Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mechanisms and Novel Biomarkers Underlying Aging and Longevity
edited by Ines Sanchez-Roman and
submission deadline 31 May 2024 | 2 articles | Viewed by 2533 | Submission Open
Keywords: aging; genomic instability; mitochondrial dysfunction; oxidative stress; premature aging; longevity; aging-associated diseases; interventions
(This special issue belongs to the Section Molecular Biomarkers)
Recent Developments in Mesenchymal Stem Cells submission deadline 31 May 2024 | 2 articles | Viewed by 1939 | Submission Open
Keywords: mesenchymal stromal cell; regenerative medicine; secretome
(This special issue belongs to the Section Cellular Biochemistry)
Biophotonic Techniques in Biological Molecules, Cells and Tissues: New Advances and Future Trends
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1329 | Submission Open
Keywords: biophotonics; optogenetics; lasers; diagnosis; image; therapy
(This special issue belongs to the Section Biological and Bio- Materials)
Recent Insights into Metal Binding Proteins
edited by Pedro Tavares and Alice S. Pereira
submission deadline 31 May 2024 | 1 articles | Viewed by 971 | Submission Open
Keywords: metal-binding proteins; metalloproteins; metalloenzymes; metal homeostasis
(This special issue belongs to the Section Biomacromolecules: Proteins)
Targeting Neuroinflammation and Insulin Resistance for a Healthy Brain: Prevention and Treatment of Neurological and Psychiatric Disorders submission deadline 31 May 2024 | Viewed by 367 | Submission Open
Keywords: insulin receptor substrates; microglia; degenerative diseases; psychiatric disorders; nutrition
(This special issue belongs to the Section Molecular Medicine)
Targeting Sodium Channels and Pumps for Cancer Therapy
edited by
submission deadline 31 May 2024 | Viewed by 193 | Submission Open
Keywords: carcinomas; voltage-gated sodium channels; Na+; K+-ATPase
(This special issue belongs to the Section Molecular Medicine)
Cannabinoid Receptors in the Central Nervous System
edited by
submission deadline 31 May 2024 | Viewed by 147 | Submission Open
Keywords: learning and memory; endocannabinoid system; cognitive flexibility; cerebellum; hippocampus
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
New Insights into RNA-Binding Proteins
edited by
submission deadline 31 May 2024 | Viewed by 95 | Submission Open
Keywords: RNA-binding protein; RBP; RNA; riboregulation; RNA interactome; protein– RNA interaction; protein– RNA complex; ribonucleoprotein
(This special issue belongs to the Section Biomacromolecules: Proteins)
Molecular Advances in Inflammatory Bowel Disease submission deadline 1 Jun 2024 | Viewed by 185 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; biologics; quality of life; diagnostic markers; prognostic markers; drug monitoring; antibodies
(This special issue belongs to the Section Molecular Medicine)
Exploring the Dynamics of Protein Lysine Methylation and Its Implication in Disease
edited by Kyle K. Biggar
submission deadline 1 Jun 2024 | Viewed by 91 | Submission Open
Keywords: protein regulation; disease mechanisms; biomarkers and therapeutic targets; cellular signaling; mass spectrometry
(This special issue belongs to the Section Biomacromolecules: Proteins)
The Physiological and Pathological New Function of Mitochondrial ROS and Intraorganellar Cross-Talks Part II submission deadline 3 Jun 2024 | 2 articles | Viewed by 3891 | Submission Open
Keywords: mitochondrial ROS; cellular signaling;   intraorganellar cross-talks; mito-nuclear communication; mitochondrial antioxidant; aging
(This special issue belongs to the Section Molecular Structure and Dynamics)
Role of Neuron-Glia and Glia-Glia Communications in the Brain Function: Recent Advances in the Central Nervous System Cellular Crosstalk and Signaling
edited by
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1724 | Submission Open
Keywords: glia-glia interactions; neuron-glia interactions; CNS cell– cell communication; neuroinflammation; neurodegeneration
(This special issue belongs to the Section Cellular Biochemistry)
New Insights into Diagnostic and Prognostic Biomarkers of Amyotrophic Lateral Sclerosis: Must Innovative Findings Come from New Targets?
