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Biosensors
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Cellulose-Based Biosensing Platforms, Volume II
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Cellulose-Based Biosensing Platforms, Volume II

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 6639

Special Issue Editors

Prof. Dr. Eden Morales-Narváez

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Guest Editor
Biophotonic Nanosensors Laboratory, Center for Applied Physics and Advanced Technology, National Autonomous University of Mexico (Universidad Nacional Autónoma de México, UNAM), Juriquilla, Queretaro, Mexico
Interests: biophotonics; optically active nanomaterials; graphene and 2D materials; wearable devices; point of care devices; biosensors; nanocomposites; microarray technology; in vitro diagnostics
Special Issues, Collections and Topics in MDPI journals
Dr. Alfredo de la Escosura-Muñiz

E-Mail Website
Guest Editor
Nanobioanalysis Group, Department of Physical and Analytical Chemistry, University of Oviedo, Oviedo, Spain
Interests: nanobiosensors; lateral flow analysis; electrochemical biosensors; electrocatalysis; nanochannels
Special Issues, Collections and Topics in MDPI journals
Dr. Erhan Zor

E-Mail Website
Guest Editor
Department of Science Education, A. K. Education Faculty, Necmettin Erbakan University, Konya 42090, Turkey
Interests: graphene; nanocellulose; biosensors; chiral sensors; optical sensors, electrochemical sensors, paper-based diagnostics; biomedical diagnostics
Special Issues, Collections and Topics in MDPI journals
Dr. Hamed Golmohammadi

E-Mail Website
Guest Editor
Nanosensor Bioplatforms Laboratory, Chemistry and Chemical Engineering Research Center of Iran, Tehran 14335-186, Iran
Interests: (nano)paper-based sensors; optical biosensing; Smartphone IoT-based sensors; wearable sensors; point-of-care devices; ingestible sensors; cellulose-based microfluidics; optical sensor array; nature-based (nano)materials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As the most abundant renewable biopolymer in nature, cellulose is a convenient family of materials to design low-cost devices. In addition, cellulose-based materials are flexible, biocompatible, biodegradable, and amenable to straightforward functionalization, as well as mass production. These unrivaled features of cellulosic substrates—including paper, textile/thread and nanocellulose—and their fascinating simplicity of fabrication and coupling with ubiquitous technologies such as smartphones make them tailor-made biosensing platforms. Furthermore, cellulose-based biosensing approaches can meet the World Health Organization’s REASSURED (real-time connectivity, ease of specimen collection, affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and deliverable to end-users) criteria for ideal diagnostic assays/devices. Hence, cellulose endows the biosensing community with exquisite materials to envisage innovative analytical devices.

You can find information about Special Issue—Part I at https://www.mdpi.com/journal/biosensors/special_issues/cellulose_bio. Special Issue—Part II will continue to focus on cutting-edge approaches dealing with the design, fabrication, and advantageous analytical performance of cellulose-based biosensing platforms, including but not limited to paper, textile/thread, and nanocellulose-based biosensing technology. The applications portfolio may embrace medical/clinical diagnostics, healthcare, point-of-care testing, environmental monitoring, food analysis, or other biochemical and biological analyses.

We invite you to contribute full papers, reviews, or communications to this Special Issue. In all cases, the papers must demonstrate originality and be relevant to the scope of this issue.

Prof. Dr. Eden Morales-Narváez
Dr. Alfredo de la Escosura-Muñiz
Dr. Erhan Zor
Dr. Hamed Golmohammadi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • bioplatforms
  • biosensors
  • cellulose-based microfluidics
  • diagnostics
  • electronic textiles
  • environmental monitoring
  • food analysis
  • healthcare
  • lateral flow immunoassay
  • micro/nanocellulose fibrils
  • multiplexed detection
  • nano/composite materials
  • nanocellulose
  • on-site detection
  • paper cutting
  • paper-based analytical devices
  • photolithography
  • point-of-care devices
  • point-of-care testing
  • portable devices
  • preventive health care
  • smartphone and paper-based biosensors
  • textile-based biosensors
  • thread-based biosensors
  • wax/inkjet/screen printing
  • wearable sensors
  • (nano)cellulose-based biosensors
  • 3D-printed paper-based microfluidics

Published Papers (3 papers)

