Special Issue "Electrochemical Aptasensors: From Design to Applications"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 481

Special Issue Editors

Department of Chemistry "Ugo Schiff", University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, FI, Italy
Interests: electrochemical biosensors; optical biosensors; DNA receptors; aptamer assays; food contaminants; conducting polymers; metal nanoparticles; voltammetric techniques
Special Issues, Collections and Topics in MDPI journals
Department of Chemistry “Ugo Schiff”, University of Florence, via della Lastruccia 3, 50019 Sesto Fiorentino, Italy
Interests: immobilization procedure of biomolecules; protein–DNA complexes; aptamer; enzymatic sensors; thick-film technology; nanodispensing technologies; micro-flow systems; carbon nanotubes; nanoparticles; nanocomposite polymers; molecular imprinted polymers; protein-polymer conjugates
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent progress in bioanalytical applications has significantly benefited from the synthesis and characterization of new classes of biomimetic receptors, such as nucleic acid ligands, coupled to electrochemical instrumentation. The combination between aptamers and electrochemistry offers the possibility to develop a huge number of simple-to-use devices with a low cost, fast and sensitive response and high selectivity.

Many different designs were applied in the development of electrochemical aptasensors: a device as such is usually composed of an aptamer, used as the molecular probe, and an electrochemical transducer, used to convert the chemical reaction resulting from the interaction of the target with the bioreceptor into an electronic signal that can be elaborated by a computer. Control of the immobilization process is essential for assuring high reactivity, proper orientation, accessibility and stability of the surface-confined aptamer probe as well as for minimizing non-specific adsorption events. The choice of a proper blocking step and of the most suitable assay format and aptasensing strategy is also peculiar.

This Special Issue aims to share new developments in the design of electrochemical aptasensors, in the form of original research or review articles, including also a focus on their applications. The state of the art should be presented, as well as the addressing of the new challenges that are being faced and the understanding of the perspectives on the future of the field.

I look forward to your contributions.

Dr. Giulia Selvolini
Prof. Dr. Giovanna Marrazza
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • aptasensors
  • aptamers
  • nucleotides
  • electrochemical techniques
  • nanomaterials
  • real-time analysis
  • sensor design
  • sensing mechanism
  • point-of-care diagnostics
  • miniaturized systems
  • specific applications.

Published Papers

There is no accepted submissions to this special issue at this moment.
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