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Special Issue "Combined Treatments and Therapies to Cure Spinal Cord Injury"
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 15 November 2023 | Viewed by 7474
Special Issue Editor
Interests: spinal cord injury; cellular transplantation; magnetic stimulation; spinal scar; non-invasive treatment; axonal regrowth; functional recovery; tissue repair
Special Issue Information
Spinal cord injury (SCI) is a rare disease of the central nervous system (CNS), most often originating from trauma following road accidents, falls or violence, causing the loss of motor, sensory and autonomic functions. To date, there is no curative treatment that can be offered to injured patients. The initial trauma induces tissue destruction, the rupture of blood vessels and axons and death of neurons and oligodendrocytes at the site of injury, these events leading to myelin release and inflammation. This reactionary cascade leads to the formation of a spinal scar composed of astrocytes, microglial cells and macrophages, fibroblasts and cystic cavities. This scar has a dual role: beneficial in delimiting the lesioned area, and deleterious in preventing axonal regrowth; thus, leading to a loss of connection between the CNS and the periphery. Many treatments have been tested to allow tissue and functional recovery after SCI. However, the complexity of the injury suggests that a single treatment is not sufficient to induce real benefits in humans. Therefore, it is thought that only the use of combination therapies would be effective in promoting recovery after SCI, although the ideal combination remains to be determined.
We cordially invite you to contribute to the Special Issue entitled “Combined Treatments and Therapies to Cure Spinal Cord Injury”. Our aim is to provide most relevant information concerning innovative treatment modalities and their combinations as potential innovative treatments after SCI. Original investigations and review articles are both welcome.
Dr. Nicolas Guerout
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- spinal cord injury
- tissue repair
- functional recovery
- combined treatments
- innovative therapy
- glial scar
- axonal regrowth