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Research

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13 pages, 2677 KiB  
Article
A Paper-Based Biomimetic Sensing Device for the Discrimination of Original and Fraudulent Cigarette Brands Using Mixtures of MoS2 Quantum Dots and Organic Dyes
by Fereshte Mohamadi Gharaghani, Sara Mostafapour and Bahram Hemmateenejad
Biosensors 2023, 13(7), 705; https://doi.org/10.3390/bios13070705 - 04 Jul 2023
Cited by 1 | Viewed by 1036
Abstract
In this study, we investigated the combined effects of MoS2 QDs’ catalytic properties and the colorimetric responses of organic reagents to create a sniffing device based on the sensor array concept of the mammalian olfactory system. The aim was to differentiate the [...] Read more.
In this study, we investigated the combined effects of MoS2 QDs’ catalytic properties and the colorimetric responses of organic reagents to create a sniffing device based on the sensor array concept of the mammalian olfactory system. The aim was to differentiate the volatile organic compounds (VOCs) present in cigarette smoke. The designed optical nose device was utilized for the classification of various cigarette VOCs. Unsupervised Principal Component Analysis (PCA) and supervised Linear Discriminant Analysis (LDA) methods were employed for data analysis. The LDA analysis showed promising results, with 100% accuracy in both training and cross-validation. To validate the sensor’s performance, we assessed its ability to discriminate between five cigarette brands, achieving 100% accuracy in the training set and 82% in the cross-validation set. Additionally, we focused on studying four popular Iranian cigarette brands (Bahman Kootah, Omega, Montana Gold, and Williams), including fraudulent samples. Impressively, the developed sensor array achieved a perfect 100% accuracy in distinguishing these brands and detecting fraud. We further analyzed a total of 126 cigarette samples, including both original and fraudulent ones, using LDA with a matrix size of (126 × 27). The resulting LDA model demonstrated an accuracy of 98%. Our proposed analytical procedure is characterized by its efficiency, affordability, user-friendliness, and reliability. The selectivity exhibited by the developed sensor array positions it as a valuable tool for differentiating between original and counterfeit cigarettes, thus aiding in border control efforts worldwide. Full article
(This article belongs to the Special Issue Cellulose-Based Biosensing Platforms, Volume II)
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Review

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32 pages, 16428 KiB  
Review
Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module
by Rohini Kumari, Akanksha Singh, Uday Pratap Azad and Pranjal Chandra
Biosensors 2023, 13(9), 891; https://doi.org/10.3390/bios13090891 - 19 Sep 2023
Viewed by 1882
Abstract
Over the past ten years, microfluidic paper-based analytical devices (micro-PADs) have attracted a lot of attention as a viable analytical platform. It is expanding as a result of advances in manufacturing processes and device integration. Conventional microfluidics approaches have some drawbacks, including high [...] Read more.
Over the past ten years, microfluidic paper-based analytical devices (micro-PADs) have attracted a lot of attention as a viable analytical platform. It is expanding as a result of advances in manufacturing processes and device integration. Conventional microfluidics approaches have some drawbacks, including high costs, lengthy evaluation times, complicated fabrication, and the necessity of experienced employees. Hence, it is extremely important to construct a detection system that is quick, affordable, portable, and efficient. Nowadays, micro-PADs are frequently employed, particularly in electrochemical analyses, to replicate the classic standard laboratory experiments on a miniature paper chip. It has benefits like rapid assessment, small sample consumption, quick reaction, accuracy, and multiplex function. The goal of this review is to examine modern paper microfluidics-based electrochemical sensing devices for the detection of macromolecules, small molecules, and cells in a variety of real samples. The design and fabrication of micro-PADs using conventional and the latest techniques have also been discussed in detail. Lastly, the limitations and potential of these analytical platforms are examined in order to shed light on future research. Full article
(This article belongs to the Special Issue Cellulose-Based Biosensing Platforms, Volume II)
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17 pages, 2080 KiB  
Review
Lateral Flow Assay: A Summary of Recent Progress for Improving Assay Performance
by Kobra Omidfar, Fatemeh Riahi and Soheila Kashanian
Biosensors 2023, 13(9), 837; https://doi.org/10.3390/bios13090837 - 23 Aug 2023
Cited by 8 | Viewed by 3002
Abstract
Lateral flow tests are one of the most important types of paper-based point-of-care (POCT) diagnostic tools. It shows great potential as an implement for improving the rapid screening and management of infections in global pandemics or other potential health disorders by using minimally [...] Read more.
Lateral flow tests are one of the most important types of paper-based point-of-care (POCT) diagnostic tools. It shows great potential as an implement for improving the rapid screening and management of infections in global pandemics or other potential health disorders by using minimally expert staff in locations where no sophisticated laboratory services are accessible. They can detect different types of biomarkers in various biological samples and provide the results in a little time at a low price. An important challenge regarding conventional LFAs is increasing their sensitivity and specificity. There are two main approaches to increase sensitivity and specificity, including assay improvement and target enrichment. Assay improvement comprises the assay optimization and signal amplification techniques. In this study, a summarize of various sensitivity and specificity enhancement strategies with an objective evaluation are presented, such as detection element immobilization, capillary flow rate adjusting, label evolution, sample extraction and enrichment, etc. and also the key findings in improving the LFA performance and solving their limitations are discussed along with numerous examples. Full article
(This article belongs to the Special Issue Cellulose-Based Biosensing Platforms, Volume II)
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