Novel Therapeutic Nutrient Molecules 2.0

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Drug Discovery, Development and Delivery".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 5963

Special Issue Editors

Department of Nutrition and Health Sciences, College of Education and Human Sciences, University of Nebraska at Lincoln, Lincoln, NE 68583, USA
Interests: maternal obesity; placental lipotoxicity; metabolic dysfunction-associated steatotic liver disease; apoptosis; liver cirrhosis; proline metabolism
Special Issues, Collections and Topics in MDPI journals
College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE 68198, USA
Interests: maternal–fetal nutrient interaction; the effects of omega-3 fatty acids against adverse pregnancy outcomes such as preterm
Special Issues, Collections and Topics in MDPI journals
Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA
Interests: metabolic diseases;inflammation;dietary molecules
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue entitled “Novel Therapeutic Nutrient Molecules” will focus on the protective role of bioactive nutrient molecules as a therapeutic approach and against disease pathogenesis.

The identification of novel nutrient molecules for therapeutics or to prevent disease pathogenesis has been an attractive approach due to the ease of their translation to the general population. Recent advances in bioactive nutrient molecules protecting against human health outcomes has always been a growing field, with constant acquisition of new knowledge.

Our Special Issue will consider original articles, commentary, and review articles that focus on the following potential topics (but are not limited to these):

  • Investigations related to the nutrients of foods and their effects in improving human health.
  • Investigations related to novel nutrient compounds and their impact on the human gut microbiome and gut health.
  • Investigations related to the gut bioactive metabolites of nutrient molecules and their impact on human health.
  • The novel protective roles of vitamins and their metabolites against adverse health outcomes.

Keywords

  • bioactive nutrient molecules
  • novel compounds in extracellular vesicles
  • gut microbial metabolites
  • novel gut metabolites of food

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Published Papers (1 paper)

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Review

19 pages, 355 KiB  
Review
The Relationships between Gut Microbiota and Diabetes Mellitus, and Treatments for Diabetes Mellitus
by Cristian-Ioan Craciun, Maria-Adriana Neag, Adrian Catinean, Andrei-Otto Mitre, Adriana Rusu, Cornelia Bala, Gabriela Roman, Anca-Dana Buzoianu, Dana-Maria Muntean and Anca-Elena Craciun
Biomedicines 2022, 10(2), 308; https://doi.org/10.3390/biomedicines10020308 - 28 Jan 2022
Cited by 17 | Viewed by 5144
Abstract
Diabetes mellitus is considered to be a global epidemic. The combination of genetic susceptibility and an unhealthy lifestyle is considered to be the main trigger of this metabolic disorder. Recently, there has been increased interest in the roles of gut microbiota as a [...] Read more.
Diabetes mellitus is considered to be a global epidemic. The combination of genetic susceptibility and an unhealthy lifestyle is considered to be the main trigger of this metabolic disorder. Recently, there has been increased interest in the roles of gut microbiota as a new potential contributor to this epidemic. Research, in recent years, has contributed to an in-depth characterization of the human microbiome and its associations with various diseases, including metabolic diseases and diabetes mellitus. It is known that diet can change the composition of gut microbiota, but it is unclear how this, in turn, may influence metabolism. The main objective of this review is to evaluate the pathogenetic association between microbiota and diabetes and to explore any new therapeutic agents, including nutraceuticals that may modulate the microbiota. We also look at several mechanisms involved in this process. There is a clear, bidirectional relationship between microbiota and diabetes. Current treatments for diabetes influence microbiota in various ways, some beneficial, but others with still unclear effects. Microbiota-aimed treatments have seen no real-world significant effects on the progression of diabetes and its complications, with more studies needed in order to find a really beneficial agent. Full article
(This article belongs to the Special Issue Novel Therapeutic Nutrient Molecules 2.0)
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