edited by Hélène Blasco
submission deadline 15 Jun 2024 | Viewed by 212 | Submission Open
Keywords: biomarkers; omics; animal models; innovation
(This special issue belongs to the Section Molecular Biomarkers)
Inositol Phosphates in Health and Disease - Volume II
edited by and
submission deadline 20 Jun 2024 | 2 articles | Viewed by 2348 | Submission Open
Keywords: inositol polyphosphates (IPs); IP6; inositol pyrophosphate (PP-Ips); signal transduction; energy metabolism; anticancer activity; PCOS; metabolic diseases; pathological calcification; neuropsychiatric disease
(This special issue belongs to the Section Molecular Medicine)
Breast Cancer: Molecular Mechanisms and Targeted Therapies
edited by
submission deadline 20 Jun 2024 | Viewed by 117 | Submission Open
Keywords: breast cancer; breast cancer metastasis; cancer metabolism; molecular and cellular basis of breast cancer; chemoresistance in breast cancer; triple-negative breast cancer and breast cancer stem cell
(This special issue belongs to the Section Molecular Medicine)
More than Just Adhesion: Recognition Molecules, a Theme Issue Honoring Professor Melitta Schachner
edited by
submission deadline 25 Jun 2024 | 1 articles | Viewed by 2023 | Submission Open
Keywords: cell adhesion molecules; extracellular matrix; glycans; nervous system regeneration; nervous system development
(This special issue belongs to the Section Biological Factors)
Unveiling Protein Functions, Dynamics and Interactions in Health and Disease Using Experimental and Theoretical Approaches
edited by , Cristina Maracci, Alice Romagnoli and
submission deadline 30 Jun 2024 | 9 articles | Viewed by 24960 | Submission Open
Keywords: Protein’ s structure and dynamics; Protein-protein interactions; Point mutations; Molecular biology; Molecular modelling; Molecular dynamics; Biochemistry; Bioinformatics; Protein-ligand interaction; Protein-nucleic acids interaction; Protein’ s conformational changes
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Melatonin in Health and Disease submission deadline 30 Jun 2024 | 5 articles | Viewed by 20530 | Submission Open
Keywords: melatonin; melatonin receptors; pineal gland; chronobiology
(This special issue belongs to the Section Molecular Medicine)
Redox Imbalance and Mitochondrial Abnormalities in Kidney Disease II
edited by
submission deadline 30 Jun 2024 | 8 articles | Viewed by 20139 | Submission Open
Keywords: acute kidney injury; chronic kidney disease; diabetic nephropathy; diabetic kidney disease; redox imbalance; reductive stress; reactive oxygen species; oxidative stress; mitochondrial abnormalities; mitochondrial homeostasis; mitophagy; unfolded protein response
(This special issue belongs to the Section Molecular Medicine)
Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants
edited by
submission deadline 30 Jun 2024 | 7 articles | Viewed by 10995 | Submission Open
Keywords: cells; humans; animals; plants; microorganisms; microgravity; weightlessness; cancer research; tissue engineering; space-related health problems
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Basis and Translational Research in Metabolic Myopathies: A Themed Issue in Honor of Professor Corrado Angelini submission deadline 30 Jun 2024 | 5 articles | Viewed by 10748 | Submission Open
Keywords: metabolic myopathies; lipid metabolism; glycogen metabolism; genetic diseases; treatments; lipid storage myopathies; glycogen storage myopathies; lysosomal storage myopathies
(This special issue belongs to the Section Molecular Biology)
Fibrodysplasia Ossificans Progressiva (FOP): From Molecular Mechanisms to Therapeutic Strategies submission deadline 30 Jun 2024 | 7 articles | Viewed by 9482 | Submission Open
Keywords: fibrodysplasia ossificans progressiva; bone morphogenetic protein (BMP); signaling pathway; ACVR1; fibro/adipogenic progenitor cells (FAPs); heterotopic ossification
