Dear Colleagues,

I am very pleased to invite you to contribute to this Special Issue on Recent Progress in Biosensor Technologies for the Detection of Exosomes. Exosomes are extracellular vesicles (generally with a length of 30-150 nm) that play important roles in various physiological and pathological processes. These cell-secreted nanoparticles are considered a special class of biomarkers for non-invasive disease diagnostics in point-of-care settings.

Biosensors have gained great research attention for the detection of exosomes due to their superior properties, such as convenient operation, real-time monitoring ability, high sensitivity, and remarkable specificity. They have great potential in various biomedical applications (from early diagnosis to therapy monitoring), e.g., the early diagnosis of cancer. Exosomes are attractive cancer biomarkers in noninvasive early diagnosis because of their unique physiological and pathological functions, which can reveal remarkable information about cancer microenvironments and plays an important role in the development and evolution of cancer.

The rapid developments of exosomes biosensors, such as concepts in structural design, fabrication techniques, sensing materials, numerical simulations, sensing techniques (optical, electrochemical, microfluidics and electrical (nano) biosensors for detection of exosomes) and diagnostic applications are significantly contributing to this field for the development of an accurate and highly sensitive detection platform for future clinical applications.

This Special Issue, entitled “Recent Progress in Biosensor Technologies for Detection of Exosomes”, will showcase the recent advances in exosomes biosensing and investigate the current challenges, recommendations and future opportunities in this field.

The editors of this Special Issue welcome original research and review articles that cover both exosome bioengineering and their biosensing applications, achieving the goal of presenting challenges in cancer biosensing and detecting trace amounts of a wide variety of analytes. This Special Issue plans not only to provide an overview of recent achievements but also to stimulate ideas about current and future research in exosome sensors in the field of translational bioengineering.

Prof. Dr. Nan-Fu Chiu
Dr. Yu-Sheng Hsiao
Dr. Yun-Ju Lai
Dr. Himansu Sekhar Nanda
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• exosomes
• micro-RNA
• biosensors
• diagnostic applications
• clinical applications
• translational bioengineering