Special Issue "Inflammation and Hemostasis"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 8214
Interests: hemostasis; thrombosis; fibrinolysis; factor XIII; stroke; cardiovascular diseases; clinical studies
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Inflammation and hemostasis are interrelated processes with extensive crosstalk affecting the balance of both systems. Although it was revealed more than 100 years ago that inflammation leads to excessive coagulation activation, most recently, the COVID-19 pandemic has again focused our attention on the importance of the link between these two systems. An excessive immune response may lead to a dysregulation of the hemostasis balance in numerous ways, which may result in thrombotic events, tissue damage, multiorgan failure, and death. Accumulating evidence suggests that the dysregulation of hemostasis, microvascular thrombosis, and hypercoagulability may not only occur during acute inflammatory events but may also play a significant role in the pathogenesis of a number of chronic inflammatory and autoimmune disorders. Although many aspects of the cellular and molecular interactions between hemostasis and inflammation have already been uncovered, today there is renewed interest in clarifying regulatory elements and undiscovered connections of the underlying pathways. Identifying molecular targets and triggers that are key players of the extensive crosstalk between coagulation and inflammation may provide promising therapeutic targets for both inflammatory and thrombotic disorders.
This Special Issue aims to focus on the complex interactions between inflammation and hemostasis with special attention on the unique biological functions and molecular and cellular interactions between these pathways. Submission of original research articles and reviews is encouraged. Research areas may include (but are not limited to) the following:
- Basic research studies exploring novel molecular or cellular interactions in the fields of inflammation and hemostasis (including animal models);
- Clinical studies related to acute or chronic inflammatory states in patients and their effect on the hemostasis system (including studies on COVID-19);
- Studies addressing novel therapeutic targets in inflammatory and/or hemostasis pathways;
- Studies on novel methods, models, or biomarkers of related fields.
We look forward to receiving your contributions.
Dr. Zsuzsa Bagoly
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.