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Biosensors
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Women in Biosensors (Volume II)
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Women in Biosensors (Volume II)

A special issue of Biosensors (ISSN 2079-6374).

Deadline for manuscript submissions: 30 September 2024 | Viewed by 7042

Special Issue Editors

Prof. Dr. Cecilia Cristea

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Guest Editor
Department of Analytical Chemistry, Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 4 Pasteur Street, 400349 Cluj-Napoca, Romania
Interests: electrochemical and optical sensors; graphene; nanomaterials based electrodes; bioanalysis
Special Issues, Collections and Topics in MDPI journals
Dr. Andreea Cernat

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Guest Editor
Analytical Chemistry Department, Faculty of Pharmacy, Iuliu Haţieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
Interests: (bio)electrochemistry
Prof. Dr. Jolanta Kochana

E-Mail Website
Guest Editor
Department of Analytical Chemistry, Faculty of Chemistry of the Jagiellonian University, Krakow, Poland
Interests: analytical chemistry; sensors and biosensors; electroanalysis; pharmaceutical; biomedical and environmental analysis; nanomaterials;

Special Issue Information

Dear Colleagues,

To celebrate and highlight the achievements of women in biosensors research, a Special Issue entitled “Women in Biosensors (Volume II)” is being launched, which will present biosensors-related work from leading women scientists. We hope that this Special Issue can further encourage and promote the scientific contributions of women researchers in this field.

This Special Issue welcomes both research and review papers on the most recent and innovative developments of biosensors for applications in the food, health, security, defense, and environmental fields. To be considered for this Special Issue, the corresponding author should be a woman scientist.

Prof. Dr. Cecilia Cristea
Dr. Andreea Cernat
Prof. Dr. Jolanta Kochana
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (4 papers)

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Research

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10 pages, 3124 KiB  
Communication
Graphene-Based Metamaterial Sensor for Pesticide Trace Detection
by Tingting Lang, Meiyu Xiao and Wenyang Cen
Biosensors 2023, 13(5), 560; https://doi.org/10.3390/bios13050560 - 19 May 2023
Cited by 5 | Viewed by 1674
Abstract
Organophosphate insecticides with broad spectrum and high efficiency make a great difference to agricultural production. The correct utilization and residue of pesticides have always been important issues of concern, and residual pesticides can accumulate and pass through the environment and food cycle, resulting [...] Read more.
Organophosphate insecticides with broad spectrum and high efficiency make a great difference to agricultural production. The correct utilization and residue of pesticides have always been important issues of concern, and residual pesticides can accumulate and pass through the environment and food cycle, resulting in safety and health hazards to humans and animals. In particular, current detection methods are often characterized by complex operations or low sensitivity. Fortunately, using monolayer graphene as the sensing interface, the designed graphene-based metamaterial biosensor working in the 0–1 THz frequency range can achieve highly sensitive detection characterized by spectral amplitude changes. Meanwhile, the proposed biosensor has the advantages of easy operation, low cost, and quick detection. Taking phosalone as an example, its molecules can move the Fermi level of graphene with π–π stacking, and the lowest concentration of detection in this experiment is 0.01 μg/mL. This metamaterial biosensor has great potential in detecting trace pesticides, and its application in food hygiene and medicine can provide better detection services. Full article
(This article belongs to the Special Issue Women in Biosensors (Volume II))
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Review

