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Special Issue "Neurodevelopmental Disorders: Linking Genetics and Epigenetics to Disease-Related Pathways"
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 1841
Special Issue Editors
Interests: intellectual disability and developmental epileptic encephalopathies; ARX-KDM5C; disease models; convergent transcriptional pathways
Special Issues, Collections and Topics in MDPI journals
Interests: epigenetics; epigenomics; chromatin diseases; Rett syndrome; MeCP2-mediated molecular mechanisms
Special Issue Information
Neurodevelopmental disorders (NDDs) are a group of genetically heterogeneous diseases in which the development of the central nervous system is disturbed. Identification and functional studies of a large number of NDD genes have been performed over the years, and specific interconnected disease pathways have been discovered. In addition, several NDDs are caused by dysfunctions of epigenetic factors, which often result in large-scale molecular alterations. It is conceivable that targeting a common node in such a disease network could consent to interfering with multiple related NDDs at once.
This Special Issue will focus on distinct and complementary aspects of NDD research: analysis of the molecular mechanisms underlying the intersection of multiple NDD genes involved in specialized brain functions (e.g., chromatin remodeling, neurogenesis, synaptic pruning, neurotransmission, energy metabolism); identification of biomarkers helpful to follow disease onset and age-dependent evolution; and discovery of drugs capable of modulating specific disease networks with encouraging outcomes in cellular and animal models.
Original manuscripts and reviews dealing with any genetic and epigenetic aspect of NDDs and innovative strategies for prevention, diagnosis, and therapeutical intervention are welcome.
Dr. Maria Giuseppina Miano
Dr. Floriana Della Ragione
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- genetics and epigenetics
- convergent disease pathways
- molecular therapies