Special Issue "Marine-Derived Biomolecules II: In Memory of Prof. Paul Scheuer (1915-2003)"

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: closed (15 November 2022) | Viewed by 236

Special Issue Editors

Faculty of Pharmacy, King Abdulaziz University, P.O. Box 80260, Jeddah 21589, Saudi Arabia
Interests: marine natural products; marine invertebrates and associated microbes; cyanobacteria; structural determinations; marine macrolides and toxins; compounds with actin-disruption effects; antitumors and antibiotics; marine chemical ecology
Special Issues, Collections and Topics in MDPI journals
Suez Canal University Hospital, Suez Canal University, Ismailia 41522, Egypt
Interests: marine natural products; marine biodiscovery; invertebrates; cyanobacteria; marine microbes; structure determinations; marine alkaloids; antitumor and antibiotics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The world’s oceans have been shown to provide a rich place with great biodiversity and chemical entities with proven bioactivities related to cancer, inflammation, epilepsy, the immunomodulatory system, microbial and parasitic infections, and many others. Currently, there are eight approved drugs of marine origin and more than 20 other compounds in different clinical phases. Marine invertebrates and micro-organisms represent the major sources of these compounds.

The advantages of studying organisms from the marine environment lie primarily in the breadth of marine biodiversity and the consequent variety of new chemical structures found among marine natural products. Attesting to the tremendous diversity of marine life is the fact that of the 33 animal phyla, 32 are found in the sea, while only 12 occur on land. The larger genetic pool found in the marine environment has resulted in the synthesis of a wide variety of chemicals that can be exploited in a systematic screening program. Many of the primitive phyla that have evolved over the greatest time in the sea appear to have done so using survival mechanisms based on chemical synthesis. The compounds that are responsible for the successful survival of marine organisms possess significant biological activities that often interfere with the essential growth or biosynthetic mechanisms of competing organisms. These are precisely the types of chemicals that might be expected to be active in cancer-related bioassays. Over many millions of years of evolution, marine animals have evolved molecules with high binding affinities toward intracellular targets. The opportunity to apply these “evolutionarily significant molecules” within a mechanism-based drug discovery program is thus a rational approach to targeted drug discovery.

This Special Issue on “Marine-Derived Biomolecules” in Biomolecules will cover all scopes of bioassay-directed fractionation of extracts, purification, and structure mapping of marine-derived molecules as well as their biological activities. Biomolecules from marine macro-organisms and/or microbes, new assays’ development, metabolomics, docking and dereplication of compounds will be targeted in this issue.

As Special Issue Editors, we invite all colleagues who are actively involved in research related to marine biomolecules to share their latest findings and results with other colleagues working in the same field. I hope that this Special Issue will provide deep insights into the importance of marine-derived biomolecules as a future source for drug discovery. I also hope that this issue will inspire junior scientists to look at the huge biodiversity of the marine environment and its future impact as leading sources for drug discovery and development.

Prof. Dr. Diaa Youssef
Prof. Dr. Lamiaa Shaala
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • marine invertebrates and associated microbes
  • seaweed
  • microalgae
  • cyanobacteria
  • blue biotechnology
  • algae
  • structure determinations
  • bioactive compounds
  • dereplication
  • metabolomics
  • docking
  • mode of action of compounds
  • marine nutraceuticals and nutrients

Related Special Issue

Published Papers

There is no accepted submissions to this special issue at this moment.
Back to TopTop