(This special issue belongs to the Section Molecular Medicine)
Immune-Related Biomarkers II submission deadline 30 Jun 2024 | 8 articles | Viewed by 8796 | Submission Open
Keywords: immune biomarker; proteomics; O-link; molecular medicine; prediction of disease; diagnosis/stratification of diseases; targeted immune therapy
(This special issue belongs to the Section Molecular Biomarkers)
Insights of Innate Immunology into Inflammation and Infections
edited by , Bo Liu and
submission deadline 30 Jun 2024 | 3 articles | Viewed by 7939 | Submission Open
Keywords: innate immunity; innate immune cells; inflammation; infection
(This special issue belongs to the Section Molecular Medicine)
Eosinophils in Allergy and Related Diseases—Selected Papers from “The Workshop on Eosinophils in Allergy and Related Diseases 2022” submission deadline 30 Jun 2024 | 5 articles | Viewed by 7103 | Submission Open
Keywords: allergic inflammation; asthma; atopic dermatitis; allergic rhinitis; allergic conjunctivitis; chronic rhinosinusitis with nasal polyp (CRSwNP); eosinophils; eosinophilic pneumonia; eosinophilic chronic rhinosinusitis (ECRS); eosinophilic gastrointestinal diseases (EGIDs); hypereosinophilic syndromes (HESs); eosinophilic granulomatosis with polyangiitis (EGPA)
(This special issue belongs to the Section Molecular Medicine)
DNA Damage and DNA Repair in Cancer submission deadline 30 Jun 2024 | 5 articles | Viewed by 7076 | Submission Open
Keywords: DNA damage; DNA repair; cancer; therapy; radiation biology; systems biology
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Sowing the Seed to Ensure the Future of Plant Proteomics: Commemorative Issue in Honor of Dr. Dominique Job (1947–2022) submission deadline 30 Jun 2024 | 6 articles | Viewed by 6649 | Submission Open
Keywords: model and non-model plant species; crops; forestry; horticulture; ecology; flowering; floral induction; biennial bearing; fruit load; seed physiology; seed metabolism; seed germination; seed vigor; seed viability; seed longevity; desiccation tolerance; dormancy; post-genomics and omics; transcriptomics; proteomics; secretomics; systems biology; biotic stress; plant-microbe interactions (bacteria; fungi; viruses); abiotic stress; oxidative stress and reactive oxygen species (ROS); sulfur metabolism (biotin; Cys; Met; S-AdoMet; protein biotinylation); drought tolerance; post-translational modifications (PTMs); protein turnover; big data; data integration; data mining
(This special issue belongs to the Section Molecular Biology)
Histone Modifications in Health and Diseases
edited by , and Yuning Hou
submission deadline 30 Jun 2024 | 3 articles | Viewed by 6516 | Submission Open
Keywords: histone modifications; lysine methylation; lysine acetylation; histone phosphorylation; histone ubiquitylation; histone sumoylation; human diseases
(This special issue belongs to the Section Biomacromolecules: Proteins)
Brain Sterols: Biosynthesis and Physiology in Health and Disease submission deadline 30 Jun 2024 | 4 articles | Viewed by 6022 | Submission Open
Keywords: sterol biosynthesis; sterol turnover; oxysterol; brain; cholesterol; development; aging; medication side effects; inborn errors of sterol biosynthesis; DHCR7
(This special issue belongs to the Section Synthetic Biology and Bioengineering)
RNA Therapeutics
edited by
submission deadline 30 Jun 2024 | 2 articles | Viewed by 5634 | Submission Open
Keywords: antisense oligonucleotides (ASO); siRNA; mRNA new chemistries; therapeutic targets/indications; cellular delivery/endosomal escape (LNPs/CPPs); in vivo administration/formulation/efficacy; tissue targeting/PK/PD
