10th Anniversary of Biomolecules—Advances in Biodegradable Biomaterials

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biological and Bio- Materials".

Deadline for manuscript submissions: closed (25 February 2022) | Viewed by 7799

Special Issue Editor

I3B's-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães, Portugal
Interests: biodegradable biomaterials; polymer science; natural origin biomaterials; surface biofunctionalization of biomaterials; innovative therapies for chronic inflammation; nanostructured biomaterials and composites; bone and cartilage tissue engineering; adult stem cells; advanced therapies; regenerative medicine; animal models for testing of biomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This year marks the 10th anniversary of the open access MDPI journal Biomolecules. To celebrate this important occasion, we are delighted and proud to organize a series of Special Issues and events. To date, the journal has received more than 6000 manuscript submissions and published more than 2600 articles, and the journal website attracts more than 26,483 monthly page views. We would like to express our sincerest thanks to our readers, authors, peer reviewers, editors, and all the people contributing in some way to the success of the journal over these 10 years. Without your support, we would never have achieved what we have achieved.

To mark this important milestone, a Special Issue entitled “10th Anniversary of Biomolecules—Recent Advances in Biodegradable Biomaterials” is being launched. This Special Issue will collect original research articles and high-quality review papers in the research fields related to biodegradable biomaterials. We kindly encourage authors actively working in areas contributing to the development of Biodegradable Biomaterials to submit contributions to this important, singular, and very Special Issue.

Keywords of interest include but are not limited to the following:

  • Synthetic biodegradable biomaterials
  • Biologically derived biodegradable biomaterials
  • Ceramic and mineralized biomaterials
  • Protein-based biomaterials
  • Self-assembling biomaterials
  • Surface functionalized biomaterials
  • ECM-derived biomaterials
  • Biodegradable biomaterials in drug delivery applications
  • Clinical use of biodegradable biomaterials

A scientific journal is the collaborative achievement of many scientists from all over the world and we would like to thank all our authors and reviewers who have contributed to this singular and extra-special Special Issue for their support. In recognition of our authors’ continued support, Biomolecules is pleased to announce that the “Biomolecules Best Paper Award for Anniversary Special Issue” will be launched and granted to the 3 papers published in the 10th Anniversary Special Issue and having more citations in the 2 calendar years after publication (2022 and 2023, excluding self-citations). See details at:

https://www.mdpi.com/journal/biomolecules/awards

Dr. Nuno M. Neves
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Synthetic biodegradable biomaterials
  • Biologically derived biodegradable biomaterials
  • Ceramic and mineralized biomaterials
  • Protein-based biomaterials
  • Self-assembling biomaterials
  • Surface functionalized biomaterials
  • ECM-derived biomaterials
  • Biodegradable biomaterials in drug delivery applications
  • Clinical use of biodegradable biomaterials

Published Papers (2 papers)

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Research

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15 pages, 7433 KiB  
Article
Stimulation of Neurite Outgrowth Using Autologous NGF Bound at the Surface of a Fibrous Substrate
Biomolecules 2022, 12(1), 25; https://doi.org/10.3390/biom12010025 - 24 Dec 2021
Cited by 5 | Viewed by 2237
Abstract
Peripheral nerve injury still remains a major clinical challenge, since the available solutions lead to dysfunctional nerve regeneration. Even though autologous nerve grafts are the gold standard, tissue engineered nerve guidance grafts are valid alternatives. Nerve growth factor (NGF) is the most potent [...] Read more.
Peripheral nerve injury still remains a major clinical challenge, since the available solutions lead to dysfunctional nerve regeneration. Even though autologous nerve grafts are the gold standard, tissue engineered nerve guidance grafts are valid alternatives. Nerve growth factor (NGF) is the most potent neurotrophic factor. The development of a nerve guidance graft able to locally potentiate the interaction between injured neurons and autologous NGF would be a safer and more effective alternative to grafts that just release NGF. Herein, a biofunctional electrospun fibrous mesh (eFM) was developed through the selective retrieval of NGF from rat blood plasma. The neurite outgrowth induced by the eFM-NGF systems was assessed by culturing rat pheochromocytoma (PC12) cells for 7 days, without medium supplementation. The biological results showed that this NGF delivery system stimulates neuronal differentiation, enhancing the neurite growth more than the control condition. Full article
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Review

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14 pages, 5143 KiB  
Review
Silk Fibroin-Based Biomaterials for Hemostatic Applications
Biomolecules 2022, 12(5), 660; https://doi.org/10.3390/biom12050660 - 30 Apr 2022
Cited by 18 | Viewed by 4974
Abstract
Hemostasis plays an essential role in all surgical procedures. Uncontrolled hemorrhage is the primary cause of death during surgeries, and effective blood loss control can significantly reduce mortality. For modern surgeons to select the right agent at the right time, they must understand [...] Read more.
Hemostasis plays an essential role in all surgical procedures. Uncontrolled hemorrhage is the primary cause of death during surgeries, and effective blood loss control can significantly reduce mortality. For modern surgeons to select the right agent at the right time, they must understand the mechanisms of action, the effectiveness, and the possible adverse effects of each agent. Over the past decade, various hemostatic agents have grown intensely. These agents vary from absorbable topical hemostats, including collagen, gelatins, microfibrillar, and regenerated oxidized cellulose, to biologically active topical hemostats such as thrombin, biological adhesives, and other combined agents. Commercially available products have since expanded to include topical hemostats, surgical sealants, and adhesives. Silk is a natural protein consisting of fibroin and sericin. Silk fibroin (SF), derived from silkworm Bombyx mori, is a fibrous protein that has been used mostly in fashion textiles and surgical sutures. Additionally, SF has been widely applied as a potential biomaterial in several biomedical and biotechnological fields. Furthermore, SF has been employed as a hemostatic agent in several studies. In this review, we summarize the several morphologic forms of SF and the latest technological advances on the use of SF-based hemostatic agents. Full article
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