Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.9
5.4
Journals
Biosensors
Special Issues
Microfluidic-Based Biosensors for Point-of-Care Diagnostics
share announcement

Microfluidic-Based Biosensors for Point-of-Care Diagnostics

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 2217

Special Issue Editors

Dr. Mazhar Sher

E-Mail Website
Guest Editor
Department of Agricultural and Biosystems Engineering, South Dakota State University, Brookings, SD 57007, USA
Interests: POC diagnostics; microfluidic devices; biosensors
Special Issues, Collections and Topics in MDPI journals
Dr. Ran An

E-Mail Website
Guest Editor
Department of Biomedical Engineering, University of Houston, Houston, TX 77204-4005, USA
Interests: microfluidics; electrokinetics; point-of-care; biosensing; organ on a chip
Special Issues, Collections and Topics in MDPI journals
Dr. Azahar Ali

E-Mail Website
Guest Editor
Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
Interests: microfluidic devices; advanced manufacturing; biosensors; nanomaterials; precision agriculture; livestock sensing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The aim of microfluidic-based biosensors is to provide rapid, cost-effective, easy-to-use, portable, and accurate diagnostic tools for resource-limited settings. The integration of microfluidic technology with biosensors facilitates real-time assays using smaller sample volumes. Lab-based tests can be performed using such biosensors at home and in other POC settings. This can have revolutionizing impact in the healthcare sector.

Microfluidic-based biosensors have broad scope as such sensors can detect various analytes such as proteins, nucleic acids, and small molecules. It is also possible to utilize these sensors for pathogen detection. These microfluidic-based biosensors can also be used to monitor the progression of disease and treatment monitoring.  This special issue seeks articles on the recent developments in the area of microfluidic-based biosensors for POC disease diagnostic applications.

Dr. Mazhar Sher
Dr. Ran An
Dr. Azahar Ali
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microfluidics
  • biosensors
  • point-of-care testing
  • disease diagnostics
  • treatment monitoring
  • rapid testing
  • resource-constrained settings

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Other

11 pages, 1673 KiB  
Brief Report
Point-of-Care Diagnostic Test for Beta-Thalassemia
by Ran An, Alireza Avanaki, Priyaleela Thota, Sai Nemade, Amrish Mehta and Umut A. Gurkan
Biosensors 2024, 14(2), 83; https://doi.org/10.3390/bios14020083 - 02 Feb 2024
Viewed by 1864
Abstract
Hemoglobin (Hb) disorders are among the most common monogenic diseases affecting nearly 7% of the world population. Among various Hb disorders, approximately 1.5% of the world population carries β-thalassemia (β-Thal), affecting 40,000 newborns every year. Early screening and a timely [...] Read more.
Hemoglobin (Hb) disorders are among the most common monogenic diseases affecting nearly 7% of the world population. Among various Hb disorders, approximately 1.5% of the world population carries β-thalassemia (β-Thal), affecting 40,000 newborns every year. Early screening and a timely diagnosis are essential for β-thalassemia patients for the prevention and management of later clinical complications. However, in Africa, Southern Europe, the Middle East, and Southeast Asia, where β-thalassemia is most prevalent, the diagnosis and screening for β-thalassemia are still challenging due to the cost and logistical burden of laboratory diagnostic tests. Here, we present Gazelle, which is a paper-based microchip electrophoresis platform that enables the first point-of-care diagnostic test for β-thalassemia. We evaluated the accuracy of Gazelle for the β-Thal screening across 372 subjects in the age range of 4–63 years at Apple Diagnostics lab in Mumbai, India. Additionally, 30 blood samples were prepared to mimic β-Thal intermediate and β-Thal major samples. Gazelle-detected levels of Hb A, Hb F, and Hb A2 demonstrated high levels of correlation with the results reported through laboratory gold standard high-performance liquid chromatography (HPLC), yielding a Pearson correlation coefficient = 0.99. This ability to obtain rapid and accurate results suggests that Gazelle may be suitable for the large-scale screening and diagnosis of β-Thal. Full article
(This article belongs to the Special Issue Microfluidic-Based Biosensors for Point-of-Care Diagnostics)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop