Emerging Topics in Male Reproductive Health
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 506
Special Issue Editors
Interests: metabolism; mitochondria; omics; andrology; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Interests: human male fertility; cell culture; genetics; reproductive medicine; reproductive biology
Interests: male fertility; antioxidants; sperm quality; oxidative stress; cell metabolism and bioenergetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The worldwide prevalence of infertility is increasing, and in 50% of infertile couples the cause of infertility is attributed to the male partner. There are numerous causes that alter the quality of sperm parameters and thus affect male fertility, including the presence of varicoceles, hypogonadism, genetic disorders, metabolic diseases, eating and drinking habits, and many other disorders.
However, there are also many cases of infertility where the cause remains unknown. Idiopathic infertility is diagnosed when the male has normal semen parameters and his female partner has regular ovulatory parameters. These cases represent 15–30% of all infertile couples. The present methods for semen examination provide limited answers, and there are still many questions that require further research. Over the past few years, new evidence has emerged showing that men with sperm parameters that are apparently within normal ranges may have underlying molecular abnormalities that decrease fertility. It is necessary to deepen the knowledge about metabolic and signaling pathways involved in sperm function; mechanisms involved in its maturation and capacitation; the adaptation of sperm to different environments during transit in the male and female reproductive tracts; damage to sperm DNA and its causes; among many other molecular mechanisms that lead to fertilization failure.
This Special Issue will primarily focus on aspects related to the molecular biology and laboratory medicine of male reproductive health, and thus papers containing only clinical outcomes and lifestyle are not acceptable.
Dr. Marco G. Alves
Dr. Raquel L. Bernardino
Prof. Dr. Pedro F. Oliveira
Guest Editors
Manuscript Submission Information
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Keywords
- male reproduction
- sperm parameters
- genetic disorders
- metabolic diseases
- infertility
