Insights into Psychiatric Disorders from a Neuroimaging Perspective

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".

Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 2109

Special Issue Editor

1. MIPA, Department of Art and Science, University of Nîmes, Nîmes, France
2. Departments of Radiology and Psychiatry, University Hospital Center of Nimes, Nîmes, France
Interests: brain connectivity; neuroimaging; suicide; computational neurosciences; multivariate analysis; neuropsychiatric disorders

Special Issue Information

Dear Colleagues,

Advances in neuroimaging technology have opened up tremendous possibilities for assessing the living brain. However, mapping features of the pathological mind is an even more complex task. While mental illnesses are defined clinically, posing evidence about their pathophysiological mechanisms usually requires a transdisciplinary team alongside cutting-edge multimodal imaging approaches. Indeed, current trends in neuropsychiatry are essentially multifactorial issues in which neuroimaging-informed markers play a key, albeit challenging, role in highlighting subtle neurobiological abnormalities.

This Special Issue of Biomedicines aims to provide a suitable forum to tackle such challenges. We are eager to foster clinical and experimental neuroscientists who wish to share their discoveries about (1) early or predictable diagnosis; (2) the efficacy of an innovative therapy or a novel therapeutic regimen; and (3) the accurate prognosis of neuropsychiatric disorders that are supported by neuroimaging substrates. We welcome original articles, clinical or pre-clinical trial studies, and comprehensive reviews related (but not limited) to:

  • Psychiatric neuroimaging;
  • Advances of molecular imaging;
  • Neuroimaging-informed phenotypes;
  • Image-based neuropsychiatric diagnosis and prognosis;
  • Drug delivery and pharmacological MRI;
  • Translational psychiatry;
  • Multimodal neuroimaging;
  • Neuromodulation and neurostimulation;
  • Personalized and complementary medicine;
  • Computational psychiatry;
  • Gut-brain interactions.

Dr. Fabrício Pereira
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • suicide
  • affective disorders
  • personality disorders
  • behavioral disorders
  • translational psychiatry
  • psychiatric neuroimaging
  • brain connectivity
  • multivariate analysis
  • animal model
  • optogenetics

Published Papers (1 paper)

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Research

12 pages, 922 KiB  
Article
The Executive Functioning Paradox in Substance Use Disorders
by Louise Jakubiec, Valentine Chirokoff, Majd Abdallah, Ernesto Sanz-Arigita, Maud Dupuy, Joel Swendsen, Sylvie Berthoz, Fabien Gierski, Sarah Guionnet, David Misdrahi, Fuschia Serre, Marc Auriacombe and Melina Fatseas
Biomedicines 2022, 10(11), 2728; https://doi.org/10.3390/biomedicines10112728 - 28 Oct 2022
Cited by 3 | Viewed by 1666
Abstract
Deficits in neurocognitive functioning are trait-like vulnerabilities that have been widely studied in persons with substance use disorders (SUD), but their role in the craving–use association and relapse vulnerability remains poorly understood. The main objectives of this study were to examine whether executive [...] Read more.
Deficits in neurocognitive functioning are trait-like vulnerabilities that have been widely studied in persons with substance use disorders (SUD), but their role in the craving–use association and relapse vulnerability remains poorly understood. The main objectives of this study were to examine whether executive capacities moderate the magnitude of the craving–substance use relationship, and if this influence is correlated with the functional connectivity of cerebral networks, combining rsfMRI examinations and ecological momentary assessment (EMA). Eighty-six patients beginning outpatient treatment for alcohol, tobacco or cannabis addiction and 40 healthy controls completed neuropsychological tests followed by EMA to collect real-time data on craving. Fifty-four patients and 30 healthy controls also completed a resting-state fMRI before the EMA. Among the patients with SUD, better verbal fluency and resistance to interference capacities were associated with a greater propensity to use substances when the individual was experiencing craving. Preliminary rsfMRI results identified specific networks that interacted with executive performance capacities to influence the magnitude of the craving–use association. Individuals with better executive functioning may be more prone to relapse after craving episodes. Specifically, better resistance to interference and cognitive flexibility skills may reduce attention to distracting stimuli, leading to a greater awareness of craving and susceptibility to use substances. Full article
(This article belongs to the Special Issue Insights into Psychiatric Disorders from a Neuroimaging Perspective)
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