Biophysical Studies of Metalloproteins

A special issue of Biophysica (ISSN 2673-4125).

Deadline for manuscript submissions: 28 August 2024 | Viewed by 145

Special Issue Editor

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Guest Editor
Dipartimento di Scienze biochimiche ‘A. Rossi Fanelli’, Università degli Studi di Roma La Sapienza, Rome, Italy
Interests: iron; copper; multicopper oxidase; ceruloplasmin; ferroportin; lactoferrin; neurodegeneration; oxidative stress; yeast; membrane proteins
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Special Issue Information

Dear Colleagues,

Metal ions play a critical role as structural, catalytic and signaling components of proteins in all living organisms. Metalloproteins can bind single or multiple metals in the form of simple ions, clusters or with cofactors of varying complexity. Transition metals such as Fe, Cu, Mn and the post-transition metal Zn, are involved in a remarkably wide variety of cellular processes, ranging from respiration to photosynthesis, nitrogen fixation, the Krebs cycle, oxygen transport, antioxidant defense, DNA synthesis, gene regulation among others. Other transition metals such as Co, Mo, Ni, V and W are much less frequent in proteins but nevertheless they too are essential for key biochemical reactions in all kingdoms of life. Metal coordination and chemistry shapes protein structure and function, so it is not surprising that defects in metal homeostasis (either due to excess or deficiency) often lead to pathological states.

This Special Issue of Biophysica welcomes contributions in all areas of metalloprotein biophysics: relation between molecular structure, mechanism and function, metal-mediated regulation and signaling, biophysical techniques for the study of metalloproteins. Original papers and review articles on these and related topics are welcome.

Dr. Maria Carmela Bonaccorsi Di Patti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biophysica is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • transition metals
  • metal clusters
  • structure
  • catalysis
  • regulation
  • electron transfer
  • metalloenzymes
  • metal transporters
  • metal sensors
  • heavy metal toxicity

Published Papers

This special issue is now open for submission.
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