Autonomic Dysfunction in Neurological Disorders: Novel Mechanisms and Targets

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".

Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 208

Special Issue Editors

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Guest Editor
Department of Medicine, Center for Precision Medicine, University of Missouri, Columbia, MO 65203, USA
Interests: autonomic nervous system; synaptic plasticity in neurological disorders; Ion channel

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Guest Editor
UCF College of Medicine, Orlando, FL, USA
Interests: cardiovascular autonomic nerve innervation; digestive system autonomic innervation; gut-brain interaction

Special Issue Information

Dear Colleagues,

The dysfunction of the autonomic nervous system is associated with many neurological diseases as a consequence or causality of primary diseases. Studies have been carried out to determine the mechanisms of dysautonomia in neurological disorders such as Alzheimer’s disease, Parkinson’s disease, depression, and neurogenic hypertension. In addition, dysautonomia also importantly contributes to metabolic diseases, such as diabetes, obesity, and metabolic syndrome, because it may lead to insulin resistance, altered lipid metabolism, and hypertension in metabolic syndrome. In a certain sensorium, autonomic dysfunction is associated with multiple diseases (e.g., diabetes mellitus and depression), suggesting that autonomic dysfunction is possibly a common mechanism that governs their pathological process. However, the role of autonomic dysfunction in creating or maintaining the pathology of neurological diseases is not still completely understood. Recovering altered autonomic function provides a potential therapy that can be used to treat certain neurological diseases. This Special Issue invites investigators to contribute original research articles and review articles that will help us understand the novel mechanisms of autonomic dysfunction in neurological diseases. Potential topics include, but are not limited to, the following: autonomic dysfunction in neurological disorders (such as Alzheimer's disease, Parkinson's disease, and depression); dysautonomia in insulin resistance in metabolic diseases; and dysautonomia in response to external environmental changes (such as stress, traumatic brain injury, or hormonal imbalances).

Dr. De-Pei Li
Prof. Dr. Zixi Cheng
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • sympathetic nervous system
  • parasympathetic nervous system
  • novel mechanisms
  • novel molecular
  • genetic predisposition

Published Papers

There is no accepted submissions to this special issue at this moment.
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