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Biomarkers for Pancreatitis and Its Complications submission deadline 30 Jun 2024 | 4 articles | Viewed by 5314 | Submission Open
Keywords: acute pancreatitis; recurrent acute pancreatitis; chronic pancreatitis; pancreatic cancer; diagnostic biomarkers; biomarkers of severity; prognostic biomarkers
(This special issue belongs to the Section Molecular Biomarkers)
Advances in Protein-Ligand Interactions: From Structure, Function to Applications
edited by
submission deadline 30 Jun 2024 | 4 articles | Viewed by 4905 | Submission Open
Keywords: bioinformatics; compound libraries; computational biology; de novo drug design; drug discovery; ligand binding; machine learning; molecular docking; molecular dynamics; protein complexes
(This special issue belongs to the Section Molecular Structure and Dynamics)
Recent Advances in Neurological Diseases
edited by Sara Carpi, and
submission deadline 30 Jun 2024 | 3 articles | Viewed by 4106 | Submission Open
Keywords: neurological disorders; neurodegeneration; neuroinflammation; myelin damage; developmental disorders; epilepsy; neurodegenerative rare diseases; neuromuscular diseases; lipid storage diseases; psychiatric diseases
(This special issue belongs to the Section Molecular Medicine)
Early Adversity and the Immune Hypothesis: Call for a Dialogue between Basic and Clinical Neuroscience
edited by Arie Kaffman, Kate Ryan Kuhlman, Bridget L. Callaghan and Christine Heim
submission deadline 30 Jun 2024 | 4 articles | Viewed by 3728 | Submission Open
Keywords: early adversity; microglia; neuroinflammation; microbiome; psychopathology
(This special issue belongs to the Section Molecular Biology)
Hyaluronic Acid and Proteoglycans: Basic and Biomedical Applications
edited by
submission deadline 30 Jun 2024 | 3 articles | Viewed by 3193 | Submission Open
Keywords: hyaluronic acid; proteoglycans; GAGs; extracellular matrix; hyaluronic acid and proteoglycans in disease; cancer; inflammation; angiogenesis; vascular homeostasis and damage; arthritis and arthrosis; glycobiology
(This special issue belongs to the Section Biomacromolecules: Carbohydrates)
Novel Insights into Cytochrome P450 Enzymes in Drug Metabolism
edited by and Lionel Cheruzel
submission deadline 30 Jun 2024 | 3 articles | Viewed by 3104 | Submission Open
Keywords: P450 enzymes; oxidative metabolism; drug– drug interactions; exhepatic P450; bioactivation
Melatonin in Normal Physiology and Disease
edited by
submission deadline 30 Jun 2024 | 2 articles | Viewed by 3083 | Submission Open
Keywords: circadian rhythms; immunity; skin; reproduction; aging; viral and bacterial infection; inflammation; mesenchymal stem cells; cancer; neurodegenerative diseases; osteoporosis
(This special issue belongs to the Section Molecular Biology)
Feature Papers in the Natural and Bio-Inspired Molecules Section submission deadline 30 Jun 2024 | 3 articles | Viewed by 2594 | Submission Open
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
Advances in Cancer Therapy Resistance
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 2423 | Submission Open
Keywords: cancer therapy resistance; genetic mutations in drug resistance; tumor microenvironment and therapy resistance; epigenetic mediators in drug resistance; cell signaling pathways in therapy failure; combination therapies
(This special issue belongs to the Section Molecular Medicine)
Neuroimmune Interactions in Neuropsychiatric Diseases
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 2118 | Submission Open
Keywords: neurology; psychiatry; immunity; glia
(This special issue belongs to the Section Molecular Biology)
Sterol Biosynthesis and Function in Organisms
edited by Hubert Schaller
submission deadline 30 Jun 2024 | 2 articles | Viewed by 1974 | Submission Open
Keywords: sterol; biosynthesis; function; organisms