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42 pages, 4165 KiB  
Review
Extremozyme-Based Biosensors for Environmental Pollution Monitoring: Recent Developments
by Cristina Purcarea, Robert Ruginescu, Roberta Maria Banciu and Alina Vasilescu
Biosensors 2024, 14(3), 143; https://doi.org/10.3390/bios14030143 - 14 Mar 2024
Viewed by 925
Abstract
Extremozymes combine high specificity and sensitivity with the ability to withstand extreme operational conditions. This work presents an overview of extremozymes that show potential for environmental monitoring devices and outlines the latest advances in biosensors utilizing these unique molecules. The characteristics of various [...] Read more.
Extremozymes combine high specificity and sensitivity with the ability to withstand extreme operational conditions. This work presents an overview of extremozymes that show potential for environmental monitoring devices and outlines the latest advances in biosensors utilizing these unique molecules. The characteristics of various extremozymes described so far are presented, underlining their stability and operational conditions that make them attractive for biosensing. The biosensor design is discussed based on the detection of photosynthesis-inhibiting herbicides as a case study. Several biosensors for the detection of pesticides, heavy metals, and phenols are presented in more detail to highlight interesting substrate specificity, applications or immobilization methods. Compared to mesophilic enzymes, the integration of extremozymes in biosensors faces additional challenges related to lower availability and high production costs. The use of extremozymes in biosensing does not parallel their success in industrial applications. In recent years, the “collection” of recognition elements was enriched by extremozymes with interesting selectivity and by thermostable chimeras. The perspectives for biosensor development are exciting, considering also the progress in genetic editing for the oriented immobilization of enzymes, efficient folding, and better electron transport. Stability, production costs and immobilization at sensing interfaces must be improved to encourage wider applications of extremozymes in biosensors. Full article
(This article belongs to the Special Issue Women in Biosensors (Volume II))
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16 pages, 2304 KiB  
Review
Nanophotonic Enhanced Chiral Sensing and Its Biomedical Applications
by Fei Wang, Xue Wang, Xinchao Lu and Chengjun Huang
Biosensors 2024, 14(1), 39; https://doi.org/10.3390/bios14010039 - 12 Jan 2024
Viewed by 1373
Abstract
Chiral sensing is crucial in the fields of biology and the pharmaceutical industry. Many naturally occurring biomolecules, i.e., amino acids, sugars, and nucleotides, are inherently chiral. Their enantiomers are strongly associated with the pharmacological effects of chiral drugs. Owing to the extremely weak [...] Read more.
Chiral sensing is crucial in the fields of biology and the pharmaceutical industry. Many naturally occurring biomolecules, i.e., amino acids, sugars, and nucleotides, are inherently chiral. Their enantiomers are strongly associated with the pharmacological effects of chiral drugs. Owing to the extremely weak chiral light–matter interactions, chiral sensing at an optical frequency is challenging, especially when trace amounts of molecules are involved. The nanophotonic platform allows for a stronger interaction between the chiral molecules and light to enhance chiral sensing. Here, we review the recent progress in nanophotonic-enhanced chiral sensing, with a focus on the superchiral near-field and enhanced circular dichroism (CD) spectroscopy generated in both the dielectric and in plasmonic structures. In addition, the recent applications of chiral sensing in biomedical fields are discussed, including the detection and treatment of difficult diseases, i.e., Alzheimer’s disease, diabetes, and cancer. Full article
(This article belongs to the Special Issue Women in Biosensors (Volume II))
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28 pages, 3530 KiB  
Review
Recent Progress of Electrochemical Aptasensors toward AFB1 Detection (2018–2023)
by Despina Ciobanu, Oana Hosu-Stancioiu, Gheorghe Melinte, Flavia Ognean, Ioan Simon and Cecilia Cristea
Biosensors 2024, 14(1), 7; https://doi.org/10.3390/bios14010007 - 22 Dec 2023
Viewed by 1401
Abstract
Food contaminants represent possible threats to humans and animals as severe food safety hazards. Prolonged exposure to contaminated food often leads to chronic diseases such as cancer, kidney or liver failure, immunosuppression, or genotoxicity. Aflatoxins are naturally produced by strains of the fungi [...] Read more.
Food contaminants represent possible threats to humans and animals as severe food safety hazards. Prolonged exposure to contaminated food often leads to chronic diseases such as cancer, kidney or liver failure, immunosuppression, or genotoxicity. Aflatoxins are naturally produced by strains of the fungi species Aspergillus, which is one of the most critical and poisonous food contaminants worldwide. Given the high percentage of contaminated food products, traditional detection methods often prove inadequate. Thus, it becomes imperative to develop fast, accurate, and easy-to-use analytical methods to enable safe food products and good practices policies. Focusing on the recent progress (2018–2023) of electrochemical aptasensors for aflatoxin B1 (AFB1) detection in food and beverage samples, without pretending to be exhaustive, we present an overview of the most important label-free and labeled sensing strategies. Simultaneous and competitive aptamer-based strategies are also discussed. The aptasensors are summarized in tabular format according to the detection mode. Sample treatments performed prior analysis are discussed. Emphasis was placed on the nanomaterials used in the aptasensors’ design for aptamer-tailored immobilization and/or signal amplification. The advantages and limitations of AFB1 electrochemical aptasensors for field detection are presented. Full article
(This article belongs to the Special Issue Women in Biosensors (Volume II))
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