Special Issue "Fatty Liver Disease: From Mechanisms to Therapeutic Approaches"

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".

Deadline for manuscript submissions: 31 March 2024 | Viewed by 26

Special Issue Editor

Dr. Mirela Baus Lončar
E-Mail Website
Guest Editor
Institute Ruder Boskovic, Zagreb, Croatia
Interests: trefoil family petides (Tffs); gut-liver-brain axis, animal model of Tff3 deficiency; metabolism

Special Issue Information

Dear Colleagues,

The liver, as the largest organ, participates in food digestion, energy storage and the removal of toxic substances removal from the body, thus having a major impact on the general health of patients. Excessive buildup of fat in the liver is known as fatty liver, which is becoming increasingly common around the world. Mechanistic accumulation of fat can be related to alcohol toxicity, but the majority of cases nowadays are non-alcohol-related, so this form of fatty liver disease has been renamed to Metabolic dysfunction-associated fatty liver disease (MAFLD). This suggests that a plethora of possible mechanisms are involved in the buildup of fat in the liver, with the possible impact of sex hormones on metabolism needing further study. Excessive fat accumulation can go unnoticed until serious liver dysfunction occurs, disrupting organism homeostasis and possibly resulting in extrahepatic organ pathologies. Fatty liver disease coexists with other diseases like diabetes, cardiovascular diseases, and neurodegenerative diseases, and their connection can no longer be overlooked.

Manuscripts that are being accepted for this Special Issue are those that address the mechanisms of fat accumulation, correlation with other diseases, and the possible effects of sex differences. In addition, manuscripts addressing clinical data, possible early detection, and therapies for fatty liver are also welcome.

Dr. Mirela Baus Lončar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • fatty liver
  • metabolism
  • animal models of disease
  • gut–liver–brain axis
  • therapy

Published Papers

This special issue is now open for submission.
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