Pathogenesis and Treatment Progress of Chronic Kidney Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 24631
Special Issue Editor
Interests: glomerulonephritis; podocyte biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic kidney disease (CKD) care has been recognized by the WHO as one of global burdens, and the related health threat is becoming more serious in most countries. Understanding the detailed pathogenesis is of prime importance to ameliorate disease care and improve outcome. Aging and metabolic derangement are undoubtedly universal causes, even though the pathogenic factors may vary between areas and countries. Against the backdrop of hyperendemic obesity and epidemic diabetes, diabetic kidney disease has taken over a large part of clinical care in nephrology practice. Nevertheless, glomerulonephritis is still prevalent, and the principal role of basic researches on cellular pathogenic mechanism still holds. In the past, it is fair to state that there is no specific pharmacological treatment for CKD, with only a renin-angiotensin system blockade and others which are rare and barely qualified. Optimistically, several lines of recently developed agents have cast new light on the effective treatment of CKD. Of them, inhibitors of sodium-dependent glucose cotransporters receive the most worldwide attention. Clinical studies with other lines of medications are ongoing and may hopefully reshape the specific treatment in the future. Eventually, we can advance the care of chronic kidney disease patients through the continuous efforts of both basic and clinical researches.
Dr. Jer-Ming Chang
Guest Editor
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Keywords
- kidney disease
- kidney health
- chronic kidney disease
- glomerulonephritis
- diabetic kidney disease
- SGLT2i