Special Issue "The Role of Telomere and Telomerase in Human Disease"

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 215

Special Issue Editor

Rabin Medical Center Israel, Petah Tiqwa, Israel
Interests: exosomes; microenvironment; telomeres; telomerase; hematological cancers
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Telomeres and telomerase have received an ever-increasing interest from the scientific community. The telomere/telomerase complex is the key element that determines unlimited replicative potential. Telomere shortening occurs at each round of cell division, accompanied by DNA synthesis, restricts cell proliferation and induces cell senescence and apoptosis in checkpoint-proficient normal somatic cells. Telomerase is a reverse transcriptase that maintains the length of telomere, endowing cells with the ability to proliferate indefinitely. Thus, the telomere/telomerase interaction plays a key role in the initiation and progression of diseases such as cancer and aging, making this complex an attractive therapeutic target.

In this Special Issue, entitled “The Role of Telomeres and Telomerase in Human Disease”, we welcome original studies and review articles presenting novel findings at the basic and translational levels of research in this field. Specifically, we are interested in the following issues: 1. the roles of shelterin and other proteins in telomere lengths regulation; 2. telomerase as an anticancer drug target; 3. extracurricular activities of telomerase; and 4. the role of telomerase in various diseases.

Dr. Orit Uziel
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • telomere
  • telomerase
  • cancer
  • aging

Published Papers

This special issue is now open for submission.
Back to TopTop