics; integrated photonics; semiconductor devices; semiconductor physics
Special Issues, Collections and Topics in MDPI journals
Dr. Yufeng Liu
E-Mail Website
Guest Editor
School of Materials Science and Engineering, Shanghai Institute of Technology, Shanghai 201418, China
Interests: biosensors; quantum dots; optoelectronic divices
Prof. Dr. Fu-Gen Wu

E-Mail Website
Guest Editor
State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, 2 Sipailou Road, Nanjing 210096, China
Interests: biosensors; drug delivery; nanomedicine; cancer therapy; antibacterial; pharmaceuticals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biosensors are indispensable devices for information acquisition and transformation in the era of the Internet of things (IoT). In scientific research, the information conveyed by these sensors can often provide invaluable insights into the nature of many physical, chemical, and biological phenomena. Nanoparticles are a reduced dimensional form of matter that feature large surface-to-volume ratios and inherently entail a set of unique physical and chemical properties, such as a quantum confinement effect, plamonic effect, enhanced catalytic activity, enhanced surface reactivity, etc. Leveraging these properties for sensing may help boost the sensitivity of existing biosensors.

In this Special Issue, “Nanoparticle-Based Biosensors”, we invite the authors to submit original research and comprehensive review papers with experimental and/or theoretical results on leveraging nanoparticles for biosensing. The research topics are broadly defined, including, but not limited to, nanoparticle preparation and characterization, the application of nanoparticles for biosensing, sensor interfacing and signal processing, etc.

Dr. Yang Zhang
Dr. Yufeng Liu
Prof. Dr. Fu-Gen Wu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanoparticles
  • quantum dots
  • photodetectors
  • biosensors
  • nanoprobes
  • imaging
  • fluorescence
  • infrared
  • light emission
  • read-out circuits

Published Papers (2 papers)

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Research

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Article
Sulfur-Doped Organosilica Nanodots as a Universal Sensor for Ultrafast Live/Dead Cell Discrimination
by
Yan-Hong Li
,
Jia Zeng
,
Zihao Wang
,
Tian-Yu Wang
,
Shun-Yu Wu
,
Xiao-Yu Zhu
,
Xinping Zhang
,
Bai-Hui Shan
,
Cheng-Zhe Gao
,
Shi-Hao Wang
and
Fu-Gen Wu
Biosensors 2022, 12(11), 1000; https://doi.org/10.3390/bios12111000 - 10 Nov 2022
Cited by 2 | Viewed by 1427
Abstract
Rapid and accurate differentiation between live and dead cells is highly desirable for the evaluation of cell viability. Here, we report the application of the orange-emitting sulfur-doped organosilica nanodots (S-OSiNDs) for ultrafast (30 s), ultrasensitive (1 μg/mL), and universal staining of the dead [...] Read more.
Rapid and accurate differentiation between live and dead cells is highly desirable for the evaluation of cell viability. Here, we report the application of the orange-emitting sulfur-doped organosilica nanodots (S-OSiNDs) for ultrafast (30 s), ultrasensitive (1 μg/mL), and universal staining of the dead bacterial, fungal, and mammalian cells but not the live ones, which satisfies the requirements of a fluorescent probe that can specifically stain the dead cells. We further verify that the fluorescence distribution range of S-OSiNDs (which are distributed in cytoplasm and nucleus) is much larger than that of the commercial dead/fixed cell/tissue staining dye RedDot2 (which is distributed in the nucleus) in terms of dead mammalian cell staining, indicating that S-OSiNDs possess a better staining effect of dead cells than RedDot2. Overall, S-OSiNDs can be used as a robust fluorescent probe for ultrafast and accurate discrimination between dead and live cells at a single cell level, which may find a variety of applications in the biomedical field. Full article
(This article belongs to the Special Issue Nanoparticle-Based Biosensors and Their Applications)
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Review

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Review
Graphene-Based Electrochemical Biosensors for Breast Cancer Detection
by
Ali Mohammadpour-Haratbar
,
Seyyed Behnam Abdollahi Boraei
,
Yasser Zare
,
Kyong Yop Rhee
and
Soo-Jin Park
Biosensors 2023, 13(1), 80; https://doi.org/10.3390/bios13010080 - 03 Jan 2023
Cited by 8 | Viewed by 2931
Abstract
Breast cancer (BC) is the most common cancer in women, which is also the second most public cancer worldwide. When detected early, BC can be treated more easily and prevented from spreading beyond the breast. In recent years, various BC biosensor strategies have [...] Read more.
Breast cancer (BC) is the most common cancer in women, which is also the second most public cancer worldwide. When detected early, BC can be treated more easily and prevented from spreading beyond the breast. In recent years, various BC biosensor strategies have been studied, including optical, electrical, electrochemical, and mechanical biosensors. In particular, the high sensitivity and short detection time of electrochemical biosensors make them suitable for the recognition of BC biomarkers. Moreover, the sensitivity of the electrochemical biosensor can be increased by incorporating nanomaterials. In this respect, the outstanding mechanical and electrical performances of graphene have led to an increasingly intense study of graphene-based materials for BC electrochemical biosensors. Hence, the present review examines the latest advances in graphene-based electrochemical biosensors for BC biosensing. For each biosensor, the detection limit (LOD), linear range (LR), and diagnosis technique are analyzed. This is followed by a discussion of the prospects and current challenges, along with potential strategies for enhancing the performance of electrochemical biosensors. Full article
(This article belongs to the Special Issue Nanoparticle-Based Biosensors and Their Applications)
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