(This special issue belongs to the Section Molecular Biology)
Vascular Disease and Thrombosis
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1672 | Submission Open
Keywords: venous thromboembolism; superficial vein thrombosis; deep vein thrombosis; pulmonary embolism; post-thrombotic syndrome; ischemic heart disease; acute myocardial infarction; ischemic stroke; acute limb ischemia; intestinal infarction; biomarkers; hematologic disorders; thrombophilias
(This special issue belongs to the Section Molecular Medicine)
Amyloid-Beta (Aβ) Production/Clearance Balance and Aβ Neurotoxicity in Alzheimer’s Disease: From Mechanisms to Therapy submission deadline 30 Jun 2024 | 1 articles | Viewed by 1608 | Submission Open
Keywords: Alzheimer's disease; amyloid-beta (Aβ ); neurotoxicity of Aβ ; Aβ phagocytosis; Aβ clearance; autophagy-lysosome system; anti-Aβ monoclonal antibodies; catalytides
(This special issue belongs to the Section Cellular Biochemistry)
The Evolution and Function of Repetitive DNA
edited by Raquel Chaves and Sandra Louzada
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1479 | Submission Open
Keywords: repetitive DNA; satellite DNA; transposable elements; non-coding RNA transcripts; evolution of repetitive DNA; genome instability; genome evolution
(This special issue belongs to the Section Molecular Biology)
The Role of Amyloid in Neurological Disorders
edited by and Tamara Berno
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1137 | Submission Open
Keywords: amyloid-beta; neurodegenerative disorders; aducanumab; oligomers; cross-amyloid intraction
(This special issue belongs to the Section Biomacromolecules: Proteins)
The Structure and Function of Proteins, Lipids and Nucleic Acids
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1077 | Submission Open
Keywords: biomacromolecule; biomolecular interactions; biomolecular structure and function; protein folding and stability; biophysical techniques
(This special issue belongs to the Section Molecular Structure and Dynamics)
The Role of Vascular Dysfunction in Neuronal Degeneration and Cognitive Impairment 2.0
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1050 | Submission Open
Keywords: blood cells; plasma components; vascular wall components; neurovascular unit; neuroinflammation; cognitive decline
(This special issue belongs to the Section Molecular Biology)
Biomolecules and Their Impact on Biology and Translational Applications: Celebrating the Pioneering Work of Prof. Ho Jeong Kwon
edited by and Hye Jin Kang
submission deadline 30 Jun 2024 | 1 articles | Viewed by 883 | Submission Open
Keywords: biomolecules; cancer; angiogenesis; autophagy; GPCRs; translational applications; target identification; proximity-labeling; molecular docking; molecular probe; molecular pharmacology
(This special issue belongs to the Section Cellular Biochemistry)
New Insights into Cardiometabolic Diseases submission deadline 30 Jun 2024 | Viewed by 675 | Submission Open
Keywords: metabolic diseases; hypertension; obesity; type-2 diabetes; vascular diseases; acute vascular events
(This special issue belongs to the Section Molecular Medicine)
Neurological Function Study Based on Mass Spectrometry Imaging
edited by Nhu Thi Ngoc Phan
submission deadline 30 Jun 2024 | Viewed by 631 | Submission Open
Keywords: mass spectrometry imaging; secondary ion mass spectrometry (SIMS); matrix-assisted laser desorption/ionization (MALDI); desorption electrospray ionization (DESI); laser ablation– inductively coupled plasma– mass spectrometry imaging (LA-ICP-MSI); multi-isotope imaging mass spectrometry (MIMS); molecular and organelle turnover; brain; neurons; synapses; neuronal stem cells; membrane lipids; synaptic proteins; neural peptides; metabolites; diseases; disorders
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